| Full name: plexin domain containing 2 | Alias Symbol: TEM7R|FLJ14623 | ||
| Type: protein-coding gene | Cytoband: 10p12.31 | ||
| Entrez ID: 84898 | HGNC ID: HGNC:21013 | Ensembl Gene: ENSG00000120594 | OMIM ID: 606827 |
| Drug and gene relationship at DGIdb | |||
Expression of PLXDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLXDC2 | 84898 | 226865_at | -1.5090 | 0.1166 | |
| GSE20347 | PLXDC2 | 84898 | 214807_at | -1.4593 | 0.0000 | |
| GSE23400 | PLXDC2 | 84898 | 214807_at | -0.1199 | 0.0404 | |
| GSE26886 | PLXDC2 | 84898 | 226865_at | 0.0560 | 0.8919 | |
| GSE29001 | PLXDC2 | 84898 | 214807_at | -1.3121 | 0.0175 | |
| GSE38129 | PLXDC2 | 84898 | 214807_at | -0.9851 | 0.0001 | |
| GSE45670 | PLXDC2 | 84898 | 226865_at | -1.3062 | 0.0001 | |
| GSE53622 | PLXDC2 | 84898 | 11406 | 0.0188 | 0.8780 | |
| GSE53624 | PLXDC2 | 84898 | 11406 | -0.2151 | 0.0109 | |
| GSE63941 | PLXDC2 | 84898 | 227276_at | -3.8719 | 0.0010 | |
| GSE77861 | PLXDC2 | 84898 | 214807_at | -0.5079 | 0.1589 | |
| GSE97050 | PLXDC2 | 84898 | A_23_P161424 | 0.2234 | 0.6953 | |
| SRP007169 | PLXDC2 | 84898 | RNAseq | 0.6099 | 0.0784 | |
| SRP008496 | PLXDC2 | 84898 | RNAseq | 0.5287 | 0.0772 | |
| SRP064894 | PLXDC2 | 84898 | RNAseq | 0.4233 | 0.1277 | |
| SRP133303 | PLXDC2 | 84898 | RNAseq | 0.1451 | 0.6359 | |
| SRP159526 | PLXDC2 | 84898 | RNAseq | -0.5316 | 0.0447 | |
| SRP193095 | PLXDC2 | 84898 | RNAseq | -0.6914 | 0.0020 | |
| SRP219564 | PLXDC2 | 84898 | RNAseq | -0.0460 | 0.8921 | |
| TCGA | PLXDC2 | 84898 | RNAseq | 0.1657 | 0.1294 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by PLXDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLXDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLXDC2 | 84898 | 6 | 8 | 16 | |
| GSE20123 | PLXDC2 | 84898 | 6 | 7 | 17 | |
| GSE43470 | PLXDC2 | 84898 | 3 | 3 | 37 | |
| GSE46452 | PLXDC2 | 84898 | 1 | 14 | 44 | |
| GSE47630 | PLXDC2 | 84898 | 5 | 15 | 20 | |
| GSE54993 | PLXDC2 | 84898 | 10 | 0 | 60 | |
| GSE54994 | PLXDC2 | 84898 | 4 | 8 | 41 | |
| GSE60625 | PLXDC2 | 84898 | 0 | 0 | 11 | |
| GSE74703 | PLXDC2 | 84898 | 2 | 2 | 32 | |
| GSE74704 | PLXDC2 | 84898 | 1 | 6 | 13 | |
| TCGA | PLXDC2 | 84898 | 18 | 27 | 51 |
Total number of gains: 56; Total number of losses: 90; Total Number of normals: 342.
Somatic mutations of PLXDC2:
Generating mutation plots.
Highly correlated genes for PLXDC2:
Showing top 20/486 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLXDC2 | LRRK2 | 0.751726 | 3 | 0 | 3 |
| PLXDC2 | TTC28 | 0.706387 | 4 | 0 | 3 |
| PLXDC2 | LINC01082 | 0.693725 | 3 | 0 | 3 |
| PLXDC2 | SLC9A9 | 0.693167 | 3 | 0 | 3 |
| PLXDC2 | ACTG2 | 0.682129 | 3 | 0 | 3 |
| PLXDC2 | SMDT1 | 0.681518 | 3 | 0 | 3 |
| PLXDC2 | ADRA2A | 0.679812 | 3 | 0 | 3 |
| PLXDC2 | CCDC6 | 0.671812 | 4 | 0 | 4 |
| PLXDC2 | DCAF10 | 0.667114 | 4 | 0 | 4 |
| PLXDC2 | CNN1 | 0.666391 | 3 | 0 | 3 |
| PLXDC2 | ANKRD44 | 0.666145 | 3 | 0 | 3 |
| PLXDC2 | AK3 | 0.66528 | 3 | 0 | 3 |
| PLXDC2 | DENND4C | 0.661732 | 4 | 0 | 3 |
| PLXDC2 | EIF3L | 0.657254 | 3 | 0 | 3 |
| PLXDC2 | DOK6 | 0.654294 | 3 | 0 | 3 |
| PLXDC2 | GULP1 | 0.653112 | 7 | 0 | 5 |
| PLXDC2 | GSN | 0.652293 | 5 | 0 | 4 |
| PLXDC2 | TFAP2B | 0.650311 | 6 | 0 | 6 |
| PLXDC2 | PARD3 | 0.64995 | 6 | 0 | 6 |
| PLXDC2 | UTRN | 0.649749 | 4 | 0 | 3 |
For details and further investigation, click here
