| Full name: PAT1 homolog 1, processing body mRNA decay factor | Alias Symbol: FLJ36874|Pat1b | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 219988 | HGNC ID: HGNC:26721 | Ensembl Gene: ENSG00000166889 | OMIM ID: 614660 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PATL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PATL1 | 219988 | 225466_at | 0.1316 | 0.7174 | |
| GSE26886 | PATL1 | 219988 | 225466_at | -0.0174 | 0.9469 | |
| GSE45670 | PATL1 | 219988 | 225466_at | 0.2443 | 0.1346 | |
| GSE53622 | PATL1 | 219988 | 87224 | 0.4136 | 0.0000 | |
| GSE53624 | PATL1 | 219988 | 87224 | 0.4453 | 0.0000 | |
| GSE63941 | PATL1 | 219988 | 225466_at | 0.2753 | 0.6500 | |
| GSE77861 | PATL1 | 219988 | 225466_at | 0.1417 | 0.6632 | |
| GSE97050 | PATL1 | 219988 | A_23_P373079 | 0.4517 | 0.1785 | |
| SRP007169 | PATL1 | 219988 | RNAseq | 1.1810 | 0.0010 | |
| SRP008496 | PATL1 | 219988 | RNAseq | 0.6454 | 0.0152 | |
| SRP064894 | PATL1 | 219988 | RNAseq | 0.3091 | 0.2049 | |
| SRP133303 | PATL1 | 219988 | RNAseq | 0.4957 | 0.0055 | |
| SRP159526 | PATL1 | 219988 | RNAseq | 0.3634 | 0.0465 | |
| SRP193095 | PATL1 | 219988 | RNAseq | 0.6352 | 0.0000 | |
| SRP219564 | PATL1 | 219988 | RNAseq | 0.9012 | 0.0747 | |
| TCGA | PATL1 | 219988 | RNAseq | 0.2293 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PATL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PATL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PATL1 | 219988 | 1 | 5 | 24 | |
| GSE20123 | PATL1 | 219988 | 1 | 5 | 24 | |
| GSE43470 | PATL1 | 219988 | 2 | 5 | 36 | |
| GSE46452 | PATL1 | 219988 | 9 | 4 | 46 | |
| GSE47630 | PATL1 | 219988 | 3 | 8 | 29 | |
| GSE54993 | PATL1 | 219988 | 3 | 0 | 67 | |
| GSE54994 | PATL1 | 219988 | 5 | 6 | 42 | |
| GSE60625 | PATL1 | 219988 | 0 | 3 | 8 | |
| GSE74703 | PATL1 | 219988 | 2 | 3 | 31 | |
| GSE74704 | PATL1 | 219988 | 1 | 4 | 15 | |
| TCGA | PATL1 | 219988 | 12 | 11 | 73 |
Total number of gains: 39; Total number of losses: 54; Total Number of normals: 395.
Somatic mutations of PATL1:
Generating mutation plots.
Highly correlated genes for PATL1:
Showing top 20/540 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PATL1 | PTPN2 | 0.758631 | 3 | 0 | 3 |
| PATL1 | XPNPEP3 | 0.758598 | 3 | 0 | 3 |
| PATL1 | LRRC8C | 0.758077 | 3 | 0 | 3 |
| PATL1 | SAMM50 | 0.749235 | 3 | 0 | 3 |
| PATL1 | C1QBP | 0.736896 | 3 | 0 | 3 |
| PATL1 | COMMD2 | 0.735666 | 3 | 0 | 3 |
| PATL1 | MCCC2 | 0.727925 | 3 | 0 | 3 |
| PATL1 | ZNF267 | 0.718411 | 3 | 0 | 3 |
| PATL1 | DUSP18 | 0.715268 | 3 | 0 | 3 |
| PATL1 | POLR2B | 0.709805 | 3 | 0 | 3 |
| PATL1 | PIP4K2C | 0.701514 | 4 | 0 | 4 |
| PATL1 | EBNA1BP2 | 0.697349 | 3 | 0 | 3 |
| PATL1 | DNAJA3 | 0.694566 | 4 | 0 | 3 |
| PATL1 | DAP | 0.692775 | 3 | 0 | 3 |
| PATL1 | JKAMP | 0.69135 | 4 | 0 | 3 |
| PATL1 | ZW10 | 0.686125 | 3 | 0 | 3 |
| PATL1 | GAS2L1 | 0.685599 | 3 | 0 | 3 |
| PATL1 | DEXI | 0.68542 | 3 | 0 | 3 |
| PATL1 | CSF2 | 0.684798 | 3 | 0 | 3 |
| PATL1 | COQ3 | 0.681408 | 3 | 0 | 3 |
For details and further investigation, click here
