| Full name: major histocompatibility complex, class I-related | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 3140 | HGNC ID: HGNC:4975 | Ensembl Gene: ENSG00000153029 | OMIM ID: 600764 |
| Drug and gene relationship at DGIdb | |||
Expression of MR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MR1 | 3140 | 235352_at | 0.0354 | 0.9701 | |
| GSE20347 | MR1 | 3140 | 210224_at | 0.2106 | 0.1849 | |
| GSE23400 | MR1 | 3140 | 210223_s_at | -0.1216 | 0.0174 | |
| GSE26886 | MR1 | 3140 | 235352_at | 0.7968 | 0.0966 | |
| GSE29001 | MR1 | 3140 | 210223_s_at | 0.1148 | 0.6554 | |
| GSE38129 | MR1 | 3140 | 210224_at | 0.2176 | 0.0561 | |
| GSE45670 | MR1 | 3140 | 235352_at | -0.0479 | 0.9004 | |
| GSE53622 | MR1 | 3140 | 80959 | 0.2845 | 0.0001 | |
| GSE53624 | MR1 | 3140 | 80959 | 0.1739 | 0.0102 | |
| GSE63941 | MR1 | 3140 | 210223_s_at | 0.3941 | 0.4217 | |
| GSE77861 | MR1 | 3140 | 207566_at | -0.0803 | 0.6508 | |
| GSE97050 | MR1 | 3140 | A_23_P74928 | 0.2036 | 0.5127 | |
| SRP007169 | MR1 | 3140 | RNAseq | -0.2721 | 0.4965 | |
| SRP008496 | MR1 | 3140 | RNAseq | 0.2629 | 0.4417 | |
| SRP064894 | MR1 | 3140 | RNAseq | 0.2336 | 0.0841 | |
| SRP133303 | MR1 | 3140 | RNAseq | 0.3243 | 0.1727 | |
| SRP159526 | MR1 | 3140 | RNAseq | -0.2757 | 0.5031 | |
| SRP193095 | MR1 | 3140 | RNAseq | 0.1841 | 0.0666 | |
| SRP219564 | MR1 | 3140 | RNAseq | 0.5112 | 0.3912 | |
| TCGA | MR1 | 3140 | RNAseq | 0.2750 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MR1 | 3140 | 12 | 0 | 18 | |
| GSE20123 | MR1 | 3140 | 12 | 0 | 18 | |
| GSE43470 | MR1 | 3140 | 7 | 1 | 35 | |
| GSE46452 | MR1 | 3140 | 3 | 1 | 55 | |
| GSE47630 | MR1 | 3140 | 14 | 0 | 26 | |
| GSE54993 | MR1 | 3140 | 0 | 6 | 64 | |
| GSE54994 | MR1 | 3140 | 15 | 0 | 38 | |
| GSE60625 | MR1 | 3140 | 0 | 0 | 11 | |
| GSE74703 | MR1 | 3140 | 7 | 1 | 28 | |
| GSE74704 | MR1 | 3140 | 5 | 0 | 15 | |
| TCGA | MR1 | 3140 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of MR1:
Generating mutation plots.
Highly correlated genes for MR1:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MR1 | CCDC97 | 0.804254 | 3 | 0 | 3 |
| MR1 | RPS23 | 0.736144 | 3 | 0 | 3 |
| MR1 | CYHR1 | 0.731859 | 3 | 0 | 3 |
| MR1 | GLCCI1 | 0.731813 | 3 | 0 | 3 |
| MR1 | PREX1 | 0.709004 | 3 | 0 | 3 |
| MR1 | PRPS1L1 | 0.703677 | 3 | 0 | 3 |
| MR1 | UBASH3A | 0.69903 | 3 | 0 | 3 |
| MR1 | GPR107 | 0.695415 | 3 | 0 | 3 |
| MR1 | GALC | 0.694942 | 3 | 0 | 3 |
| MR1 | RUNX3 | 0.69107 | 3 | 0 | 3 |
| MR1 | CAV3 | 0.68891 | 3 | 0 | 3 |
| MR1 | INPP5D | 0.67877 | 3 | 0 | 3 |
| MR1 | C1orf115 | 0.67549 | 3 | 0 | 3 |
| MR1 | TRIM8 | 0.673914 | 4 | 0 | 3 |
| MR1 | STAT2 | 0.673702 | 3 | 0 | 3 |
| MR1 | TRAF5 | 0.671965 | 3 | 0 | 3 |
| MR1 | STAT5B | 0.671405 | 3 | 0 | 3 |
| MR1 | GRAP2 | 0.670459 | 3 | 0 | 3 |
| MR1 | LILRA4 | 0.668385 | 4 | 0 | 4 |
| MR1 | YY1 | 0.664228 | 3 | 0 | 3 |
For details and further investigation, click here
