| Full name: SRA stem-loop interacting RNA binding protein | Alias Symbol: DC50 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 81892 | HGNC ID: HGNC:20495 | Ensembl Gene: ENSG00000119705 | OMIM ID: 610211 |
Screen Evidence:
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Expression of SLIRP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLIRP | 81892 | 221434_s_at | 0.1736 | 0.6321 | |
| GSE20347 | SLIRP | 81892 | 221434_s_at | 0.2418 | 0.1867 | |
| GSE23400 | SLIRP | 81892 | 221434_s_at | 0.5509 | 0.0000 | |
| GSE26886 | SLIRP | 81892 | 221434_s_at | 0.6533 | 0.0024 | |
| GSE29001 | SLIRP | 81892 | 221434_s_at | 0.3106 | 0.1800 | |
| GSE38129 | SLIRP | 81892 | 221434_s_at | 0.2888 | 0.0389 | |
| GSE45670 | SLIRP | 81892 | 221434_s_at | 0.3993 | 0.0069 | |
| GSE53622 | SLIRP | 81892 | 3660 | 0.3808 | 0.0000 | |
| GSE53624 | SLIRP | 81892 | 3660 | 0.7313 | 0.0000 | |
| GSE63941 | SLIRP | 81892 | 221434_s_at | 0.2607 | 0.5348 | |
| GSE77861 | SLIRP | 81892 | 221434_s_at | -0.0075 | 0.9883 | |
| GSE97050 | SLIRP | 81892 | A_23_P128991 | 0.3404 | 0.3182 | |
| SRP007169 | SLIRP | 81892 | RNAseq | 0.1712 | 0.6376 | |
| SRP008496 | SLIRP | 81892 | RNAseq | 0.1362 | 0.6558 | |
| SRP064894 | SLIRP | 81892 | RNAseq | 0.3665 | 0.2627 | |
| SRP133303 | SLIRP | 81892 | RNAseq | 0.5405 | 0.0026 | |
| SRP159526 | SLIRP | 81892 | RNAseq | 0.2350 | 0.5632 | |
| SRP193095 | SLIRP | 81892 | RNAseq | -0.2900 | 0.1531 | |
| SRP219564 | SLIRP | 81892 | RNAseq | 0.1665 | 0.6932 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLIRP expression:
Note: Click image to view full size file.
Copy number change of SLIRP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLIRP | 81892 | 7 | 3 | 20 | |
| GSE20123 | SLIRP | 81892 | 7 | 3 | 20 | |
| GSE43470 | SLIRP | 81892 | 8 | 3 | 32 | |
| GSE46452 | SLIRP | 81892 | 16 | 3 | 40 | |
| GSE47630 | SLIRP | 81892 | 11 | 8 | 21 | |
| GSE54993 | SLIRP | 81892 | 3 | 8 | 59 | |
| GSE54994 | SLIRP | 81892 | 19 | 4 | 30 | |
| GSE60625 | SLIRP | 81892 | 0 | 2 | 9 | |
| GSE74703 | SLIRP | 81892 | 7 | 3 | 26 | |
| GSE74704 | SLIRP | 81892 | 3 | 3 | 14 | |
| TCGA | SLIRP | 81892 | 31 | 16 | 49 |
Total number of gains: 112; Total number of losses: 56; Total Number of normals: 320.
Somatic mutations of SLIRP:
Generating mutation plots.
Highly correlated genes for SLIRP:
Showing top 20/909 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLIRP | PSMC1 | 0.76104 | 8 | 0 | 8 |
| SLIRP | COX16 | 0.75242 | 5 | 0 | 5 |
| SLIRP | EBNA1BP2 | 0.73537 | 3 | 0 | 3 |
| SLIRP | CWC22 | 0.713779 | 3 | 0 | 3 |
| SLIRP | NPHP3 | 0.713609 | 3 | 0 | 3 |
| SLIRP | ANXA7 | 0.703694 | 3 | 0 | 3 |
| SLIRP | XRCC5 | 0.703228 | 3 | 0 | 3 |
| SLIRP | CEBPZ | 0.697818 | 4 | 0 | 3 |
| SLIRP | COPS8 | 0.689629 | 3 | 0 | 3 |
| SLIRP | COCH | 0.681705 | 4 | 0 | 4 |
| SLIRP | C14orf119 | 0.68145 | 4 | 0 | 4 |
| SLIRP | GLRX5 | 0.675474 | 11 | 0 | 10 |
| SLIRP | TRAF7 | 0.67441 | 3 | 0 | 3 |
| SLIRP | PSMA3 | 0.670882 | 9 | 0 | 9 |
| SLIRP | ABHD16B | 0.664937 | 3 | 0 | 3 |
| SLIRP | BCAS4 | 0.662916 | 3 | 0 | 3 |
| SLIRP | UTP23 | 0.660508 | 4 | 0 | 3 |
| SLIRP | YBX1 | 0.659436 | 3 | 0 | 3 |
| SLIRP | RPL8 | 0.65475 | 5 | 0 | 5 |
| SLIRP | SNTA1 | 0.654409 | 3 | 0 | 3 |
For details and further investigation, click here

