| Full name: cysteinyl leukotriene receptor 1 | Alias Symbol: CysLT1|CysLT(1)|CYSLT1R | ||
| Type: protein-coding gene | Cytoband: Xq21.1 | ||
| Entrez ID: 10800 | HGNC ID: HGNC:17451 | Ensembl Gene: ENSG00000173198 | OMIM ID: 300201 |
| Drug and gene relationship at DGIdb | |||
CYSLTR1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway |
Expression of CYSLTR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYSLTR1 | 10800 | 231747_at | -1.3488 | 0.3155 | |
| GSE20347 | CYSLTR1 | 10800 | 216288_at | 0.0531 | 0.4797 | |
| GSE23400 | CYSLTR1 | 10800 | 216288_at | -0.0605 | 0.0016 | |
| GSE26886 | CYSLTR1 | 10800 | 231747_at | -1.3771 | 0.0004 | |
| GSE29001 | CYSLTR1 | 10800 | 216288_at | -0.0558 | 0.6126 | |
| GSE38129 | CYSLTR1 | 10800 | 216288_at | -0.1513 | 0.0519 | |
| GSE45670 | CYSLTR1 | 10800 | 231747_at | -2.0826 | 0.0000 | |
| GSE53622 | CYSLTR1 | 10800 | 18340 | -1.4538 | 0.0000 | |
| GSE53624 | CYSLTR1 | 10800 | 18340 | -1.1725 | 0.0000 | |
| GSE63941 | CYSLTR1 | 10800 | 231747_at | -0.7320 | 0.0693 | |
| GSE77861 | CYSLTR1 | 10800 | 231747_at | -0.1499 | 0.1882 | |
| GSE97050 | CYSLTR1 | 10800 | A_23_P22660 | -0.8981 | 0.2216 | |
| SRP007169 | CYSLTR1 | 10800 | RNAseq | -0.6819 | 0.2059 | |
| SRP064894 | CYSLTR1 | 10800 | RNAseq | 0.2687 | 0.5439 | |
| SRP133303 | CYSLTR1 | 10800 | RNAseq | -1.2628 | 0.0000 | |
| SRP159526 | CYSLTR1 | 10800 | RNAseq | -0.3740 | 0.6602 | |
| SRP193095 | CYSLTR1 | 10800 | RNAseq | -0.7138 | 0.0034 | |
| TCGA | CYSLTR1 | 10800 | RNAseq | -0.7674 | 0.0334 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CYSLTR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYSLTR1:
No record found for this gene.
Somatic mutations of CYSLTR1:
Generating mutation plots.
Highly correlated genes for CYSLTR1:
Showing top 20/1009 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYSLTR1 | SORCS1 | 0.85043 | 4 | 0 | 4 |
| CYSLTR1 | C3orf70 | 0.826485 | 5 | 0 | 5 |
| CYSLTR1 | XKR4 | 0.809896 | 5 | 0 | 5 |
| CYSLTR1 | CYP21A2 | 0.803035 | 3 | 0 | 3 |
| CYSLTR1 | FRMD3 | 0.795679 | 5 | 0 | 5 |
| CYSLTR1 | CLEC3B | 0.792967 | 3 | 0 | 3 |
| CYSLTR1 | RNF150 | 0.791636 | 5 | 0 | 5 |
| CYSLTR1 | MRVI1 | 0.791483 | 6 | 0 | 5 |
| CYSLTR1 | LRFN5 | 0.789085 | 4 | 0 | 4 |
| CYSLTR1 | CPXM2 | 0.773066 | 5 | 0 | 5 |
| CYSLTR1 | FAM124A | 0.773004 | 4 | 0 | 4 |
| CYSLTR1 | CFL2 | 0.769904 | 5 | 0 | 5 |
| CYSLTR1 | DNAJC15 | 0.766741 | 3 | 0 | 3 |
| CYSLTR1 | ANGPTL1 | 0.763852 | 6 | 0 | 5 |
| CYSLTR1 | ASB5 | 0.758987 | 6 | 0 | 5 |
| CYSLTR1 | C1QTNF7 | 0.758713 | 6 | 0 | 6 |
| CYSLTR1 | ANO5 | 0.757396 | 6 | 0 | 5 |
| CYSLTR1 | STARD9 | 0.756984 | 4 | 0 | 4 |
| CYSLTR1 | MAMDC2 | 0.755195 | 6 | 0 | 6 |
| CYSLTR1 | RSPO3 | 0.752452 | 6 | 0 | 5 |
For details and further investigation, click here
