| Full name: transmembrane protein 26 | Alias Symbol: MGC35010|Em:AC068892.1 | ||
| Type: protein-coding gene | Cytoband: 10q21.2 | ||
| Entrez ID: 219623 | HGNC ID: HGNC:28550 | Ensembl Gene: ENSG00000196932 | OMIM ID: 617803 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM26 | 219623 | 1555025_at | 0.0424 | 0.8928 | |
| GSE26886 | TMEM26 | 219623 | 1555025_at | 0.0250 | 0.8198 | |
| GSE45670 | TMEM26 | 219623 | 1555025_at | 0.0061 | 0.9496 | |
| GSE53622 | TMEM26 | 219623 | 98707 | 0.7806 | 0.0000 | |
| GSE53624 | TMEM26 | 219623 | 98707 | 0.7137 | 0.0000 | |
| GSE63941 | TMEM26 | 219623 | 1555025_at | -0.0403 | 0.7817 | |
| GSE77861 | TMEM26 | 219623 | 1555025_at | -0.0909 | 0.2711 | |
| SRP007169 | TMEM26 | 219623 | RNAseq | 2.5297 | 0.0206 | |
| SRP008496 | TMEM26 | 219623 | RNAseq | 1.3354 | 0.0406 | |
| SRP133303 | TMEM26 | 219623 | RNAseq | 2.3168 | 0.0000 | |
| SRP159526 | TMEM26 | 219623 | RNAseq | 0.9644 | 0.0246 | |
| TCGA | TMEM26 | 219623 | RNAseq | 1.7378 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by TMEM26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM26 | 219623 | 2 | 7 | 21 | |
| GSE20123 | TMEM26 | 219623 | 2 | 7 | 21 | |
| GSE43470 | TMEM26 | 219623 | 2 | 5 | 36 | |
| GSE46452 | TMEM26 | 219623 | 0 | 11 | 48 | |
| GSE47630 | TMEM26 | 219623 | 4 | 12 | 24 | |
| GSE54993 | TMEM26 | 219623 | 9 | 0 | 61 | |
| GSE54994 | TMEM26 | 219623 | 2 | 10 | 41 | |
| GSE60625 | TMEM26 | 219623 | 0 | 0 | 11 | |
| GSE74703 | TMEM26 | 219623 | 2 | 3 | 31 | |
| GSE74704 | TMEM26 | 219623 | 1 | 5 | 14 | |
| TCGA | TMEM26 | 219623 | 11 | 23 | 62 |
Total number of gains: 35; Total number of losses: 83; Total Number of normals: 370.
Somatic mutations of TMEM26:
Generating mutation plots.
Highly correlated genes for TMEM26:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM26 | KLK3 | 0.770621 | 3 | 0 | 3 |
| TMEM26 | CCZ1 | 0.70962 | 3 | 0 | 3 |
| TMEM26 | CSMD2 | 0.705649 | 4 | 0 | 4 |
| TMEM26 | BGN | 0.673285 | 3 | 0 | 3 |
| TMEM26 | ARSI | 0.663006 | 3 | 0 | 3 |
| TMEM26 | CLEC11A | 0.659353 | 3 | 0 | 3 |
| TMEM26 | ZFP92 | 0.657333 | 4 | 0 | 3 |
| TMEM26 | P4HA3 | 0.651736 | 3 | 0 | 3 |
| TMEM26 | PLBD2 | 0.6462 | 3 | 0 | 3 |
| TMEM26 | OSMR | 0.644758 | 3 | 0 | 3 |
| TMEM26 | CFLAR | 0.637742 | 3 | 0 | 3 |
| TMEM26 | CCL25 | 0.634478 | 3 | 0 | 3 |
| TMEM26 | DNAH17-AS1 | 0.630967 | 3 | 0 | 3 |
| TMEM26 | COL5A1 | 0.630502 | 4 | 0 | 3 |
| TMEM26 | ZKSCAN3 | 0.630062 | 3 | 0 | 3 |
| TMEM26 | ANTXR1 | 0.628807 | 3 | 0 | 3 |
| TMEM26 | FNDC1 | 0.618812 | 4 | 0 | 4 |
| TMEM26 | SLC5A12 | 0.618155 | 3 | 0 | 3 |
| TMEM26 | SMAD1-AS2 | 0.617221 | 3 | 0 | 3 |
| TMEM26 | LINC00656 | 0.616362 | 3 | 0 | 3 |
For details and further investigation, click here
