| Full name: death associated protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p15.2 | ||
| Entrez ID: 1611 | HGNC ID: HGNC:2672 | Ensembl Gene: ENSG00000112977 | OMIM ID: 600954 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAP | 1611 | 201095_at | 0.5770 | 0.2780 | |
| GSE20347 | DAP | 1611 | 201095_at | 0.6669 | 0.0001 | |
| GSE23400 | DAP | 1611 | 201095_at | 0.4660 | 0.0000 | |
| GSE26886 | DAP | 1611 | 201095_at | 0.7657 | 0.0013 | |
| GSE29001 | DAP | 1611 | 201095_at | 0.3946 | 0.0885 | |
| GSE38129 | DAP | 1611 | 201095_at | 0.6105 | 0.0000 | |
| GSE45670 | DAP | 1611 | 201095_at | 0.2590 | 0.1943 | |
| GSE53622 | DAP | 1611 | 47395 | 0.7257 | 0.0000 | |
| GSE53624 | DAP | 1611 | 47395 | 0.7896 | 0.0000 | |
| GSE63941 | DAP | 1611 | 201095_at | -1.4446 | 0.0214 | |
| GSE77861 | DAP | 1611 | 201095_at | 0.4200 | 0.1586 | |
| GSE97050 | DAP | 1611 | A_23_P92687 | 0.6992 | 0.0948 | |
| SRP007169 | DAP | 1611 | RNAseq | 1.4816 | 0.0005 | |
| SRP008496 | DAP | 1611 | RNAseq | 1.9370 | 0.0000 | |
| SRP064894 | DAP | 1611 | RNAseq | 0.3193 | 0.0685 | |
| SRP133303 | DAP | 1611 | RNAseq | 0.7253 | 0.0002 | |
| SRP159526 | DAP | 1611 | RNAseq | 0.5575 | 0.0276 | |
| SRP193095 | DAP | 1611 | RNAseq | 0.1527 | 0.5963 | |
| SRP219564 | DAP | 1611 | RNAseq | 0.9776 | 0.0049 | |
| TCGA | DAP | 1611 | RNAseq | -0.1664 | 0.0023 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by DAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAP | 1611 | 12 | 0 | 18 | |
| GSE20123 | DAP | 1611 | 12 | 0 | 18 | |
| GSE43470 | DAP | 1611 | 18 | 0 | 25 | |
| GSE46452 | DAP | 1611 | 6 | 22 | 31 | |
| GSE47630 | DAP | 1611 | 6 | 11 | 23 | |
| GSE54993 | DAP | 1611 | 5 | 5 | 60 | |
| GSE54994 | DAP | 1611 | 29 | 1 | 23 | |
| GSE60625 | DAP | 1611 | 0 | 0 | 11 | |
| GSE74703 | DAP | 1611 | 14 | 0 | 22 | |
| GSE74704 | DAP | 1611 | 11 | 0 | 9 | |
| TCGA | DAP | 1611 | 58 | 3 | 35 |
Total number of gains: 171; Total number of losses: 42; Total Number of normals: 275.
Somatic mutations of DAP:
Generating mutation plots.
Highly correlated genes for DAP:
Showing top 20/1296 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAP | GTPBP6 | 0.757032 | 3 | 0 | 3 |
| DAP | RBPJ | 0.756989 | 3 | 0 | 3 |
| DAP | SLC35B2 | 0.749185 | 3 | 0 | 3 |
| DAP | GDPD1 | 0.742996 | 3 | 0 | 3 |
| DAP | ALPK2 | 0.735374 | 3 | 0 | 3 |
| DAP | KCNE3 | 0.730924 | 4 | 0 | 4 |
| DAP | CLPTM1L | 0.71999 | 9 | 0 | 8 |
| DAP | TPCN2 | 0.719134 | 3 | 0 | 3 |
| DAP | GNG10 | 0.718848 | 3 | 0 | 3 |
| DAP | TMTC4 | 0.714019 | 4 | 0 | 4 |
| DAP | WDR35 | 0.709229 | 3 | 0 | 3 |
| DAP | RPGR | 0.701744 | 3 | 0 | 3 |
| DAP | OAF | 0.694622 | 4 | 0 | 4 |
| DAP | PATL1 | 0.692775 | 3 | 0 | 3 |
| DAP | CENPV | 0.691701 | 5 | 0 | 4 |
| DAP | COL22A1 | 0.689343 | 4 | 0 | 3 |
| DAP | ZC3HAV1 | 0.689184 | 3 | 0 | 3 |
| DAP | KDELR3 | 0.687668 | 12 | 0 | 11 |
| DAP | CEP170 | 0.687068 | 3 | 0 | 3 |
| DAP | EFHC1 | 0.68669 | 3 | 0 | 3 |
For details and further investigation, click here
