| Full name: ring finger and CCCH-type domains 2 | Alias Symbol: FLJ20301|FLJ20713|RNF164 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 54542 | HGNC ID: HGNC:21461 | Ensembl Gene: ENSG00000056586 | OMIM ID: 615231 |
| Drug and gene relationship at DGIdb | |||
Expression of RC3H2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RC3H2 | 54542 | 225813_at | 0.1556 | 0.4826 | |
| GSE20347 | RC3H2 | 54542 | 220202_s_at | -0.0296 | 0.8982 | |
| GSE23400 | RC3H2 | 54542 | 220202_s_at | 0.4333 | 0.0000 | |
| GSE26886 | RC3H2 | 54542 | 220201_at | -0.3203 | 0.2020 | |
| GSE29001 | RC3H2 | 54542 | 220201_at | -0.4045 | 0.2516 | |
| GSE38129 | RC3H2 | 54542 | 220202_s_at | 0.1191 | 0.5042 | |
| GSE45670 | RC3H2 | 54542 | 225813_at | 0.1373 | 0.2812 | |
| GSE53622 | RC3H2 | 54542 | 36508 | 0.4143 | 0.0000 | |
| GSE53624 | RC3H2 | 54542 | 53655 | 0.3620 | 0.0000 | |
| GSE63941 | RC3H2 | 54542 | 231716_at | 1.3383 | 0.0013 | |
| GSE77861 | RC3H2 | 54542 | 231716_at | 0.6045 | 0.0625 | |
| GSE97050 | RC3H2 | 54542 | A_33_P3345504 | 0.3485 | 0.1517 | |
| SRP007169 | RC3H2 | 54542 | RNAseq | 0.9130 | 0.0127 | |
| SRP008496 | RC3H2 | 54542 | RNAseq | 1.0862 | 0.0000 | |
| SRP064894 | RC3H2 | 54542 | RNAseq | 0.2035 | 0.1684 | |
| SRP133303 | RC3H2 | 54542 | RNAseq | 0.4154 | 0.0062 | |
| SRP159526 | RC3H2 | 54542 | RNAseq | -0.0332 | 0.8916 | |
| SRP193095 | RC3H2 | 54542 | RNAseq | 0.1170 | 0.2185 | |
| SRP219564 | RC3H2 | 54542 | RNAseq | -0.2092 | 0.4687 | |
| TCGA | RC3H2 | 54542 | RNAseq | 0.0318 | 0.6374 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RC3H2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RC3H2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RC3H2 | 54542 | 3 | 9 | 18 | |
| GSE20123 | RC3H2 | 54542 | 3 | 9 | 18 | |
| GSE43470 | RC3H2 | 54542 | 5 | 3 | 35 | |
| GSE46452 | RC3H2 | 54542 | 6 | 13 | 40 | |
| GSE47630 | RC3H2 | 54542 | 3 | 16 | 21 | |
| GSE54993 | RC3H2 | 54542 | 3 | 3 | 64 | |
| GSE54994 | RC3H2 | 54542 | 9 | 10 | 34 | |
| GSE60625 | RC3H2 | 54542 | 0 | 0 | 11 | |
| GSE74703 | RC3H2 | 54542 | 5 | 3 | 28 | |
| GSE74704 | RC3H2 | 54542 | 2 | 6 | 12 | |
| TCGA | RC3H2 | 54542 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 96; Total Number of normals: 326.
Somatic mutations of RC3H2:
Generating mutation plots.
Highly correlated genes for RC3H2:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RC3H2 | COQ10B | 0.754333 | 3 | 0 | 3 |
| RC3H2 | FAM86C1 | 0.741016 | 3 | 0 | 3 |
| RC3H2 | GNG10 | 0.736953 | 3 | 0 | 3 |
| RC3H2 | SET | 0.727383 | 5 | 0 | 5 |
| RC3H2 | TRAPPC1 | 0.724813 | 3 | 0 | 3 |
| RC3H2 | TPMT | 0.720671 | 3 | 0 | 3 |
| RC3H2 | TMEM138 | 0.717353 | 4 | 0 | 4 |
| RC3H2 | EIF3C | 0.713588 | 3 | 0 | 3 |
| RC3H2 | RBMX | 0.702652 | 3 | 0 | 3 |
| RC3H2 | RAB34 | 0.69042 | 3 | 0 | 3 |
| RC3H2 | POP5 | 0.689736 | 3 | 0 | 3 |
| RC3H2 | SCRN3 | 0.68613 | 3 | 0 | 3 |
| RC3H2 | DLGAP4 | 0.682965 | 4 | 0 | 4 |
| RC3H2 | UBE2M | 0.675554 | 3 | 0 | 3 |
| RC3H2 | ACER3 | 0.674707 | 3 | 0 | 3 |
| RC3H2 | PPP1R9B | 0.673536 | 4 | 0 | 3 |
| RC3H2 | CMTM4 | 0.665509 | 5 | 0 | 4 |
| RC3H2 | RUNX3 | 0.664844 | 4 | 0 | 3 |
| RC3H2 | SLC25A43 | 0.66351 | 3 | 0 | 3 |
| RC3H2 | PSMB7 | 0.655747 | 11 | 0 | 10 |
For details and further investigation, click here
