| Full name: crystallin mu | Alias Symbol: DFNA40 | ||
| Type: protein-coding gene | Cytoband: 16p12.2 | ||
| Entrez ID: 1428 | HGNC ID: HGNC:2418 | Ensembl Gene: ENSG00000103316 | OMIM ID: 123740 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYM | 1428 | 205489_at | -0.8198 | 0.0690 | |
| GSE20347 | CRYM | 1428 | 205489_at | -0.6115 | 0.0004 | |
| GSE23400 | CRYM | 1428 | 205489_at | -0.5732 | 0.0000 | |
| GSE26886 | CRYM | 1428 | 205489_at | -1.5206 | 0.0000 | |
| GSE29001 | CRYM | 1428 | 205489_at | -0.7455 | 0.0096 | |
| GSE38129 | CRYM | 1428 | 205489_at | -0.8432 | 0.0000 | |
| GSE45670 | CRYM | 1428 | 205489_at | -0.7332 | 0.0733 | |
| GSE53622 | CRYM | 1428 | 9401 | -2.2493 | 0.0000 | |
| GSE53624 | CRYM | 1428 | 9401 | -2.8622 | 0.0000 | |
| GSE63941 | CRYM | 1428 | 205489_at | -0.1996 | 0.5432 | |
| GSE77861 | CRYM | 1428 | 205489_at | -0.5893 | 0.0201 | |
| GSE97050 | CRYM | 1428 | A_23_P77731 | -0.4641 | 0.2586 | |
| SRP007169 | CRYM | 1428 | RNAseq | -3.9304 | 0.0000 | |
| SRP064894 | CRYM | 1428 | RNAseq | -3.7434 | 0.0000 | |
| SRP133303 | CRYM | 1428 | RNAseq | -2.5639 | 0.0000 | |
| SRP159526 | CRYM | 1428 | RNAseq | -3.4601 | 0.0000 | |
| SRP193095 | CRYM | 1428 | RNAseq | -2.9407 | 0.0000 | |
| TCGA | CRYM | 1428 | RNAseq | -0.5765 | 0.3342 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by CRYM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYM | 1428 | 6 | 3 | 21 | |
| GSE20123 | CRYM | 1428 | 6 | 2 | 22 | |
| GSE43470 | CRYM | 1428 | 3 | 3 | 37 | |
| GSE46452 | CRYM | 1428 | 38 | 1 | 20 | |
| GSE47630 | CRYM | 1428 | 11 | 6 | 23 | |
| GSE54993 | CRYM | 1428 | 3 | 5 | 62 | |
| GSE54994 | CRYM | 1428 | 3 | 10 | 40 | |
| GSE60625 | CRYM | 1428 | 4 | 0 | 7 | |
| GSE74703 | CRYM | 1428 | 3 | 2 | 31 | |
| GSE74704 | CRYM | 1428 | 3 | 1 | 16 | |
| TCGA | CRYM | 1428 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of CRYM:
Generating mutation plots.
Highly correlated genes for CRYM:
Showing top 20/1219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYM | CAPN14 | 0.779499 | 6 | 0 | 6 |
| CRYM | NCCRP1 | 0.769716 | 3 | 0 | 3 |
| CRYM | ATP13A4 | 0.767264 | 7 | 0 | 7 |
| CRYM | SPAG17 | 0.767079 | 5 | 0 | 5 |
| CRYM | PRSS27 | 0.764906 | 7 | 0 | 7 |
| CRYM | KRT78 | 0.762603 | 7 | 0 | 7 |
| CRYM | PLEKHA7 | 0.760625 | 6 | 0 | 6 |
| CRYM | UPK3B | 0.759894 | 3 | 0 | 3 |
| CRYM | VSIG10L | 0.759048 | 7 | 0 | 7 |
| CRYM | FAM3D | 0.758884 | 8 | 0 | 8 |
| CRYM | CEACAM7 | 0.756466 | 11 | 0 | 11 |
| CRYM | ANXA9 | 0.755731 | 11 | 0 | 11 |
| CRYM | TMPRSS11B | 0.75538 | 7 | 0 | 7 |
| CRYM | IL36A | 0.753935 | 11 | 0 | 11 |
| CRYM | SCNN1B | 0.753122 | 11 | 0 | 11 |
| CRYM | GDPD3 | 0.750904 | 11 | 0 | 11 |
| CRYM | SMIM5 | 0.74996 | 6 | 0 | 6 |
| CRYM | TRNP1 | 0.749691 | 7 | 0 | 7 |
| CRYM | CYSRT1 | 0.748928 | 6 | 0 | 6 |
| CRYM | EPS8L1 | 0.745085 | 11 | 0 | 11 |
For details and further investigation, click here
