| Full name: coenzyme Q10A | Alias Symbol: FLJ32452 | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 93058 | HGNC ID: HGNC:26515 | Ensembl Gene: ENSG00000135469 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of COQ10A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ10A | 93058 | 225747_at | -0.2644 | 0.6374 | |
| GSE26886 | COQ10A | 93058 | 225747_at | -0.0794 | 0.7608 | |
| GSE45670 | COQ10A | 93058 | 225747_at | -0.1553 | 0.3942 | |
| GSE53622 | COQ10A | 93058 | 113398 | 0.0032 | 0.9741 | |
| GSE53624 | COQ10A | 93058 | 113398 | 0.2779 | 0.0004 | |
| GSE63941 | COQ10A | 93058 | 225747_at | -0.1725 | 0.7866 | |
| GSE77861 | COQ10A | 93058 | 225747_at | -0.0330 | 0.8608 | |
| GSE97050 | COQ10A | 93058 | A_23_P354798 | -0.1845 | 0.3603 | |
| SRP007169 | COQ10A | 93058 | RNAseq | 0.1958 | 0.7485 | |
| SRP008496 | COQ10A | 93058 | RNAseq | 0.3098 | 0.4732 | |
| SRP064894 | COQ10A | 93058 | RNAseq | 0.4277 | 0.0246 | |
| SRP133303 | COQ10A | 93058 | RNAseq | -0.1469 | 0.5181 | |
| SRP159526 | COQ10A | 93058 | RNAseq | 0.3975 | 0.1818 | |
| SRP193095 | COQ10A | 93058 | RNAseq | 0.0136 | 0.8972 | |
| SRP219564 | COQ10A | 93058 | RNAseq | -0.0468 | 0.9263 | |
| TCGA | COQ10A | 93058 | RNAseq | -0.1765 | 0.0738 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COQ10A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ10A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ10A | 93058 | 7 | 2 | 21 | |
| GSE20123 | COQ10A | 93058 | 7 | 1 | 22 | |
| GSE43470 | COQ10A | 93058 | 4 | 0 | 39 | |
| GSE46452 | COQ10A | 93058 | 8 | 1 | 50 | |
| GSE47630 | COQ10A | 93058 | 10 | 2 | 28 | |
| GSE54993 | COQ10A | 93058 | 0 | 5 | 65 | |
| GSE54994 | COQ10A | 93058 | 4 | 1 | 48 | |
| GSE60625 | COQ10A | 93058 | 0 | 0 | 11 | |
| GSE74703 | COQ10A | 93058 | 4 | 0 | 32 | |
| GSE74704 | COQ10A | 93058 | 4 | 1 | 15 | |
| TCGA | COQ10A | 93058 | 14 | 10 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of COQ10A:
Generating mutation plots.
Highly correlated genes for COQ10A:
Showing top 20/174 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ10A | DOCK1 | 0.740133 | 3 | 0 | 3 |
| COQ10A | L3MBTL3 | 0.702974 | 3 | 0 | 3 |
| COQ10A | KCNT2 | 0.686186 | 3 | 0 | 3 |
| COQ10A | WDR49 | 0.680654 | 3 | 0 | 3 |
| COQ10A | SENP8 | 0.675116 | 3 | 0 | 3 |
| COQ10A | MYEF2 | 0.674328 | 4 | 0 | 3 |
| COQ10A | TBRG4 | 0.669476 | 3 | 0 | 3 |
| COQ10A | ACSS1 | 0.662498 | 4 | 0 | 3 |
| COQ10A | TCTEX1D2 | 0.657638 | 3 | 0 | 3 |
| COQ10A | PARM1 | 0.650366 | 3 | 0 | 3 |
| COQ10A | MECP2 | 0.646642 | 4 | 0 | 3 |
| COQ10A | SMURF2 | 0.643617 | 3 | 0 | 3 |
| COQ10A | ZMAT1 | 0.634523 | 5 | 0 | 4 |
| COQ10A | DDX50 | 0.633322 | 4 | 0 | 3 |
| COQ10A | ZSCAN16 | 0.632362 | 3 | 0 | 3 |
| COQ10A | NR3C2 | 0.630314 | 3 | 0 | 3 |
| COQ10A | SNAPIN | 0.630268 | 3 | 0 | 3 |
| COQ10A | F8 | 0.627133 | 5 | 0 | 4 |
| COQ10A | MSI2 | 0.626898 | 4 | 0 | 3 |
| COQ10A | RECK | 0.624284 | 4 | 0 | 3 |
For details and further investigation, click here
