| Full name: WD repeat domain 49 | Alias Symbol: FLJ33620 | ||
| Type: protein-coding gene | Cytoband: 3q26.1 | ||
| Entrez ID: 151790 | HGNC ID: HGNC:26587 | Ensembl Gene: ENSG00000174776 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR49 | 151790 | 1564238_a_at | -0.1362 | 0.6702 | |
| GSE26886 | WDR49 | 151790 | 1564238_a_at | -0.2463 | 0.0258 | |
| GSE45670 | WDR49 | 151790 | 1564238_a_at | 0.0198 | 0.8848 | |
| GSE53622 | WDR49 | 151790 | 60342 | -1.9172 | 0.0000 | |
| GSE53624 | WDR49 | 151790 | 42795 | -1.8287 | 0.0000 | |
| GSE63941 | WDR49 | 151790 | 1564238_a_at | -0.0223 | 0.9240 | |
| GSE77861 | WDR49 | 151790 | 1564238_a_at | -0.1131 | 0.2946 | |
| GSE97050 | WDR49 | 151790 | A_33_P3256844 | -0.6707 | 0.2434 | |
| SRP133303 | WDR49 | 151790 | RNAseq | -0.8205 | 0.1808 | |
| SRP159526 | WDR49 | 151790 | RNAseq | -1.6141 | 0.0212 | |
| TCGA | WDR49 | 151790 | RNAseq | 0.4948 | 0.5647 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by WDR49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR49 | 151790 | 22 | 0 | 8 | |
| GSE20123 | WDR49 | 151790 | 22 | 0 | 8 | |
| GSE43470 | WDR49 | 151790 | 23 | 0 | 20 | |
| GSE46452 | WDR49 | 151790 | 19 | 1 | 39 | |
| GSE47630 | WDR49 | 151790 | 27 | 2 | 11 | |
| GSE54993 | WDR49 | 151790 | 1 | 13 | 56 | |
| GSE54994 | WDR49 | 151790 | 41 | 0 | 12 | |
| GSE60625 | WDR49 | 151790 | 0 | 6 | 5 | |
| GSE74703 | WDR49 | 151790 | 19 | 0 | 17 | |
| GSE74704 | WDR49 | 151790 | 14 | 0 | 6 | |
| TCGA | WDR49 | 151790 | 79 | 0 | 17 |
Total number of gains: 267; Total number of losses: 22; Total Number of normals: 199.
Somatic mutations of WDR49:
Generating mutation plots.
Highly correlated genes for WDR49:
Showing top 20/350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR49 | CASQ2 | 0.711119 | 4 | 0 | 4 |
| WDR49 | MYOM2 | 0.708775 | 3 | 0 | 3 |
| WDR49 | CBX7 | 0.708334 | 4 | 0 | 4 |
| WDR49 | TSHZ1 | 0.702909 | 4 | 0 | 4 |
| WDR49 | PPP1R9A | 0.70276 | 4 | 0 | 4 |
| WDR49 | PYGM | 0.702288 | 4 | 0 | 4 |
| WDR49 | PGM5 | 0.700422 | 4 | 0 | 4 |
| WDR49 | NR3C2 | 0.699491 | 4 | 0 | 4 |
| WDR49 | NTN1 | 0.695702 | 4 | 0 | 3 |
| WDR49 | TGFBR3 | 0.693446 | 4 | 0 | 4 |
| WDR49 | SORBS2 | 0.693053 | 5 | 0 | 5 |
| WDR49 | KAT6B | 0.683021 | 4 | 0 | 4 |
| WDR49 | PPP1R12B | 0.682745 | 4 | 0 | 4 |
| WDR49 | PRKAR2B | 0.681796 | 4 | 0 | 4 |
| WDR49 | COQ10A | 0.680654 | 3 | 0 | 3 |
| WDR49 | ANGPTL1 | 0.679902 | 4 | 0 | 4 |
| WDR49 | FAM13C | 0.679312 | 3 | 0 | 3 |
| WDR49 | PRKAA2 | 0.679124 | 4 | 0 | 4 |
| WDR49 | PDK4 | 0.678564 | 3 | 0 | 3 |
| WDR49 | ABCA8 | 0.677393 | 4 | 0 | 4 |
For details and further investigation, click here
