| Full name: ribonuclease A family member 7 | Alias Symbol: RAE1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 84659 | HGNC ID: HGNC:19278 | Ensembl Gene: ENSG00000165799 | OMIM ID: 612484 |
| Drug and gene relationship at DGIdb | |||
Expression of RNASE7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNASE7 | 84659 | 234700_s_at | -1.0664 | 0.4589 | |
| GSE26886 | RNASE7 | 84659 | 233488_at | -3.2428 | 0.0000 | |
| GSE45670 | RNASE7 | 84659 | 234700_s_at | -0.1324 | 0.8804 | |
| GSE53622 | RNASE7 | 84659 | 89202 | -1.5765 | 0.0000 | |
| GSE53624 | RNASE7 | 84659 | 89202 | -2.1710 | 0.0000 | |
| GSE63941 | RNASE7 | 84659 | 234700_s_at | 0.7416 | 0.4326 | |
| GSE77861 | RNASE7 | 84659 | 234700_s_at | -2.2789 | 0.0222 | |
| GSE97050 | RNASE7 | 84659 | A_23_P106080 | 0.1810 | 0.9254 | |
| SRP007169 | RNASE7 | 84659 | RNAseq | -3.8190 | 0.0001 | |
| SRP008496 | RNASE7 | 84659 | RNAseq | -4.1501 | 0.0000 | |
| SRP064894 | RNASE7 | 84659 | RNAseq | -3.3139 | 0.0000 | |
| SRP133303 | RNASE7 | 84659 | RNAseq | -2.1783 | 0.0003 | |
| SRP159526 | RNASE7 | 84659 | RNAseq | -3.4743 | 0.0006 | |
| TCGA | RNASE7 | 84659 | RNAseq | 1.1254 | 0.0200 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by RNASE7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNASE7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNASE7 | 84659 | 9 | 3 | 18 | |
| GSE20123 | RNASE7 | 84659 | 8 | 3 | 19 | |
| GSE43470 | RNASE7 | 84659 | 7 | 1 | 35 | |
| GSE46452 | RNASE7 | 84659 | 19 | 2 | 38 | |
| GSE47630 | RNASE7 | 84659 | 10 | 10 | 20 | |
| GSE54993 | RNASE7 | 84659 | 3 | 11 | 56 | |
| GSE54994 | RNASE7 | 84659 | 18 | 5 | 30 | |
| GSE60625 | RNASE7 | 84659 | 0 | 2 | 9 | |
| GSE74703 | RNASE7 | 84659 | 6 | 1 | 29 | |
| GSE74704 | RNASE7 | 84659 | 4 | 2 | 14 | |
| TCGA | RNASE7 | 84659 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 56; Total Number of normals: 321.
Somatic mutations of RNASE7:
Generating mutation plots.
Highly correlated genes for RNASE7:
Showing top 20/972 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNASE7 | MTMR3 | 0.796816 | 3 | 0 | 3 |
| RNASE7 | SFTA2 | 0.772002 | 3 | 0 | 3 |
| RNASE7 | UPP1 | 0.734077 | 8 | 0 | 8 |
| RNASE7 | CXCR2 | 0.731458 | 6 | 0 | 6 |
| RNASE7 | PLIN3 | 0.731368 | 7 | 0 | 7 |
| RNASE7 | C3orf20 | 0.730806 | 3 | 0 | 3 |
| RNASE7 | CTNNBIP1 | 0.722269 | 4 | 0 | 3 |
| RNASE7 | DAPP1 | 0.721746 | 5 | 0 | 5 |
| RNASE7 | ATG9B | 0.718658 | 7 | 0 | 6 |
| RNASE7 | IL18 | 0.711813 | 7 | 0 | 6 |
| RNASE7 | LINC01214 | 0.711607 | 6 | 0 | 6 |
| RNASE7 | RNF222 | 0.710681 | 3 | 0 | 3 |
| RNASE7 | IFI27L1 | 0.710335 | 3 | 0 | 3 |
| RNASE7 | TMEM79 | 0.709547 | 8 | 0 | 7 |
| RNASE7 | SPRR2D | 0.70546 | 4 | 0 | 4 |
| RNASE7 | SBSN | 0.705239 | 8 | 0 | 8 |
| RNASE7 | ARAP2 | 0.702842 | 3 | 0 | 3 |
| RNASE7 | SLC24A3 | 0.702547 | 5 | 0 | 5 |
| RNASE7 | MXD1 | 0.701562 | 8 | 0 | 6 |
| RNASE7 | CPA4 | 0.699738 | 7 | 0 | 6 |
For details and further investigation, click here
