| Full name: polypyrimidine tract binding protein 3 | Alias Symbol: DKFZp781I1117 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 9991 | HGNC ID: HGNC:10253 | Ensembl Gene: ENSG00000119314 | OMIM ID: 607527 |
Expression of PTBP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTBP3 | 9991 | 224617_at | -0.0274 | 0.9779 | |
| GSE20347 | PTBP3 | 9991 | 214697_s_at | -0.8206 | 0.0030 | |
| GSE23400 | PTBP3 | 9991 | 214697_s_at | 0.1222 | 0.3643 | |
| GSE26886 | PTBP3 | 9991 | 224617_at | -0.0506 | 0.7874 | |
| GSE29001 | PTBP3 | 9991 | 214697_s_at | -0.3765 | 0.2051 | |
| GSE38129 | PTBP3 | 9991 | 214697_s_at | 0.0110 | 0.9825 | |
| GSE45670 | PTBP3 | 9991 | 224617_at | 0.0196 | 0.8936 | |
| GSE53622 | PTBP3 | 9991 | 48593 | -0.1243 | 0.2270 | |
| GSE53624 | PTBP3 | 9991 | 48593 | -0.1121 | 0.1363 | |
| GSE63941 | PTBP3 | 9991 | 224617_at | 1.2610 | 0.0069 | |
| GSE77861 | PTBP3 | 9991 | 224617_at | -0.0449 | 0.8492 | |
| GSE97050 | PTBP3 | 9991 | A_33_P3315929 | 0.7087 | 0.2954 | |
| SRP007169 | PTBP3 | 9991 | RNAseq | -0.5543 | 0.1726 | |
| SRP008496 | PTBP3 | 9991 | RNAseq | -0.6006 | 0.0073 | |
| SRP064894 | PTBP3 | 9991 | RNAseq | 0.0931 | 0.6442 | |
| SRP133303 | PTBP3 | 9991 | RNAseq | 0.0804 | 0.6614 | |
| SRP159526 | PTBP3 | 9991 | RNAseq | -0.4706 | 0.1290 | |
| SRP193095 | PTBP3 | 9991 | RNAseq | -0.3014 | 0.0142 | |
| SRP219564 | PTBP3 | 9991 | RNAseq | -0.3650 | 0.4947 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PTBP3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PTBP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTBP3 | 9991 | 5 | 10 | 15 | |
| GSE20123 | PTBP3 | 9991 | 5 | 10 | 15 | |
| GSE43470 | PTBP3 | 9991 | 4 | 3 | 36 | |
| GSE46452 | PTBP3 | 9991 | 6 | 13 | 40 | |
| GSE47630 | PTBP3 | 9991 | 3 | 16 | 21 | |
| GSE54993 | PTBP3 | 9991 | 3 | 3 | 64 | |
| GSE54994 | PTBP3 | 9991 | 9 | 10 | 34 | |
| GSE60625 | PTBP3 | 9991 | 0 | 0 | 11 | |
| GSE74703 | PTBP3 | 9991 | 4 | 3 | 29 | |
| GSE74704 | PTBP3 | 9991 | 2 | 8 | 10 | |
| TCGA | PTBP3 | 9991 | 26 | 21 | 49 |
Total number of gains: 67; Total number of losses: 97; Total Number of normals: 324.
Somatic mutations of PTBP3:
Generating mutation plots.
Highly correlated genes for PTBP3:
Showing top 20/711 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTBP3 | RNF149 | 0.775792 | 3 | 0 | 3 |
| PTBP3 | AP1S3 | 0.761895 | 4 | 0 | 4 |
| PTBP3 | RIPK3 | 0.746613 | 3 | 0 | 3 |
| PTBP3 | LAD1 | 0.746264 | 7 | 0 | 7 |
| PTBP3 | SLC25A39 | 0.737652 | 4 | 0 | 4 |
| PTBP3 | SGPP2 | 0.728587 | 3 | 0 | 3 |
| PTBP3 | FAM83G | 0.728251 | 4 | 0 | 4 |
| PTBP3 | SYTL1 | 0.724286 | 4 | 0 | 4 |
| PTBP3 | FAM83B | 0.723701 | 6 | 0 | 5 |
| PTBP3 | MARVELD2 | 0.718563 | 5 | 0 | 4 |
| PTBP3 | CDK5R1 | 0.717803 | 7 | 0 | 7 |
| PTBP3 | SLC10A7 | 0.71111 | 3 | 0 | 3 |
| PTBP3 | FAM110A | 0.710269 | 4 | 0 | 3 |
| PTBP3 | HM13 | 0.708796 | 4 | 0 | 3 |
| PTBP3 | SEC23B | 0.703467 | 6 | 0 | 5 |
| PTBP3 | PUSL1 | 0.703022 | 4 | 0 | 4 |
| PTBP3 | CDH1 | 0.701818 | 8 | 0 | 5 |
| PTBP3 | HPSE | 0.697889 | 7 | 0 | 6 |
| PTBP3 | S100A16 | 0.695502 | 3 | 0 | 3 |
| PTBP3 | TXNDC17 | 0.69486 | 4 | 0 | 3 |
For details and further investigation, click here
