| Full name: ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | Alias Symbol: STZ|SAT3|FLJ11867 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 6484 | HGNC ID: HGNC:10864 | Ensembl Gene: ENSG00000110080 | OMIM ID: 104240 |
| Drug and gene relationship at DGIdb | |||
Expression of ST3GAL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST3GAL4 | 6484 | 203759_at | -1.1024 | 0.0940 | |
| GSE20347 | ST3GAL4 | 6484 | 203759_at | -1.0417 | 0.0000 | |
| GSE23400 | ST3GAL4 | 6484 | 203759_at | -0.9542 | 0.0000 | |
| GSE26886 | ST3GAL4 | 6484 | 203759_at | -1.5312 | 0.0000 | |
| GSE29001 | ST3GAL4 | 6484 | 203759_at | -1.2938 | 0.0000 | |
| GSE38129 | ST3GAL4 | 6484 | 203759_at | -0.9473 | 0.0000 | |
| GSE45670 | ST3GAL4 | 6484 | 203759_at | -0.9852 | 0.0028 | |
| GSE53622 | ST3GAL4 | 6484 | 124015 | -1.4438 | 0.0000 | |
| GSE53624 | ST3GAL4 | 6484 | 124015 | -2.1943 | 0.0000 | |
| GSE63941 | ST3GAL4 | 6484 | 203759_at | -0.0513 | 0.9240 | |
| GSE77861 | ST3GAL4 | 6484 | 203759_at | -1.0230 | 0.0036 | |
| GSE97050 | ST3GAL4 | 6484 | A_24_P181055 | -0.5815 | 0.3408 | |
| SRP007169 | ST3GAL4 | 6484 | RNAseq | -4.4440 | 0.0000 | |
| SRP008496 | ST3GAL4 | 6484 | RNAseq | -4.0095 | 0.0000 | |
| SRP064894 | ST3GAL4 | 6484 | RNAseq | -1.8390 | 0.0000 | |
| SRP133303 | ST3GAL4 | 6484 | RNAseq | -1.7501 | 0.0000 | |
| SRP159526 | ST3GAL4 | 6484 | RNAseq | -1.1980 | 0.0366 | |
| SRP193095 | ST3GAL4 | 6484 | RNAseq | -2.1052 | 0.0000 | |
| SRP219564 | ST3GAL4 | 6484 | RNAseq | -1.7080 | 0.0089 | |
| TCGA | ST3GAL4 | 6484 | RNAseq | 0.0519 | 0.6171 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by ST3GAL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST3GAL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST3GAL4 | 6484 | 0 | 13 | 17 | |
| GSE20123 | ST3GAL4 | 6484 | 0 | 13 | 17 | |
| GSE43470 | ST3GAL4 | 6484 | 2 | 7 | 34 | |
| GSE46452 | ST3GAL4 | 6484 | 3 | 26 | 30 | |
| GSE47630 | ST3GAL4 | 6484 | 2 | 19 | 19 | |
| GSE54993 | ST3GAL4 | 6484 | 10 | 0 | 60 | |
| GSE54994 | ST3GAL4 | 6484 | 5 | 19 | 29 | |
| GSE60625 | ST3GAL4 | 6484 | 0 | 3 | 8 | |
| GSE74703 | ST3GAL4 | 6484 | 1 | 5 | 30 | |
| GSE74704 | ST3GAL4 | 6484 | 0 | 9 | 11 | |
| TCGA | ST3GAL4 | 6484 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of ST3GAL4:
Generating mutation plots.
Highly correlated genes for ST3GAL4:
Showing top 20/1125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST3GAL4 | FNDC4 | 0.84287 | 11 | 0 | 11 |
| ST3GAL4 | PMM1 | 0.833644 | 11 | 0 | 11 |
| ST3GAL4 | GYS2 | 0.831556 | 10 | 0 | 10 |
| ST3GAL4 | SPNS2 | 0.830775 | 4 | 0 | 4 |
| ST3GAL4 | TCP11L2 | 0.822947 | 4 | 0 | 4 |
| ST3GAL4 | GMDS | 0.819716 | 9 | 0 | 9 |
| ST3GAL4 | TRIP10 | 0.814787 | 10 | 0 | 10 |
| ST3GAL4 | RMND5B | 0.813686 | 10 | 0 | 10 |
| ST3GAL4 | SLURP1 | 0.809288 | 11 | 0 | 11 |
| ST3GAL4 | SH3GL1 | 0.807459 | 10 | 0 | 10 |
| ST3GAL4 | IL36A | 0.805871 | 11 | 0 | 11 |
| ST3GAL4 | SPINK7 | 0.801957 | 7 | 0 | 7 |
| ST3GAL4 | PADI1 | 0.800254 | 8 | 0 | 8 |
| ST3GAL4 | C18orf25 | 0.799903 | 10 | 0 | 10 |
| ST3GAL4 | RAET1E | 0.798202 | 7 | 0 | 7 |
| ST3GAL4 | UBL3 | 0.795777 | 11 | 0 | 11 |
| ST3GAL4 | CAPN5 | 0.795079 | 10 | 0 | 10 |
| ST3GAL4 | ESPL1 | 0.792406 | 11 | 0 | 11 |
| ST3GAL4 | SLC16A6 | 0.791633 | 10 | 0 | 10 |
| ST3GAL4 | ECM1 | 0.790735 | 11 | 0 | 11 |
For details and further investigation, click here
