| Full name: plasmolipin | Alias Symbol: PMLP | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 51090 | HGNC ID: HGNC:18553 | Ensembl Gene: ENSG00000102934 | OMIM ID: 600340 |
| Drug and gene relationship at DGIdb | |||
Expression of PLLP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLLP | 51090 | 204519_s_at | -1.3216 | 0.0409 | |
| GSE20347 | PLLP | 51090 | 204519_s_at | -1.1100 | 0.0020 | |
| GSE23400 | PLLP | 51090 | 204519_s_at | -0.6374 | 0.0000 | |
| GSE26886 | PLLP | 51090 | 204519_s_at | -1.4445 | 0.0003 | |
| GSE29001 | PLLP | 51090 | 204519_s_at | -1.0671 | 0.0034 | |
| GSE38129 | PLLP | 51090 | 204519_s_at | -0.7172 | 0.0122 | |
| GSE45670 | PLLP | 51090 | 204519_s_at | -1.1477 | 0.0013 | |
| GSE53622 | PLLP | 51090 | 73510 | -1.9090 | 0.0000 | |
| GSE53624 | PLLP | 51090 | 73510 | -2.1158 | 0.0000 | |
| GSE63941 | PLLP | 51090 | 204519_s_at | 2.5695 | 0.0351 | |
| GSE77861 | PLLP | 51090 | 204519_s_at | -0.8995 | 0.0105 | |
| GSE97050 | PLLP | 51090 | A_23_P43763 | -0.8272 | 0.1084 | |
| SRP007169 | PLLP | 51090 | RNAseq | -1.2344 | 0.0169 | |
| SRP008496 | PLLP | 51090 | RNAseq | -1.3696 | 0.0011 | |
| SRP064894 | PLLP | 51090 | RNAseq | -1.5703 | 0.0000 | |
| SRP133303 | PLLP | 51090 | RNAseq | -1.9572 | 0.0000 | |
| SRP159526 | PLLP | 51090 | RNAseq | -1.5524 | 0.0046 | |
| SRP193095 | PLLP | 51090 | RNAseq | -1.9133 | 0.0000 | |
| SRP219564 | PLLP | 51090 | RNAseq | -0.7633 | 0.3374 | |
| TCGA | PLLP | 51090 | RNAseq | -0.9476 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by PLLP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLLP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLLP | 51090 | 6 | 0 | 24 | |
| GSE20123 | PLLP | 51090 | 6 | 1 | 23 | |
| GSE43470 | PLLP | 51090 | 3 | 6 | 34 | |
| GSE46452 | PLLP | 51090 | 38 | 1 | 20 | |
| GSE47630 | PLLP | 51090 | 10 | 8 | 22 | |
| GSE54993 | PLLP | 51090 | 2 | 4 | 64 | |
| GSE54994 | PLLP | 51090 | 7 | 10 | 36 | |
| GSE60625 | PLLP | 51090 | 4 | 0 | 7 | |
| GSE74703 | PLLP | 51090 | 3 | 3 | 30 | |
| GSE74704 | PLLP | 51090 | 5 | 0 | 15 | |
| TCGA | PLLP | 51090 | 26 | 12 | 58 |
Total number of gains: 110; Total number of losses: 45; Total Number of normals: 333.
Somatic mutations of PLLP:
Generating mutation plots.
Highly correlated genes for PLLP:
Showing top 20/1163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLLP | PHYHD1 | 0.739776 | 7 | 0 | 7 |
| PLLP | SLC10A5 | 0.735131 | 3 | 0 | 3 |
| PLLP | SMIM5 | 0.729553 | 5 | 0 | 5 |
| PLLP | TEAD3 | 0.717767 | 3 | 0 | 3 |
| PLLP | LDHD | 0.716635 | 6 | 0 | 5 |
| PLLP | TCP11L2 | 0.707968 | 5 | 0 | 5 |
| PLLP | MCEE | 0.700402 | 7 | 0 | 7 |
| PLLP | SMDT1 | 0.699292 | 4 | 0 | 4 |
| PLLP | SLC46A2 | 0.697924 | 7 | 0 | 7 |
| PLLP | SNORA68 | 0.696685 | 4 | 0 | 4 |
| PLLP | MGST2 | 0.69627 | 12 | 0 | 11 |
| PLLP | ATP13A4 | 0.696043 | 7 | 0 | 7 |
| PLLP | C5orf66-AS1 | 0.694951 | 6 | 0 | 6 |
| PLLP | MPST | 0.694452 | 9 | 0 | 9 |
| PLLP | CA13 | 0.694334 | 3 | 0 | 3 |
| PLLP | USP54 | 0.693197 | 8 | 0 | 7 |
| PLLP | IL34 | 0.691494 | 4 | 0 | 4 |
| PLLP | FBXL16 | 0.689691 | 7 | 0 | 6 |
| PLLP | SFTA2 | 0.685394 | 4 | 0 | 4 |
| PLLP | CAPNS2 | 0.683393 | 4 | 0 | 3 |
For details and further investigation, click here
