| Full name: collapsin response mediator protein 1 | Alias Symbol: DRP-1|DPYSL1 | ||
| Type: protein-coding gene | Cytoband: 4p16.2 | ||
| Entrez ID: 1400 | HGNC ID: HGNC:2365 | Ensembl Gene: ENSG00000072832 | OMIM ID: 602462 |
| Drug and gene relationship at DGIdb | |||
Expression of CRMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRMP1 | 1400 | 202517_at | 0.0732 | 0.9356 | |
| GSE20347 | CRMP1 | 1400 | 202517_at | 0.2515 | 0.0775 | |
| GSE23400 | CRMP1 | 1400 | 202517_at | 0.1079 | 0.0604 | |
| GSE26886 | CRMP1 | 1400 | 202517_at | 0.4345 | 0.0557 | |
| GSE29001 | CRMP1 | 1400 | 202517_at | -0.0318 | 0.9105 | |
| GSE38129 | CRMP1 | 1400 | 202517_at | 0.3748 | 0.0314 | |
| GSE45670 | CRMP1 | 1400 | 202517_at | 0.2184 | 0.3677 | |
| GSE53622 | CRMP1 | 1400 | 87186 | 0.5359 | 0.0000 | |
| GSE53624 | CRMP1 | 1400 | 87186 | 0.6866 | 0.0000 | |
| GSE63941 | CRMP1 | 1400 | 202517_at | 0.8421 | 0.2920 | |
| GSE77861 | CRMP1 | 1400 | 202517_at | 0.3968 | 0.0791 | |
| GSE97050 | CRMP1 | 1400 | A_23_P132889 | -0.1242 | 0.7013 | |
| SRP007169 | CRMP1 | 1400 | RNAseq | 3.1776 | 0.0005 | |
| SRP008496 | CRMP1 | 1400 | RNAseq | 3.4407 | 0.0000 | |
| SRP064894 | CRMP1 | 1400 | RNAseq | 0.8595 | 0.0009 | |
| SRP133303 | CRMP1 | 1400 | RNAseq | 0.6629 | 0.0112 | |
| SRP159526 | CRMP1 | 1400 | RNAseq | 0.9097 | 0.0105 | |
| SRP193095 | CRMP1 | 1400 | RNAseq | 0.6286 | 0.0013 | |
| SRP219564 | CRMP1 | 1400 | RNAseq | 0.3011 | 0.5053 | |
| TCGA | CRMP1 | 1400 | RNAseq | 0.0866 | 0.6312 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CRMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRMP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRMP1 | 1400 | 0 | 18 | 12 | |
| GSE20123 | CRMP1 | 1400 | 0 | 18 | 12 | |
| GSE43470 | CRMP1 | 1400 | 0 | 17 | 26 | |
| GSE46452 | CRMP1 | 1400 | 1 | 36 | 22 | |
| GSE47630 | CRMP1 | 1400 | 1 | 19 | 20 | |
| GSE54993 | CRMP1 | 1400 | 10 | 0 | 60 | |
| GSE54994 | CRMP1 | 1400 | 3 | 12 | 38 | |
| GSE60625 | CRMP1 | 1400 | 0 | 0 | 11 | |
| GSE74703 | CRMP1 | 1400 | 0 | 13 | 23 | |
| GSE74704 | CRMP1 | 1400 | 0 | 10 | 10 | |
| TCGA | CRMP1 | 1400 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.
Somatic mutations of CRMP1:
Generating mutation plots.
Highly correlated genes for CRMP1:
Showing top 20/296 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRMP1 | ANKRD34A | 0.74055 | 3 | 0 | 3 |
| CRMP1 | ITGB3 | 0.72188 | 3 | 0 | 3 |
| CRMP1 | ZCCHC3 | 0.719653 | 3 | 0 | 3 |
| CRMP1 | KRTAP12-2 | 0.716843 | 3 | 0 | 3 |
| CRMP1 | MMP2 | 0.715059 | 3 | 0 | 3 |
| CRMP1 | CBL | 0.708087 | 3 | 0 | 3 |
| CRMP1 | MAPK8IP3 | 0.696954 | 3 | 0 | 3 |
| CRMP1 | ELP2 | 0.694685 | 3 | 0 | 3 |
| CRMP1 | RNF214 | 0.692335 | 3 | 0 | 3 |
| CRMP1 | MPG | 0.688731 | 4 | 0 | 4 |
| CRMP1 | MYH10 | 0.687137 | 3 | 0 | 3 |
| CRMP1 | ENTPD2 | 0.6836 | 3 | 0 | 3 |
| CRMP1 | TUBB4B | 0.678663 | 3 | 0 | 3 |
| CRMP1 | LRRC55 | 0.668207 | 4 | 0 | 3 |
| CRMP1 | PCBP3 | 0.666619 | 4 | 0 | 4 |
| CRMP1 | PHLDB1 | 0.658755 | 3 | 0 | 3 |
| CRMP1 | HAUS1 | 0.657106 | 3 | 0 | 3 |
| CRMP1 | RIMKLA | 0.656341 | 3 | 0 | 3 |
| CRMP1 | PCDH19 | 0.654703 | 5 | 0 | 5 |
| CRMP1 | PRKACA | 0.652426 | 3 | 0 | 3 |
For details and further investigation, click here
