Full name: histidine decarboxylase	Alias Symbol:
Type: protein-coding gene	Cytoband: 15q21.2
Entrez ID: 3067	HGNC ID: HGNC:4855	Ensembl Gene: ENSG00000140287	OMIM ID: 142704
Related drugs: LIXIVAPTAN, OMEPRAZOLE... [more]

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Expression of HDC:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	HDC	3067	207067_s_at	-0.4558	0.4296	Show
GSE20347	HDC	3067	207067_s_at	-0.1526	0.1314	Show
GSE23400	HDC	3067	207067_s_at	-0.2252	0.0000	Show
GSE26886	HDC	3067	207067_s_at	0.0746	0.6771	Show
GSE29001	HDC	3067	207067_s_at	-0.2780	0.2204	Show
GSE38129	HDC	3067	207067_s_at	-0.3593	0.0027	Show
GSE45670	HDC	3067	207067_s_at	-0.8757	0.0017	Show
GSE53622	HDC	3067	14220	-0.9443	0.0000	Show
GSE53624	HDC	3067	14220	-1.0034	0.0000	Show
GSE63941	HDC	3067	207067_s_at	0.0296	0.8958	Show
GSE77861	HDC	3067	207067_s_at	-0.2171	0.0308	Show
GSE97050	HDC	3067	A_23_P117662	0.2567	0.5619	Show
SRP064894	HDC	3067	RNAseq	-0.9192	0.0582	Show
SRP133303	HDC	3067	RNAseq	-1.9480	0.0001	Show
SRP159526	HDC	3067	RNAseq	-0.8263	0.2944	Show
SRP219564	HDC	3067	RNAseq	-0.3365	0.6604	Show
TCGA	HDC	3067	RNAseq	-2.4011	0.0000	Show

Upregulated datasets: 0; Downregulated datasets: 3.  Download Data

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Survival by HDC expression:

 

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Copy number change of HDC:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	HDC	3067	5	3	22	Show
GSE20123	HDC	3067	5	3	22	Show
GSE43470	HDC	3067	5	4	34	Show
GSE46452	HDC	3067	3	7	49	Show
GSE47630	HDC	3067	8	10	22	Show
GSE54993	HDC	3067	4	6	60	Show
GSE54994	HDC	3067	5	7	41	Show
GSE60625	HDC	3067	4	0	7	Show
GSE74703	HDC	3067	5	3	28	Show
GSE74704	HDC	3067	2	3	15	Show
TCGA	HDC	3067	9	16	71	Show

Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.  Download Data

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Somatic mutations of HDC:

 

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Highly correlated genes for HDC:

 

Showing top 20/217 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
HDC	ROBO3	0.676472	3	0	3
HDC	POU1F1	0.675103	3	0	3
HDC	CTSG	0.664657	11	0	8
HDC	ZCCHC18	0.651169	3	0	3
HDC	FTHL17	0.64614	3	0	3
HDC	TBXAS1	0.64181	5	0	3
HDC	VSIG2	0.635847	3	0	3
HDC	MS4A2	0.635361	9	0	6
HDC	NOSTRIN	0.627992	4	0	3
HDC	RASSF1	0.627649	4	0	3
HDC	CCR6	0.624641	6	0	4
HDC	CXCR3	0.621686	3	0	3
HDC	ADRA2A	0.620794	7	0	5
HDC	C16orf89	0.620265	5	0	5
HDC	DOCK2	0.619245	4	0	3
HDC	SPATA13	0.618331	3	0	3
HDC	PLCL2	0.617673	4	0	3
HDC	GJD4	0.611761	4	0	3
HDC	PLCXD3	0.608389	6	0	5
HDC	MPZL2	0.607022	4	0	3

For details and further investigation, click here