| Full name: NOP2/Sun RNA methyltransferase 3 | Alias Symbol: FLJ22609 | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 63899 | HGNC ID: HGNC:26208 | Ensembl Gene: ENSG00000178694 | OMIM ID: 617491 |
| Drug and gene relationship at DGIdb | |||
Expression of NSUN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NSUN3 | 63899 | 219458_s_at | 0.3039 | 0.3079 | |
| GSE20347 | NSUN3 | 63899 | 219458_s_at | 0.4443 | 0.0038 | |
| GSE23400 | NSUN3 | 63899 | 219458_s_at | 0.2318 | 0.0005 | |
| GSE26886 | NSUN3 | 63899 | 219458_s_at | 0.2328 | 0.2892 | |
| GSE29001 | NSUN3 | 63899 | 219458_s_at | 0.3755 | 0.0273 | |
| GSE38129 | NSUN3 | 63899 | 219458_s_at | 0.4367 | 0.0011 | |
| GSE45670 | NSUN3 | 63899 | 219458_s_at | 0.5378 | 0.0007 | |
| GSE53622 | NSUN3 | 63899 | 119155 | 0.5175 | 0.0000 | |
| GSE53624 | NSUN3 | 63899 | 119155 | 0.8244 | 0.0000 | |
| GSE63941 | NSUN3 | 63899 | 219458_s_at | 0.0039 | 0.9944 | |
| GSE77861 | NSUN3 | 63899 | 219458_s_at | 0.1023 | 0.4994 | |
| GSE97050 | NSUN3 | 63899 | A_23_P21785 | 0.2813 | 0.3493 | |
| SRP007169 | NSUN3 | 63899 | RNAseq | -0.3393 | 0.3145 | |
| SRP008496 | NSUN3 | 63899 | RNAseq | 0.0727 | 0.8144 | |
| SRP064894 | NSUN3 | 63899 | RNAseq | 0.3217 | 0.0361 | |
| SRP133303 | NSUN3 | 63899 | RNAseq | 0.3196 | 0.0631 | |
| SRP159526 | NSUN3 | 63899 | RNAseq | 0.2111 | 0.5817 | |
| SRP193095 | NSUN3 | 63899 | RNAseq | 0.3390 | 0.0043 | |
| SRP219564 | NSUN3 | 63899 | RNAseq | 0.3753 | 0.1326 | |
| TCGA | NSUN3 | 63899 | RNAseq | 0.0075 | 0.9309 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NSUN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NSUN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NSUN3 | 63899 | 19 | 1 | 10 | |
| GSE20123 | NSUN3 | 63899 | 18 | 1 | 11 | |
| GSE43470 | NSUN3 | 63899 | 8 | 9 | 26 | |
| GSE46452 | NSUN3 | 63899 | 5 | 15 | 39 | |
| GSE47630 | NSUN3 | 63899 | 14 | 8 | 18 | |
| GSE54993 | NSUN3 | 63899 | 4 | 3 | 63 | |
| GSE54994 | NSUN3 | 63899 | 13 | 16 | 24 | |
| GSE60625 | NSUN3 | 63899 | 0 | 6 | 5 | |
| GSE74703 | NSUN3 | 63899 | 7 | 7 | 22 | |
| GSE74704 | NSUN3 | 63899 | 12 | 1 | 7 | |
| TCGA | NSUN3 | 63899 | 53 | 7 | 36 |
Total number of gains: 153; Total number of losses: 74; Total Number of normals: 261.
Somatic mutations of NSUN3:
Generating mutation plots.
Highly correlated genes for NSUN3:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NSUN3 | MRPS6 | 0.760936 | 3 | 0 | 3 |
| NSUN3 | TTLL4 | 0.759401 | 3 | 0 | 3 |
| NSUN3 | ZNF518B | 0.749637 | 3 | 0 | 3 |
| NSUN3 | ZBTB39 | 0.749205 | 3 | 0 | 3 |
| NSUN3 | CAMKK2 | 0.748411 | 3 | 0 | 3 |
| NSUN3 | MLLT1 | 0.744103 | 3 | 0 | 3 |
| NSUN3 | USE1 | 0.738559 | 3 | 0 | 3 |
| NSUN3 | ANGEL2 | 0.737764 | 3 | 0 | 3 |
| NSUN3 | GPR160 | 0.731631 | 3 | 0 | 3 |
| NSUN3 | C1orf174 | 0.729664 | 3 | 0 | 3 |
| NSUN3 | GLO1 | 0.723975 | 3 | 0 | 3 |
| NSUN3 | COX16 | 0.721749 | 3 | 0 | 3 |
| NSUN3 | WDR5 | 0.7173 | 4 | 0 | 3 |
| NSUN3 | SSR3 | 0.715104 | 5 | 0 | 5 |
| NSUN3 | ELAC2 | 0.714152 | 4 | 0 | 3 |
| NSUN3 | COMMD5 | 0.713513 | 4 | 0 | 3 |
| NSUN3 | PYCR2 | 0.710688 | 3 | 0 | 3 |
| NSUN3 | TMEM237 | 0.70969 | 5 | 0 | 4 |
| NSUN3 | ZNF628 | 0.708697 | 3 | 0 | 3 |
| NSUN3 | TSPAN9 | 0.704226 | 3 | 0 | 3 |
For details and further investigation, click here
