| Full name: N-methylpurine DNA glycosylase | Alias Symbol: MDG | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 4350 | HGNC ID: HGNC:7211 | Ensembl Gene: ENSG00000103152 | OMIM ID: 156565 |
| Drug and gene relationship at DGIdb | |||
Expression of MPG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPG | 4350 | 203686_at | 0.3296 | 0.2196 | |
| GSE20347 | MPG | 4350 | 203686_at | 0.1851 | 0.0816 | |
| GSE23400 | MPG | 4350 | 203686_at | 0.1864 | 0.0003 | |
| GSE26886 | MPG | 4350 | 203686_at | 0.7376 | 0.0000 | |
| GSE29001 | MPG | 4350 | 203686_at | 0.2063 | 0.1342 | |
| GSE38129 | MPG | 4350 | 203686_at | 0.2297 | 0.0247 | |
| GSE45670 | MPG | 4350 | 203686_at | 0.1727 | 0.1820 | |
| GSE53622 | MPG | 4350 | 78649 | 0.1542 | 0.0098 | |
| GSE53624 | MPG | 4350 | 78649 | 0.2332 | 0.0008 | |
| GSE63941 | MPG | 4350 | 203686_at | -0.4746 | 0.1551 | |
| GSE77861 | MPG | 4350 | 203686_at | 0.2977 | 0.1278 | |
| GSE97050 | MPG | 4350 | A_24_P48162 | 0.5691 | 0.1065 | |
| SRP007169 | MPG | 4350 | RNAseq | -0.4914 | 0.2197 | |
| SRP008496 | MPG | 4350 | RNAseq | -0.5920 | 0.0234 | |
| SRP064894 | MPG | 4350 | RNAseq | 0.6528 | 0.0946 | |
| SRP133303 | MPG | 4350 | RNAseq | 0.3236 | 0.0050 | |
| SRP159526 | MPG | 4350 | RNAseq | 0.3988 | 0.2288 | |
| SRP193095 | MPG | 4350 | RNAseq | 0.0592 | 0.6602 | |
| SRP219564 | MPG | 4350 | RNAseq | 0.3886 | 0.3628 | |
| TCGA | MPG | 4350 | RNAseq | 0.0372 | 0.5546 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPG | 4350 | 5 | 5 | 20 | |
| GSE20123 | MPG | 4350 | 5 | 4 | 21 | |
| GSE43470 | MPG | 4350 | 3 | 7 | 33 | |
| GSE46452 | MPG | 4350 | 38 | 1 | 20 | |
| GSE47630 | MPG | 4350 | 13 | 6 | 21 | |
| GSE54993 | MPG | 4350 | 3 | 5 | 62 | |
| GSE54994 | MPG | 4350 | 4 | 10 | 39 | |
| GSE60625 | MPG | 4350 | 4 | 0 | 7 | |
| GSE74703 | MPG | 4350 | 3 | 5 | 28 | |
| GSE74704 | MPG | 4350 | 3 | 2 | 15 | |
| TCGA | MPG | 4350 | 20 | 15 | 61 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of MPG:
Generating mutation plots.
Highly correlated genes for MPG:
Showing top 20/1041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPG | GMCL1 | 0.784103 | 3 | 0 | 3 |
| MPG | FAM89B | 0.781242 | 3 | 0 | 3 |
| MPG | C12orf65 | 0.775799 | 3 | 0 | 3 |
| MPG | SHANK3 | 0.76239 | 3 | 0 | 3 |
| MPG | CATSPER1 | 0.746581 | 3 | 0 | 3 |
| MPG | STK3 | 0.739048 | 3 | 0 | 3 |
| MPG | MRPL36 | 0.734023 | 4 | 0 | 3 |
| MPG | RHOBTB2 | 0.732256 | 3 | 0 | 3 |
| MPG | PIK3R3 | 0.731281 | 3 | 0 | 3 |
| MPG | FMNL3 | 0.727896 | 5 | 0 | 4 |
| MPG | MAST2 | 0.726237 | 3 | 0 | 3 |
| MPG | GHDC | 0.724506 | 4 | 0 | 4 |
| MPG | POC5 | 0.721156 | 4 | 0 | 4 |
| MPG | ALPK2 | 0.72009 | 3 | 0 | 3 |
| MPG | NEIL2 | 0.714398 | 3 | 0 | 3 |
| MPG | NACC1 | 0.713439 | 4 | 0 | 3 |
| MPG | GSPT2 | 0.712844 | 3 | 0 | 3 |
| MPG | SSBP4 | 0.711989 | 5 | 0 | 5 |
| MPG | TTC30B | 0.709879 | 3 | 0 | 3 |
| MPG | MKNK1 | 0.706417 | 4 | 0 | 3 |
For details and further investigation, click here
