| Full name: CDP-diacylglycerol synthase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.23 | ||
| Entrez ID: 1040 | HGNC ID: HGNC:1800 | Ensembl Gene: ENSG00000163624 | OMIM ID: 603548 |
| Drug and gene relationship at DGIdb | |||
Expression of CDS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDS1 | 1040 | 205709_s_at | -0.1997 | 0.8646 | |
| GSE20347 | CDS1 | 1040 | 205709_s_at | -1.1558 | 0.0000 | |
| GSE23400 | CDS1 | 1040 | 205709_s_at | -0.7970 | 0.0000 | |
| GSE26886 | CDS1 | 1040 | 226185_at | -1.8886 | 0.0000 | |
| GSE29001 | CDS1 | 1040 | 205709_s_at | -1.4726 | 0.0001 | |
| GSE38129 | CDS1 | 1040 | 205709_s_at | -0.5741 | 0.2486 | |
| GSE45670 | CDS1 | 1040 | 226185_at | -0.5834 | 0.0200 | |
| GSE53622 | CDS1 | 1040 | 67821 | -0.9725 | 0.0000 | |
| GSE53624 | CDS1 | 1040 | 67821 | -1.5208 | 0.0000 | |
| GSE63941 | CDS1 | 1040 | 205709_s_at | 4.0486 | 0.0001 | |
| GSE77861 | CDS1 | 1040 | 205709_s_at | -0.8063 | 0.0306 | |
| GSE97050 | CDS1 | 1040 | A_23_P7250 | 0.4447 | 0.5217 | |
| SRP007169 | CDS1 | 1040 | RNAseq | -2.2557 | 0.0000 | |
| SRP008496 | CDS1 | 1040 | RNAseq | -2.1789 | 0.0000 | |
| SRP064894 | CDS1 | 1040 | RNAseq | -2.0559 | 0.0000 | |
| SRP133303 | CDS1 | 1040 | RNAseq | -1.0721 | 0.0000 | |
| SRP159526 | CDS1 | 1040 | RNAseq | -1.7230 | 0.0000 | |
| SRP193095 | CDS1 | 1040 | RNAseq | -1.7503 | 0.0000 | |
| SRP219564 | CDS1 | 1040 | RNAseq | -2.0316 | 0.0144 | |
| TCGA | CDS1 | 1040 | RNAseq | -0.0071 | 0.9421 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by CDS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDS1 | 1040 | 2 | 11 | 17 | |
| GSE20123 | CDS1 | 1040 | 2 | 11 | 17 | |
| GSE43470 | CDS1 | 1040 | 0 | 13 | 30 | |
| GSE46452 | CDS1 | 1040 | 1 | 36 | 22 | |
| GSE47630 | CDS1 | 1040 | 0 | 20 | 20 | |
| GSE54993 | CDS1 | 1040 | 8 | 0 | 62 | |
| GSE54994 | CDS1 | 1040 | 1 | 9 | 43 | |
| GSE60625 | CDS1 | 1040 | 0 | 0 | 11 | |
| GSE74703 | CDS1 | 1040 | 0 | 11 | 25 | |
| GSE74704 | CDS1 | 1040 | 1 | 6 | 13 | |
| TCGA | CDS1 | 1040 | 11 | 34 | 51 |
Total number of gains: 26; Total number of losses: 151; Total Number of normals: 311.
Somatic mutations of CDS1:
Generating mutation plots.
Highly correlated genes for CDS1:
Showing top 20/1331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDS1 | FRMD4B | 0.817503 | 11 | 0 | 11 |
| CDS1 | SNORA68 | 0.815786 | 3 | 0 | 3 |
| CDS1 | MAL2 | 0.809482 | 8 | 0 | 8 |
| CDS1 | RBM47 | 0.797793 | 12 | 0 | 12 |
| CDS1 | VPS4B | 0.791847 | 10 | 0 | 10 |
| CDS1 | MPZL3 | 0.788973 | 7 | 0 | 7 |
| CDS1 | TMEM40 | 0.784417 | 12 | 0 | 12 |
| CDS1 | CLIC3 | 0.784144 | 9 | 0 | 9 |
| CDS1 | IL18 | 0.783554 | 11 | 0 | 11 |
| CDS1 | EPHA1 | 0.783206 | 12 | 0 | 12 |
| CDS1 | C15orf48 | 0.782159 | 7 | 0 | 7 |
| CDS1 | SLK | 0.78064 | 10 | 0 | 10 |
| CDS1 | RANBP9 | 0.779784 | 10 | 0 | 10 |
| CDS1 | EHF | 0.778268 | 12 | 0 | 12 |
| CDS1 | WWC1 | 0.777726 | 12 | 0 | 12 |
| CDS1 | TWF1 | 0.777191 | 9 | 0 | 9 |
| CDS1 | CWH43 | 0.777006 | 10 | 0 | 10 |
| CDS1 | FAM214A | 0.775593 | 5 | 0 | 5 |
| CDS1 | CCNYL1 | 0.775311 | 4 | 0 | 4 |
| CDS1 | RAB11A | 0.773523 | 11 | 0 | 11 |
For details and further investigation, click here
