| Full name: kinesin family member 21A | Alias Symbol: FLJ20052 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 55605 | HGNC ID: HGNC:19349 | Ensembl Gene: ENSG00000139116 | OMIM ID: 608283 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF21A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF21A | 55605 | 226003_at | -0.1679 | 0.8797 | |
| GSE26886 | KIF21A | 55605 | 226003_at | -1.9342 | 0.0000 | |
| GSE45670 | KIF21A | 55605 | 226003_at | -0.6531 | 0.0128 | |
| GSE63941 | KIF21A | 55605 | 226003_at | 2.5326 | 0.0017 | |
| GSE77861 | KIF21A | 55605 | 226003_at | -0.8005 | 0.1171 | |
| GSE97050 | KIF21A | 55605 | A_23_P113462 | -0.3656 | 0.3989 | |
| SRP007169 | KIF21A | 55605 | RNAseq | -0.0299 | 0.9386 | |
| SRP008496 | KIF21A | 55605 | RNAseq | -0.3298 | 0.2854 | |
| SRP064894 | KIF21A | 55605 | RNAseq | -2.0986 | 0.0000 | |
| SRP133303 | KIF21A | 55605 | RNAseq | -0.6921 | 0.0564 | |
| SRP159526 | KIF21A | 55605 | RNAseq | -0.1958 | 0.6516 | |
| SRP193095 | KIF21A | 55605 | RNAseq | -1.1809 | 0.0000 | |
| SRP219564 | KIF21A | 55605 | RNAseq | -1.2252 | 0.0679 | |
| TCGA | KIF21A | 55605 | RNAseq | -0.1586 | 0.0311 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by KIF21A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KIF21A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF21A | 55605 | 6 | 1 | 23 | |
| GSE20123 | KIF21A | 55605 | 6 | 1 | 23 | |
| GSE43470 | KIF21A | 55605 | 5 | 3 | 35 | |
| GSE46452 | KIF21A | 55605 | 8 | 1 | 50 | |
| GSE47630 | KIF21A | 55605 | 11 | 2 | 27 | |
| GSE54993 | KIF21A | 55605 | 1 | 8 | 61 | |
| GSE54994 | KIF21A | 55605 | 7 | 1 | 45 | |
| GSE60625 | KIF21A | 55605 | 0 | 0 | 11 | |
| GSE74703 | KIF21A | 55605 | 4 | 2 | 30 | |
| GSE74704 | KIF21A | 55605 | 3 | 1 | 16 | |
| TCGA | KIF21A | 55605 | 17 | 14 | 65 |
Total number of gains: 68; Total number of losses: 34; Total Number of normals: 386.
Somatic mutations of KIF21A:
Generating mutation plots.
Highly correlated genes for KIF21A:
Showing top 20/851 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF21A | SH2D3A | 0.784834 | 3 | 0 | 3 |
| KIF21A | FRMD4B | 0.780129 | 6 | 0 | 6 |
| KIF21A | SH3BGRL2 | 0.772722 | 4 | 0 | 4 |
| KIF21A | DAPP1 | 0.772143 | 4 | 0 | 4 |
| KIF21A | PAQR8 | 0.768031 | 4 | 0 | 4 |
| KIF21A | DGKA | 0.759857 | 5 | 0 | 5 |
| KIF21A | ZNF823 | 0.756501 | 5 | 0 | 5 |
| KIF21A | ZNF431 | 0.753836 | 4 | 0 | 4 |
| KIF21A | YOD1 | 0.753344 | 5 | 0 | 5 |
| KIF21A | FAM214A | 0.751936 | 3 | 0 | 3 |
| KIF21A | SLC16A6 | 0.747926 | 4 | 0 | 4 |
| KIF21A | CRISP3 | 0.745707 | 4 | 0 | 4 |
| KIF21A | ZNF92 | 0.743255 | 3 | 0 | 3 |
| KIF21A | IL18 | 0.742834 | 4 | 0 | 4 |
| KIF21A | STRN | 0.74252 | 5 | 0 | 4 |
| KIF21A | TMEM41B | 0.741184 | 3 | 0 | 3 |
| KIF21A | HSBP1L1 | 0.738724 | 4 | 0 | 4 |
| KIF21A | STYK1 | 0.738689 | 3 | 0 | 3 |
| KIF21A | HERC6 | 0.735781 | 3 | 0 | 3 |
| KIF21A | RAB11A | 0.735323 | 5 | 0 | 5 |
For details and further investigation, click here
