| Full name: signal transducing adaptor family member 2 | Alias Symbol: STAP-2|BKS | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 55620 | HGNC ID: HGNC:30430 | Ensembl Gene: ENSG00000178078 | OMIM ID: 607881 |
| Drug and gene relationship at DGIdb | |||
Expression of STAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STAP2 | 55620 | 221610_s_at | -0.0970 | 0.8984 | |
| GSE20347 | STAP2 | 55620 | 221610_s_at | -0.7472 | 0.0000 | |
| GSE23400 | STAP2 | 55620 | 221610_s_at | -0.5924 | 0.0000 | |
| GSE26886 | STAP2 | 55620 | 221610_s_at | -0.1869 | 0.2733 | |
| GSE29001 | STAP2 | 55620 | 221610_s_at | -1.0049 | 0.0011 | |
| GSE38129 | STAP2 | 55620 | 221610_s_at | -0.1092 | 0.7526 | |
| GSE45670 | STAP2 | 55620 | 221610_s_at | -0.0596 | 0.7330 | |
| GSE63941 | STAP2 | 55620 | 221610_s_at | 2.6449 | 0.0051 | |
| GSE77861 | STAP2 | 55620 | 221610_s_at | -0.5543 | 0.0072 | |
| GSE97050 | STAP2 | 55620 | A_23_P382188 | 0.5114 | 0.3458 | |
| SRP007169 | STAP2 | 55620 | RNAseq | -2.2154 | 0.0000 | |
| SRP008496 | STAP2 | 55620 | RNAseq | -2.0674 | 0.0000 | |
| SRP064894 | STAP2 | 55620 | RNAseq | -0.9579 | 0.0064 | |
| SRP133303 | STAP2 | 55620 | RNAseq | -1.0677 | 0.0036 | |
| SRP159526 | STAP2 | 55620 | RNAseq | -1.0341 | 0.0001 | |
| SRP193095 | STAP2 | 55620 | RNAseq | -1.2172 | 0.0000 | |
| SRP219564 | STAP2 | 55620 | RNAseq | -0.6311 | 0.3662 | |
| TCGA | STAP2 | 55620 | RNAseq | 0.4171 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by STAP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of STAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STAP2 | 55620 | 5 | 3 | 22 | |
| GSE20123 | STAP2 | 55620 | 4 | 2 | 24 | |
| GSE43470 | STAP2 | 55620 | 1 | 8 | 34 | |
| GSE46452 | STAP2 | 55620 | 47 | 1 | 11 | |
| GSE47630 | STAP2 | 55620 | 5 | 7 | 28 | |
| GSE54993 | STAP2 | 55620 | 16 | 3 | 51 | |
| GSE54994 | STAP2 | 55620 | 6 | 16 | 31 | |
| GSE60625 | STAP2 | 55620 | 9 | 0 | 2 | |
| GSE74703 | STAP2 | 55620 | 1 | 5 | 30 | |
| GSE74704 | STAP2 | 55620 | 1 | 2 | 17 | |
| TCGA | STAP2 | 55620 | 11 | 18 | 67 |
Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.
Somatic mutations of STAP2:
Generating mutation plots.
Highly correlated genes for STAP2:
Showing top 20/886 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STAP2 | VDR | 0.790126 | 4 | 0 | 4 |
| STAP2 | EPHA1 | 0.754167 | 10 | 0 | 10 |
| STAP2 | CDS1 | 0.745939 | 9 | 0 | 8 |
| STAP2 | MPZL2 | 0.734692 | 8 | 0 | 8 |
| STAP2 | CARD6 | 0.733215 | 3 | 0 | 3 |
| STAP2 | CXADR | 0.729231 | 4 | 0 | 4 |
| STAP2 | SIM2 | 0.727055 | 5 | 0 | 5 |
| STAP2 | PRRG4 | 0.719062 | 8 | 0 | 8 |
| STAP2 | RBM47 | 0.717294 | 9 | 0 | 8 |
| STAP2 | DENND2D | 0.717262 | 8 | 0 | 7 |
| STAP2 | EHF | 0.715378 | 9 | 0 | 8 |
| STAP2 | FBXL5 | 0.714865 | 3 | 0 | 3 |
| STAP2 | VAMP8 | 0.713222 | 9 | 0 | 8 |
| STAP2 | SPINT2 | 0.712539 | 5 | 0 | 4 |
| STAP2 | FAM160A1 | 0.709781 | 4 | 0 | 4 |
| STAP2 | GNA15 | 0.709013 | 9 | 0 | 8 |
| STAP2 | CNPPD1 | 0.707163 | 4 | 0 | 4 |
| STAP2 | SOX15 | 0.704092 | 3 | 0 | 3 |
| STAP2 | ESRP1 | 0.700021 | 9 | 0 | 8 |
| STAP2 | SAMD9 | 0.697671 | 7 | 0 | 7 |
For details and further investigation, click here
