| Full name: fasciculation and elongation protein zeta 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 9637 | HGNC ID: HGNC:3660 | Ensembl Gene: ENSG00000171055 | OMIM ID: 604826 |
| Drug and gene relationship at DGIdb | |||
Expression of FEZ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FEZ2 | 9637 | 215000_s_at | -0.1534 | 0.8057 | |
| GSE20347 | FEZ2 | 9637 | 215000_s_at | 0.0400 | 0.8760 | |
| GSE23400 | FEZ2 | 9637 | 215000_s_at | 0.2946 | 0.0002 | |
| GSE26886 | FEZ2 | 9637 | 215000_s_at | 0.5481 | 0.0149 | |
| GSE29001 | FEZ2 | 9637 | 215000_s_at | 0.3559 | 0.0592 | |
| GSE38129 | FEZ2 | 9637 | 215000_s_at | -0.1041 | 0.6618 | |
| GSE45670 | FEZ2 | 9637 | 215000_s_at | -0.1843 | 0.3246 | |
| GSE53622 | FEZ2 | 9637 | 26963 | -0.0569 | 0.3906 | |
| GSE53624 | FEZ2 | 9637 | 26963 | 0.0161 | 0.7598 | |
| GSE63941 | FEZ2 | 9637 | 215000_s_at | -0.9660 | 0.0386 | |
| GSE77861 | FEZ2 | 9637 | 215000_s_at | 0.7728 | 0.0140 | |
| GSE97050 | FEZ2 | 9637 | A_33_P3311956 | -0.2478 | 0.3675 | |
| SRP007169 | FEZ2 | 9637 | RNAseq | 0.6604 | 0.0522 | |
| SRP008496 | FEZ2 | 9637 | RNAseq | 0.7638 | 0.0017 | |
| SRP064894 | FEZ2 | 9637 | RNAseq | 0.1306 | 0.2668 | |
| SRP133303 | FEZ2 | 9637 | RNAseq | 0.2061 | 0.0435 | |
| SRP159526 | FEZ2 | 9637 | RNAseq | -0.1069 | 0.4766 | |
| SRP193095 | FEZ2 | 9637 | RNAseq | 0.2108 | 0.0835 | |
| SRP219564 | FEZ2 | 9637 | RNAseq | -0.2358 | 0.6402 | |
| TCGA | FEZ2 | 9637 | RNAseq | -0.1176 | 0.0201 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FEZ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FEZ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FEZ2 | 9637 | 10 | 1 | 19 | |
| GSE20123 | FEZ2 | 9637 | 8 | 1 | 21 | |
| GSE43470 | FEZ2 | 9637 | 3 | 0 | 40 | |
| GSE46452 | FEZ2 | 9637 | 1 | 4 | 54 | |
| GSE47630 | FEZ2 | 9637 | 7 | 0 | 33 | |
| GSE54993 | FEZ2 | 9637 | 0 | 5 | 65 | |
| GSE54994 | FEZ2 | 9637 | 10 | 0 | 43 | |
| GSE60625 | FEZ2 | 9637 | 0 | 3 | 8 | |
| GSE74703 | FEZ2 | 9637 | 3 | 0 | 33 | |
| GSE74704 | FEZ2 | 9637 | 8 | 1 | 11 | |
| TCGA | FEZ2 | 9637 | 35 | 2 | 59 |
Total number of gains: 85; Total number of losses: 17; Total Number of normals: 386.
Somatic mutations of FEZ2:
Generating mutation plots.
Highly correlated genes for FEZ2:
Showing top 20/909 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FEZ2 | IRF2BPL | 0.833945 | 3 | 0 | 3 |
| FEZ2 | EID3 | 0.749412 | 3 | 0 | 3 |
| FEZ2 | NRM | 0.747945 | 3 | 0 | 3 |
| FEZ2 | SNF8 | 0.743878 | 3 | 0 | 3 |
| FEZ2 | NEDD1 | 0.743187 | 3 | 0 | 3 |
| FEZ2 | PARM1 | 0.740892 | 3 | 0 | 3 |
| FEZ2 | CTSF | 0.736202 | 3 | 0 | 3 |
| FEZ2 | SLC45A4 | 0.734088 | 3 | 0 | 3 |
| FEZ2 | CPSF3 | 0.734052 | 3 | 0 | 3 |
| FEZ2 | SOCS4 | 0.728508 | 3 | 0 | 3 |
| FEZ2 | LDLR | 0.724969 | 3 | 0 | 3 |
| FEZ2 | GGNBP2 | 0.712442 | 3 | 0 | 3 |
| FEZ2 | DCBLD1 | 0.712251 | 3 | 0 | 3 |
| FEZ2 | ORAI3 | 0.709915 | 3 | 0 | 3 |
| FEZ2 | TLK2 | 0.707267 | 4 | 0 | 4 |
| FEZ2 | CYP27C1 | 0.7033 | 3 | 0 | 3 |
| FEZ2 | TK2 | 0.69928 | 3 | 0 | 3 |
| FEZ2 | STRN3 | 0.698864 | 6 | 0 | 5 |
| FEZ2 | SH3PXD2B | 0.691598 | 3 | 0 | 3 |
| FEZ2 | ATXN10 | 0.687389 | 3 | 0 | 3 |
For details and further investigation, click here
