| Full name: carboxypeptidase A4 | Alias Symbol: CPA3 | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 51200 | HGNC ID: HGNC:15740 | Ensembl Gene: ENSG00000128510 | OMIM ID: 607635 |
| Drug and gene relationship at DGIdb | |||
Expression of CPA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPA4 | 51200 | 205832_at | -0.6516 | 0.4965 | |
| GSE20347 | CPA4 | 51200 | 205832_at | -0.5256 | 0.0191 | |
| GSE23400 | CPA4 | 51200 | 205832_at | -0.3973 | 0.0000 | |
| GSE26886 | CPA4 | 51200 | 205832_at | -1.9325 | 0.0001 | |
| GSE29001 | CPA4 | 51200 | 205832_at | -0.7136 | 0.0155 | |
| GSE38129 | CPA4 | 51200 | 205832_at | -0.4312 | 0.1160 | |
| GSE45670 | CPA4 | 51200 | 205832_at | 0.2391 | 0.4589 | |
| GSE53622 | CPA4 | 51200 | 137594 | -1.0225 | 0.0066 | |
| GSE53624 | CPA4 | 51200 | 137594 | -1.5542 | 0.0000 | |
| GSE63941 | CPA4 | 51200 | 205832_at | -0.2720 | 0.8204 | |
| GSE77861 | CPA4 | 51200 | 205832_at | -1.1916 | 0.0018 | |
| GSE97050 | CPA4 | 51200 | A_23_P19754 | 0.5319 | 0.2765 | |
| SRP007169 | CPA4 | 51200 | RNAseq | -3.8085 | 0.0000 | |
| SRP008496 | CPA4 | 51200 | RNAseq | -3.2991 | 0.0000 | |
| SRP064894 | CPA4 | 51200 | RNAseq | -2.1029 | 0.0000 | |
| SRP133303 | CPA4 | 51200 | RNAseq | -1.3007 | 0.0027 | |
| SRP159526 | CPA4 | 51200 | RNAseq | -2.7905 | 0.0000 | |
| SRP193095 | CPA4 | 51200 | RNAseq | -1.5275 | 0.0003 | |
| SRP219564 | CPA4 | 51200 | RNAseq | -1.4223 | 0.2551 | |
| TCGA | CPA4 | 51200 | RNAseq | 1.3147 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 10.
Survival by CPA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPA4 | 51200 | 8 | 1 | 21 | |
| GSE20123 | CPA4 | 51200 | 8 | 1 | 21 | |
| GSE43470 | CPA4 | 51200 | 2 | 3 | 38 | |
| GSE46452 | CPA4 | 51200 | 7 | 2 | 50 | |
| GSE47630 | CPA4 | 51200 | 7 | 4 | 29 | |
| GSE54993 | CPA4 | 51200 | 3 | 5 | 62 | |
| GSE54994 | CPA4 | 51200 | 7 | 7 | 39 | |
| GSE60625 | CPA4 | 51200 | 0 | 0 | 11 | |
| GSE74703 | CPA4 | 51200 | 2 | 3 | 31 | |
| GSE74704 | CPA4 | 51200 | 4 | 1 | 15 | |
| TCGA | CPA4 | 51200 | 29 | 21 | 46 |
Total number of gains: 77; Total number of losses: 48; Total Number of normals: 363.
Somatic mutations of CPA4:
Generating mutation plots.
Highly correlated genes for CPA4:
Showing top 20/1097 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPA4 | SFTA2 | 0.790839 | 3 | 0 | 3 |
| CPA4 | TMEM161B | 0.739053 | 3 | 0 | 3 |
| CPA4 | DLL1 | 0.729801 | 3 | 0 | 3 |
| CPA4 | LINC00551 | 0.728748 | 3 | 0 | 3 |
| CPA4 | FBXL16 | 0.721834 | 5 | 0 | 5 |
| CPA4 | SLCO2B1 | 0.719584 | 4 | 0 | 4 |
| CPA4 | DCAF12 | 0.708031 | 4 | 0 | 4 |
| CPA4 | WDFY1 | 0.705233 | 3 | 0 | 3 |
| CPA4 | NIPAL1 | 0.703996 | 3 | 0 | 3 |
| CPA4 | RNASE7 | 0.699738 | 7 | 0 | 6 |
| CPA4 | LINC01214 | 0.696032 | 6 | 0 | 6 |
| CPA4 | NCKAP1 | 0.694019 | 3 | 0 | 3 |
| CPA4 | RBM20 | 0.691831 | 3 | 0 | 3 |
| CPA4 | KATNBL1 | 0.690046 | 3 | 0 | 3 |
| CPA4 | IL18 | 0.689988 | 9 | 0 | 9 |
| CPA4 | CEPT1 | 0.686294 | 4 | 0 | 4 |
| CPA4 | C5orf66-AS1 | 0.685625 | 4 | 0 | 4 |
| CPA4 | AIF1L | 0.684792 | 5 | 0 | 4 |
| CPA4 | SLC25A51 | 0.682118 | 3 | 0 | 3 |
| CPA4 | A2ML1 | 0.680874 | 5 | 0 | 5 |
For details and further investigation, click here
