| Full name: osteoclast stimulating factor 1 | Alias Symbol: SH3P2|OSF|bA235O14.1 | ||
| Type: protein-coding gene | Cytoband: 9q21.13 | ||
| Entrez ID: 26578 | HGNC ID: HGNC:8510 | Ensembl Gene: ENSG00000134996 | OMIM ID: 610180 |
| Drug and gene relationship at DGIdb | |||
Expression of OSTF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSTF1 | 26578 | 204479_at | -0.6739 | 0.3039 | |
| GSE20347 | OSTF1 | 26578 | 204479_at | -1.1001 | 0.0000 | |
| GSE23400 | OSTF1 | 26578 | 204479_at | -0.8883 | 0.0000 | |
| GSE26886 | OSTF1 | 26578 | 204479_at | -2.1961 | 0.0000 | |
| GSE29001 | OSTF1 | 26578 | 204479_at | -1.2921 | 0.0047 | |
| GSE38129 | OSTF1 | 26578 | 204479_at | -0.5035 | 0.0827 | |
| GSE45670 | OSTF1 | 26578 | 204479_at | -0.4589 | 0.0227 | |
| GSE53622 | OSTF1 | 26578 | 14983 | -1.0941 | 0.0000 | |
| GSE53624 | OSTF1 | 26578 | 14983 | -1.1046 | 0.0000 | |
| GSE63941 | OSTF1 | 26578 | 204479_at | -0.2569 | 0.7132 | |
| GSE77861 | OSTF1 | 26578 | 204479_at | -0.7838 | 0.0358 | |
| GSE97050 | OSTF1 | 26578 | A_23_P60296 | -0.0423 | 0.9500 | |
| SRP007169 | OSTF1 | 26578 | RNAseq | -1.4676 | 0.0003 | |
| SRP008496 | OSTF1 | 26578 | RNAseq | -1.6909 | 0.0000 | |
| SRP064894 | OSTF1 | 26578 | RNAseq | -0.9721 | 0.0000 | |
| SRP133303 | OSTF1 | 26578 | RNAseq | -1.0844 | 0.0000 | |
| SRP159526 | OSTF1 | 26578 | RNAseq | -1.1165 | 0.0171 | |
| SRP193095 | OSTF1 | 26578 | RNAseq | -1.3381 | 0.0000 | |
| SRP219564 | OSTF1 | 26578 | RNAseq | -1.2519 | 0.0149 | |
| TCGA | OSTF1 | 26578 | RNAseq | 0.1783 | 0.0155 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by OSTF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSTF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSTF1 | 26578 | 6 | 10 | 14 | |
| GSE20123 | OSTF1 | 26578 | 6 | 10 | 14 | |
| GSE43470 | OSTF1 | 26578 | 6 | 5 | 32 | |
| GSE46452 | OSTF1 | 26578 | 6 | 14 | 39 | |
| GSE47630 | OSTF1 | 26578 | 1 | 18 | 21 | |
| GSE54993 | OSTF1 | 26578 | 4 | 1 | 65 | |
| GSE54994 | OSTF1 | 26578 | 4 | 13 | 36 | |
| GSE60625 | OSTF1 | 26578 | 0 | 0 | 11 | |
| GSE74703 | OSTF1 | 26578 | 5 | 4 | 27 | |
| GSE74704 | OSTF1 | 26578 | 3 | 7 | 10 | |
| TCGA | OSTF1 | 26578 | 20 | 29 | 47 |
Total number of gains: 61; Total number of losses: 111; Total Number of normals: 316.
Somatic mutations of OSTF1:
Generating mutation plots.
Highly correlated genes for OSTF1:
Showing top 20/1820 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSTF1 | PRSS27 | 0.832153 | 6 | 0 | 6 |
| OSTF1 | CAPN14 | 0.830592 | 6 | 0 | 6 |
| OSTF1 | CYSRT1 | 0.818825 | 6 | 0 | 6 |
| OSTF1 | SPINK7 | 0.806155 | 6 | 0 | 6 |
| OSTF1 | MFSD5 | 0.802721 | 11 | 0 | 11 |
| OSTF1 | ARHGAP27 | 0.80266 | 8 | 0 | 7 |
| OSTF1 | VSIG10L | 0.801636 | 6 | 0 | 6 |
| OSTF1 | GRPEL2 | 0.796736 | 7 | 0 | 7 |
| OSTF1 | NUAK2 | 0.790255 | 3 | 0 | 3 |
| OSTF1 | CKMT1A | 0.789155 | 3 | 0 | 3 |
| OSTF1 | C15orf62 | 0.788925 | 7 | 0 | 7 |
| OSTF1 | TP53INP2 | 0.787085 | 5 | 0 | 5 |
| OSTF1 | MPZL3 | 0.786898 | 7 | 0 | 7 |
| OSTF1 | SMIM5 | 0.785213 | 6 | 0 | 6 |
| OSTF1 | BNIPL | 0.785189 | 7 | 0 | 6 |
| OSTF1 | RAET1E | 0.783289 | 6 | 0 | 6 |
| OSTF1 | RASSF5 | 0.78272 | 7 | 0 | 7 |
| OSTF1 | RNF141 | 0.78106 | 11 | 0 | 11 |
| OSTF1 | TMPRSS11B | 0.779393 | 6 | 0 | 6 |
| OSTF1 | FLG-AS1 | 0.778641 | 6 | 0 | 6 |
For details and further investigation, click here
