| Full name: NADH:ubiquinone oxidoreductase subunit B2 | Alias Symbol: AGGG|CI-AGGG | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 4708 | HGNC ID: HGNC:7697 | Ensembl Gene: ENSG00000090266 | OMIM ID: 603838 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB2 | 4708 | 218200_s_at | -0.4788 | 0.2530 | |
| GSE20347 | NDUFB2 | 4708 | 218200_s_at | 0.0486 | 0.7817 | |
| GSE23400 | NDUFB2 | 4708 | 218200_s_at | -0.1135 | 0.1395 | |
| GSE26886 | NDUFB2 | 4708 | 218200_s_at | -0.2898 | 0.0649 | |
| GSE29001 | NDUFB2 | 4708 | 218200_s_at | -0.1327 | 0.7246 | |
| GSE38129 | NDUFB2 | 4708 | 218200_s_at | -0.0154 | 0.9295 | |
| GSE45670 | NDUFB2 | 4708 | 218200_s_at | -0.0027 | 0.9892 | |
| GSE53622 | NDUFB2 | 4708 | 72545 | -0.4217 | 0.0000 | |
| GSE53624 | NDUFB2 | 4708 | 72545 | -0.0225 | 0.7598 | |
| GSE63941 | NDUFB2 | 4708 | 218200_s_at | -0.5230 | 0.1337 | |
| GSE77861 | NDUFB2 | 4708 | 218200_s_at | -0.0033 | 0.9889 | |
| GSE97050 | NDUFB2 | 4708 | A_24_P406301 | -0.4151 | 0.2763 | |
| SRP007169 | NDUFB2 | 4708 | RNAseq | -0.4427 | 0.1665 | |
| SRP008496 | NDUFB2 | 4708 | RNAseq | -0.3894 | 0.0423 | |
| SRP064894 | NDUFB2 | 4708 | RNAseq | 0.1840 | 0.5492 | |
| SRP133303 | NDUFB2 | 4708 | RNAseq | -0.0583 | 0.6661 | |
| SRP159526 | NDUFB2 | 4708 | RNAseq | -0.3210 | 0.1756 | |
| SRP193095 | NDUFB2 | 4708 | RNAseq | -0.7817 | 0.0000 | |
| SRP219564 | NDUFB2 | 4708 | RNAseq | -0.7191 | 0.0960 | |
| TCGA | NDUFB2 | 4708 | RNAseq | -0.1341 | 0.0280 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB2 | 4708 | 5 | 2 | 23 | |
| GSE20123 | NDUFB2 | 4708 | 5 | 2 | 23 | |
| GSE43470 | NDUFB2 | 4708 | 2 | 4 | 37 | |
| GSE46452 | NDUFB2 | 4708 | 7 | 2 | 50 | |
| GSE47630 | NDUFB2 | 4708 | 7 | 4 | 29 | |
| GSE54993 | NDUFB2 | 4708 | 3 | 5 | 62 | |
| GSE54994 | NDUFB2 | 4708 | 5 | 8 | 40 | |
| GSE60625 | NDUFB2 | 4708 | 0 | 0 | 11 | |
| GSE74703 | NDUFB2 | 4708 | 2 | 4 | 30 | |
| GSE74704 | NDUFB2 | 4708 | 1 | 2 | 17 | |
| TCGA | NDUFB2 | 4708 | 28 | 23 | 45 |
Total number of gains: 65; Total number of losses: 56; Total Number of normals: 367.
Somatic mutations of NDUFB2:
Generating mutation plots.
Highly correlated genes for NDUFB2:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB2 | CDC26 | 0.790844 | 3 | 0 | 3 |
| NDUFB2 | VCL | 0.778544 | 3 | 0 | 3 |
| NDUFB2 | ANGPTL1 | 0.749129 | 3 | 0 | 3 |
| NDUFB2 | SORCS1 | 0.736698 | 3 | 0 | 3 |
| NDUFB2 | PPP1R12A | 0.734418 | 4 | 0 | 4 |
| NDUFB2 | UBXN10 | 0.734309 | 3 | 0 | 3 |
| NDUFB2 | DCTN2 | 0.730728 | 3 | 0 | 3 |
| NDUFB2 | DIS3L | 0.706904 | 3 | 0 | 3 |
| NDUFB2 | CTSF | 0.705254 | 4 | 0 | 4 |
| NDUFB2 | NDUFS1 | 0.705147 | 3 | 0 | 3 |
| NDUFB2 | PI16 | 0.704639 | 3 | 0 | 3 |
| NDUFB2 | SCRG1 | 0.700992 | 3 | 0 | 3 |
| NDUFB2 | FILIP1L | 0.699575 | 4 | 0 | 4 |
| NDUFB2 | PLAC9 | 0.695887 | 3 | 0 | 3 |
| NDUFB2 | NFIA | 0.691312 | 3 | 0 | 3 |
| NDUFB2 | MAMDC2 | 0.69123 | 4 | 0 | 3 |
| NDUFB2 | TSPO | 0.690842 | 3 | 0 | 3 |
| NDUFB2 | GPD1L | 0.689158 | 4 | 0 | 4 |
| NDUFB2 | PBX1 | 0.684694 | 5 | 0 | 4 |
| NDUFB2 | RBPMS2 | 0.681914 | 3 | 0 | 3 |
For details and further investigation, click here
