| Full name: collagen type XXII alpha 1 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.23-q24.3 | ||
| Entrez ID: 169044 | HGNC ID: HGNC:22989 | Ensembl Gene: ENSG00000169436 | OMIM ID: 610026 |
| Drug and gene relationship at DGIdb | |||
Expression of COL22A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL22A1 | 169044 | 242326_at | 0.1980 | 0.4939 | |
| GSE26886 | COL22A1 | 169044 | 242326_at | 0.3296 | 0.2160 | |
| GSE45670 | COL22A1 | 169044 | 242326_at | 0.3825 | 0.0653 | |
| GSE53622 | COL22A1 | 169044 | 2196 | 3.0902 | 0.0000 | |
| GSE53624 | COL22A1 | 169044 | 2196 | 2.5705 | 0.0000 | |
| GSE63941 | COL22A1 | 169044 | 242326_at | 0.0361 | 0.8530 | |
| GSE77861 | COL22A1 | 169044 | 242326_at | -0.0836 | 0.4473 | |
| GSE97050 | COL22A1 | 169044 | A_32_P405759 | 1.8659 | 0.1057 | |
| SRP133303 | COL22A1 | 169044 | RNAseq | 4.0517 | 0.0000 | |
| SRP159526 | COL22A1 | 169044 | RNAseq | 3.9873 | 0.0000 | |
| SRP219564 | COL22A1 | 169044 | RNAseq | 4.4004 | 0.0001 | |
| TCGA | COL22A1 | 169044 | RNAseq | 1.2021 | 0.0056 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by COL22A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL22A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL22A1 | 169044 | 16 | 0 | 14 | |
| GSE20123 | COL22A1 | 169044 | 16 | 0 | 14 | |
| GSE43470 | COL22A1 | 169044 | 23 | 1 | 19 | |
| GSE46452 | COL22A1 | 169044 | 27 | 0 | 32 | |
| GSE47630 | COL22A1 | 169044 | 24 | 0 | 16 | |
| GSE54993 | COL22A1 | 169044 | 0 | 25 | 45 | |
| GSE54994 | COL22A1 | 169044 | 39 | 1 | 13 | |
| GSE60625 | COL22A1 | 169044 | 3 | 4 | 4 | |
| GSE74703 | COL22A1 | 169044 | 20 | 0 | 16 | |
| GSE74704 | COL22A1 | 169044 | 11 | 0 | 9 | |
| TCGA | COL22A1 | 169044 | 65 | 2 | 29 |
Total number of gains: 244; Total number of losses: 33; Total Number of normals: 211.
Somatic mutations of COL22A1:
Generating mutation plots.
Highly correlated genes for COL22A1:
Showing top 20/451 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL22A1 | OLFM2 | 0.733904 | 3 | 0 | 3 |
| COL22A1 | IL2RA | 0.708228 | 4 | 0 | 3 |
| COL22A1 | PDPN | 0.706982 | 3 | 0 | 3 |
| COL22A1 | CD5 | 0.705188 | 3 | 0 | 3 |
| COL22A1 | CENPO | 0.694188 | 4 | 0 | 4 |
| COL22A1 | THY1 | 0.691359 | 5 | 0 | 5 |
| COL22A1 | CDH11 | 0.689914 | 5 | 0 | 4 |
| COL22A1 | DAP | 0.689343 | 4 | 0 | 3 |
| COL22A1 | ERCC2 | 0.684712 | 3 | 0 | 3 |
| COL22A1 | ANGPT2 | 0.682685 | 4 | 0 | 4 |
| COL22A1 | ADAMTS14 | 0.681594 | 3 | 0 | 3 |
| COL22A1 | SLC17A9 | 0.677613 | 4 | 0 | 3 |
| COL22A1 | RNF2 | 0.672732 | 3 | 0 | 3 |
| COL22A1 | TNFAIP1 | 0.671297 | 3 | 0 | 3 |
| COL22A1 | PPT1 | 0.67095 | 4 | 0 | 4 |
| COL22A1 | OLR1 | 0.669168 | 3 | 0 | 3 |
| COL22A1 | OLFML2B | 0.669032 | 4 | 0 | 4 |
| COL22A1 | SNX10 | 0.667808 | 5 | 0 | 4 |
| COL22A1 | SNAP47 | 0.667792 | 3 | 0 | 3 |
| COL22A1 | CEP170 | 0.666709 | 3 | 0 | 3 |
For details and further investigation, click here
