| Full name: solute carrier organic anion transporter family member 2B1 | Alias Symbol: OATP-B|OATP2B1 | ||
| Type: protein-coding gene | Cytoband: 11q13 | ||
| Entrez ID: 11309 | HGNC ID: HGNC:10962 | Ensembl Gene: ENSG00000137491 | OMIM ID: 604988 |
| Drug and gene relationship at DGIdb | |||
Expression of SLCO2B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLCO2B1 | 11309 | 203473_at | -0.6553 | 0.3780 | |
| GSE20347 | SLCO2B1 | 11309 | 203473_at | -0.6533 | 0.0001 | |
| GSE23400 | SLCO2B1 | 11309 | 203473_at | -0.1366 | 0.0443 | |
| GSE26886 | SLCO2B1 | 11309 | 203473_at | -1.6777 | 0.0000 | |
| GSE29001 | SLCO2B1 | 11309 | 203473_at | -0.3208 | 0.1628 | |
| GSE38129 | SLCO2B1 | 11309 | 203473_at | -0.5864 | 0.0003 | |
| GSE45670 | SLCO2B1 | 11309 | 203473_at | -0.9998 | 0.0001 | |
| GSE53622 | SLCO2B1 | 11309 | 173898 | -0.5578 | 0.0000 | |
| GSE53624 | SLCO2B1 | 11309 | 173898 | -0.7369 | 0.0000 | |
| GSE63941 | SLCO2B1 | 11309 | 211557_x_at | 0.2653 | 0.0691 | |
| GSE77861 | SLCO2B1 | 11309 | 211557_x_at | -0.3716 | 0.0099 | |
| GSE97050 | SLCO2B1 | 11309 | A_23_P150768 | 0.4710 | 0.4395 | |
| SRP007169 | SLCO2B1 | 11309 | RNAseq | 0.2909 | 0.6359 | |
| SRP008496 | SLCO2B1 | 11309 | RNAseq | 0.0168 | 0.9671 | |
| SRP064894 | SLCO2B1 | 11309 | RNAseq | 0.7097 | 0.0383 | |
| SRP133303 | SLCO2B1 | 11309 | RNAseq | 0.0267 | 0.9272 | |
| SRP159526 | SLCO2B1 | 11309 | RNAseq | -0.7250 | 0.2565 | |
| SRP193095 | SLCO2B1 | 11309 | RNAseq | -0.4440 | 0.0371 | |
| SRP219564 | SLCO2B1 | 11309 | RNAseq | 0.9468 | 0.0693 | |
| TCGA | SLCO2B1 | 11309 | RNAseq | -0.1988 | 0.1501 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLCO2B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLCO2B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLCO2B1 | 11309 | 6 | 8 | 16 | |
| GSE20123 | SLCO2B1 | 11309 | 6 | 7 | 17 | |
| GSE43470 | SLCO2B1 | 11309 | 5 | 4 | 34 | |
| GSE46452 | SLCO2B1 | 11309 | 7 | 22 | 30 | |
| GSE47630 | SLCO2B1 | 11309 | 6 | 14 | 20 | |
| GSE54993 | SLCO2B1 | 11309 | 8 | 2 | 60 | |
| GSE54994 | SLCO2B1 | 11309 | 7 | 16 | 30 | |
| GSE60625 | SLCO2B1 | 11309 | 4 | 3 | 4 | |
| GSE74703 | SLCO2B1 | 11309 | 4 | 3 | 29 | |
| GSE74704 | SLCO2B1 | 11309 | 4 | 3 | 13 | |
| TCGA | SLCO2B1 | 11309 | 21 | 33 | 42 |
Total number of gains: 78; Total number of losses: 115; Total Number of normals: 295.
Somatic mutations of SLCO2B1:
Generating mutation plots.
Highly correlated genes for SLCO2B1:
Showing top 20/1179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLCO2B1 | TNFSF8 | 0.757518 | 4 | 0 | 4 |
| SLCO2B1 | GIMAP5 | 0.757283 | 4 | 0 | 4 |
| SLCO2B1 | TBC1D22B | 0.745843 | 3 | 0 | 3 |
| SLCO2B1 | KDM5D | 0.735462 | 3 | 0 | 3 |
| SLCO2B1 | ARHGAP15 | 0.735219 | 4 | 0 | 4 |
| SLCO2B1 | IER3IP1 | 0.734617 | 3 | 0 | 3 |
| SLCO2B1 | SFTA2 | 0.721778 | 4 | 0 | 4 |
| SLCO2B1 | NDFIP2 | 0.720273 | 3 | 0 | 3 |
| SLCO2B1 | CPA4 | 0.719584 | 4 | 0 | 4 |
| SLCO2B1 | GIMAP7 | 0.719172 | 7 | 0 | 6 |
| SLCO2B1 | ZNF844 | 0.711448 | 4 | 0 | 4 |
| SLCO2B1 | UNC5B | 0.708299 | 3 | 0 | 3 |
| SLCO2B1 | ARPC2 | 0.704781 | 6 | 0 | 5 |
| SLCO2B1 | SPNS2 | 0.704353 | 4 | 0 | 4 |
| SLCO2B1 | UTY | 0.703759 | 3 | 0 | 3 |
| SLCO2B1 | GIMAP1 | 0.702965 | 7 | 0 | 6 |
| SLCO2B1 | TIFA | 0.700894 | 6 | 0 | 6 |
| SLCO2B1 | MPEG1 | 0.700398 | 6 | 0 | 6 |
| SLCO2B1 | HOXA2 | 0.69706 | 3 | 0 | 3 |
| SLCO2B1 | ANKRD22 | 0.695394 | 3 | 0 | 3 |
For details and further investigation, click here
