| Full name: DDB1 and CUL4 associated factor 11 | Alias Symbol: PRO2389|GL014 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 80344 | HGNC ID: HGNC:20258 | Ensembl Gene: ENSG00000100897 | OMIM ID: 613317 |
| Drug and gene relationship at DGIdb | |||
Expression of DCAF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCAF11 | 80344 | 201886_at | -0.1472 | 0.7723 | |
| GSE20347 | DCAF11 | 80344 | 201886_at | -0.4661 | 0.0062 | |
| GSE23400 | DCAF11 | 80344 | 201886_at | -0.3094 | 0.0000 | |
| GSE26886 | DCAF11 | 80344 | 201886_at | -1.3949 | 0.0000 | |
| GSE29001 | DCAF11 | 80344 | 201886_at | -0.3515 | 0.1521 | |
| GSE38129 | DCAF11 | 80344 | 201886_at | -0.2793 | 0.0509 | |
| GSE45670 | DCAF11 | 80344 | 201886_at | -0.0706 | 0.6445 | |
| GSE53622 | DCAF11 | 80344 | 61536 | -0.6071 | 0.0000 | |
| GSE53624 | DCAF11 | 80344 | 61536 | -0.6219 | 0.0000 | |
| GSE63941 | DCAF11 | 80344 | 201886_at | 0.4611 | 0.3031 | |
| GSE77861 | DCAF11 | 80344 | 201886_at | -0.2546 | 0.2710 | |
| GSE97050 | DCAF11 | 80344 | A_23_P117424 | 0.0769 | 0.7523 | |
| SRP007169 | DCAF11 | 80344 | RNAseq | -0.6261 | 0.1572 | |
| SRP008496 | DCAF11 | 80344 | RNAseq | -0.8170 | 0.0049 | |
| SRP064894 | DCAF11 | 80344 | RNAseq | -0.2025 | 0.1762 | |
| SRP133303 | DCAF11 | 80344 | RNAseq | -0.3994 | 0.0029 | |
| SRP159526 | DCAF11 | 80344 | RNAseq | -0.5217 | 0.0030 | |
| SRP193095 | DCAF11 | 80344 | RNAseq | -0.6337 | 0.0000 | |
| SRP219564 | DCAF11 | 80344 | RNAseq | -0.5957 | 0.0158 | |
| TCGA | DCAF11 | 80344 | RNAseq | -0.2131 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DCAF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCAF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCAF11 | 80344 | 8 | 3 | 19 | |
| GSE20123 | DCAF11 | 80344 | 8 | 3 | 19 | |
| GSE43470 | DCAF11 | 80344 | 8 | 2 | 33 | |
| GSE46452 | DCAF11 | 80344 | 16 | 2 | 41 | |
| GSE47630 | DCAF11 | 80344 | 11 | 10 | 19 | |
| GSE54993 | DCAF11 | 80344 | 3 | 11 | 56 | |
| GSE54994 | DCAF11 | 80344 | 18 | 5 | 30 | |
| GSE60625 | DCAF11 | 80344 | 0 | 2 | 9 | |
| GSE74703 | DCAF11 | 80344 | 7 | 2 | 27 | |
| GSE74704 | DCAF11 | 80344 | 3 | 2 | 15 | |
| TCGA | DCAF11 | 80344 | 27 | 13 | 56 |
Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.
Somatic mutations of DCAF11:
Generating mutation plots.
Highly correlated genes for DCAF11:
Showing top 20/652 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCAF11 | AASDH | 0.699718 | 4 | 0 | 3 |
| DCAF11 | OSTF1 | 0.66618 | 9 | 0 | 9 |
| DCAF11 | SNRNP200 | 0.659814 | 3 | 0 | 3 |
| DCAF11 | C3orf38 | 0.659273 | 5 | 0 | 4 |
| DCAF11 | PLLP | 0.645822 | 7 | 0 | 7 |
| DCAF11 | CCDC115 | 0.634567 | 5 | 0 | 3 |
| DCAF11 | RIPK3 | 0.629273 | 6 | 0 | 5 |
| DCAF11 | C18orf25 | 0.629245 | 7 | 0 | 7 |
| DCAF11 | MIEF2 | 0.627697 | 4 | 0 | 3 |
| DCAF11 | MAPK3 | 0.622406 | 9 | 0 | 9 |
| DCAF11 | CCDC160 | 0.622014 | 3 | 0 | 3 |
| DCAF11 | BNIPL | 0.621452 | 6 | 0 | 5 |
| DCAF11 | GRN | 0.621201 | 8 | 0 | 6 |
| DCAF11 | SUMF1 | 0.620738 | 3 | 0 | 3 |
| DCAF11 | SMPD2 | 0.620542 | 10 | 0 | 9 |
| DCAF11 | CNPPD1 | 0.619384 | 7 | 0 | 7 |
| DCAF11 | DIAPH1 | 0.619078 | 8 | 0 | 5 |
| DCAF11 | GSKIP | 0.617314 | 5 | 0 | 4 |
| DCAF11 | FKBPL | 0.617302 | 10 | 0 | 7 |
| DCAF11 | LRP10 | 0.61631 | 9 | 0 | 8 |
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