| Full name: ribosomal protein L36a like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q21.3 | ||
| Entrez ID: 6166 | HGNC ID: HGNC:10346 | Ensembl Gene: ENSG00000165502 | OMIM ID: 180469 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPL36AL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL36AL | 6166 | 207585_s_at | 0.1007 | 0.9119 | |
| GSE20347 | RPL36AL | 6166 | 207585_s_at | -0.2737 | 0.0525 | |
| GSE23400 | RPL36AL | 6166 | 207585_s_at | 0.0075 | 0.9350 | |
| GSE26886 | RPL36AL | 6166 | 207585_s_at | 0.2770 | 0.1418 | |
| GSE29001 | RPL36AL | 6166 | 207585_s_at | -0.3414 | 0.2171 | |
| GSE38129 | RPL36AL | 6166 | 207585_s_at | -0.2337 | 0.0463 | |
| GSE45670 | RPL36AL | 6166 | 207585_s_at | -0.0135 | 0.9124 | |
| GSE53622 | RPL36AL | 6166 | 26749 | -0.0094 | 0.8832 | |
| GSE53624 | RPL36AL | 6166 | 26749 | 0.1890 | 0.0003 | |
| GSE63941 | RPL36AL | 6166 | 207585_s_at | 0.6203 | 0.0811 | |
| GSE77861 | RPL36AL | 6166 | 207585_s_at | -0.2889 | 0.4869 | |
| GSE97050 | RPL36AL | 6166 | A_24_P159036 | -0.0800 | 0.7401 | |
| SRP007169 | RPL36AL | 6166 | RNAseq | -1.1585 | 0.0016 | |
| SRP008496 | RPL36AL | 6166 | RNAseq | -1.2411 | 0.0000 | |
| SRP064894 | RPL36AL | 6166 | RNAseq | -0.0705 | 0.8232 | |
| SRP133303 | RPL36AL | 6166 | RNAseq | -0.0739 | 0.6592 | |
| SRP159526 | RPL36AL | 6166 | RNAseq | -0.6236 | 0.0427 | |
| SRP193095 | RPL36AL | 6166 | RNAseq | -0.6253 | 0.0000 | |
| SRP219564 | RPL36AL | 6166 | RNAseq | -0.2133 | 0.5367 | |
| TCGA | RPL36AL | 6166 | RNAseq | -0.0974 | 0.0638 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RPL36AL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL36AL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL36AL | 6166 | 7 | 2 | 21 | |
| GSE20123 | RPL36AL | 6166 | 7 | 3 | 20 | |
| GSE43470 | RPL36AL | 6166 | 10 | 1 | 32 | |
| GSE46452 | RPL36AL | 6166 | 16 | 3 | 40 | |
| GSE47630 | RPL36AL | 6166 | 11 | 10 | 19 | |
| GSE54993 | RPL36AL | 6166 | 3 | 9 | 58 | |
| GSE54994 | RPL36AL | 6166 | 19 | 4 | 30 | |
| GSE60625 | RPL36AL | 6166 | 0 | 2 | 9 | |
| GSE74703 | RPL36AL | 6166 | 8 | 1 | 27 | |
| GSE74704 | RPL36AL | 6166 | 2 | 2 | 16 | |
| TCGA | RPL36AL | 6166 | 33 | 13 | 50 |
Total number of gains: 116; Total number of losses: 50; Total Number of normals: 322.
Somatic mutations of RPL36AL:
Generating mutation plots.
Highly correlated genes for RPL36AL:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL36AL | TRAPPC6B | 0.734829 | 4 | 0 | 3 |
| RPL36AL | SLC25A21 | 0.727092 | 3 | 0 | 3 |
| RPL36AL | COX16 | 0.7192 | 5 | 0 | 4 |
| RPL36AL | VAPA | 0.705151 | 3 | 0 | 3 |
| RPL36AL | CEP76 | 0.692516 | 3 | 0 | 3 |
| RPL36AL | CEP63 | 0.679689 | 3 | 0 | 3 |
| RPL36AL | STYX | 0.679455 | 4 | 0 | 3 |
| RPL36AL | MAP4K5 | 0.668006 | 6 | 0 | 6 |
| RPL36AL | AK4 | 0.661921 | 3 | 0 | 3 |
| RPL36AL | HEATR5A | 0.655582 | 4 | 0 | 3 |
| RPL36AL | FLNB | 0.654696 | 3 | 0 | 3 |
| RPL36AL | RORA | 0.647675 | 3 | 0 | 3 |
| RPL36AL | C2orf76 | 0.646978 | 3 | 0 | 3 |
| RPL36AL | SMARCAL1 | 0.646158 | 4 | 0 | 4 |
| RPL36AL | ZNF70 | 0.643051 | 3 | 0 | 3 |
| RPL36AL | WDR89 | 0.642024 | 3 | 0 | 3 |
| RPL36AL | HSD17B12 | 0.640997 | 4 | 0 | 4 |
| RPL36AL | VTI1B | 0.640378 | 11 | 0 | 11 |
| RPL36AL | EIF3E | 0.639611 | 4 | 0 | 3 |
| RPL36AL | MFSD6 | 0.639004 | 3 | 0 | 3 |
For details and further investigation, click here
