| Full name: transmembrane p24 trafficking protein 10 | Alias Symbol: TMP21|P24(DELTA)|p24d1|p24delta1|p23 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 10972 | HGNC ID: HGNC:16998 | Ensembl Gene: ENSG00000170348 | OMIM ID: 605406 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMED10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED10 | 10972 | 212352_s_at | -0.0658 | 0.9136 | |
| GSE20347 | TMED10 | 10972 | 212352_s_at | -0.3339 | 0.0503 | |
| GSE23400 | TMED10 | 10972 | 212352_s_at | 0.3093 | 0.0000 | |
| GSE26886 | TMED10 | 10972 | 212352_s_at | -0.3011 | 0.1076 | |
| GSE29001 | TMED10 | 10972 | 212352_s_at | -0.0124 | 0.9682 | |
| GSE38129 | TMED10 | 10972 | 212352_s_at | -0.1597 | 0.1967 | |
| GSE45670 | TMED10 | 10972 | 212352_s_at | -0.0247 | 0.8687 | |
| GSE53622 | TMED10 | 10972 | 27916 | 0.2945 | 0.0000 | |
| GSE53624 | TMED10 | 10972 | 86908 | -0.0178 | 0.8660 | |
| GSE63941 | TMED10 | 10972 | 200929_at | 0.3582 | 0.4113 | |
| GSE77861 | TMED10 | 10972 | 200929_at | -0.1465 | 0.7687 | |
| GSE97050 | TMED10 | 10972 | A_24_P917833 | 0.2901 | 0.3568 | |
| SRP007169 | TMED10 | 10972 | RNAseq | -0.8587 | 0.0102 | |
| SRP008496 | TMED10 | 10972 | RNAseq | -0.6095 | 0.0126 | |
| SRP064894 | TMED10 | 10972 | RNAseq | 0.2335 | 0.0981 | |
| SRP133303 | TMED10 | 10972 | RNAseq | 0.3464 | 0.0346 | |
| SRP159526 | TMED10 | 10972 | RNAseq | 0.2204 | 0.4081 | |
| SRP193095 | TMED10 | 10972 | RNAseq | -0.1651 | 0.2502 | |
| SRP219564 | TMED10 | 10972 | RNAseq | 0.4428 | 0.2740 | |
| TCGA | TMED10 | 10972 | RNAseq | -0.0072 | 0.8497 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMED10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED10 | 10972 | 8 | 3 | 19 | |
| GSE20123 | TMED10 | 10972 | 8 | 3 | 19 | |
| GSE43470 | TMED10 | 10972 | 8 | 3 | 32 | |
| GSE46452 | TMED10 | 10972 | 16 | 3 | 40 | |
| GSE47630 | TMED10 | 10972 | 11 | 8 | 21 | |
| GSE54993 | TMED10 | 10972 | 3 | 8 | 59 | |
| GSE54994 | TMED10 | 10972 | 19 | 4 | 30 | |
| GSE60625 | TMED10 | 10972 | 0 | 2 | 9 | |
| GSE74703 | TMED10 | 10972 | 7 | 3 | 26 | |
| GSE74704 | TMED10 | 10972 | 3 | 3 | 14 | |
| TCGA | TMED10 | 10972 | 33 | 16 | 47 |
Total number of gains: 116; Total number of losses: 56; Total Number of normals: 316.
Somatic mutations of TMED10:
Generating mutation plots.
Highly correlated genes for TMED10:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED10 | PDSS2 | 0.797959 | 3 | 0 | 3 |
| TMED10 | ASH2L | 0.772511 | 3 | 0 | 3 |
| TMED10 | RNF144B | 0.72747 | 3 | 0 | 3 |
| TMED10 | COX16 | 0.715339 | 4 | 0 | 3 |
| TMED10 | GFPT1 | 0.708704 | 4 | 0 | 4 |
| TMED10 | ANG | 0.704457 | 3 | 0 | 3 |
| TMED10 | ZFYVE1 | 0.704166 | 3 | 0 | 3 |
| TMED10 | ZBTB9 | 0.701791 | 3 | 0 | 3 |
| TMED10 | USP8 | 0.696442 | 3 | 0 | 3 |
| TMED10 | CLPX | 0.687838 | 3 | 0 | 3 |
| TMED10 | RDH11 | 0.687538 | 5 | 0 | 4 |
| TMED10 | RTN4IP1 | 0.686186 | 3 | 0 | 3 |
| TMED10 | ADAM9 | 0.68451 | 4 | 0 | 3 |
| TMED10 | ELAVL1 | 0.680708 | 3 | 0 | 3 |
| TMED10 | PPCS | 0.677767 | 4 | 0 | 4 |
| TMED10 | USP38 | 0.677737 | 3 | 0 | 3 |
| TMED10 | SEC11A | 0.677366 | 5 | 0 | 4 |
| TMED10 | PGK1 | 0.67142 | 4 | 0 | 4 |
| TMED10 | ATF1 | 0.667476 | 4 | 0 | 3 |
| TMED10 | ACBD3 | 0.665617 | 3 | 0 | 3 |
For details and further investigation, click here
