| Full name: potassium two pore domain channel subfamily K member 7 | Alias Symbol: K2p7.1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 10089 | HGNC ID: HGNC:6282 | Ensembl Gene: ENSG00000173338 | OMIM ID: 603940 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNK7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNK7 | 10089 | 224055_x_at | -0.6661 | 0.4015 | |
| GSE20347 | KCNK7 | 10089 | 220412_x_at | -0.4361 | 0.0070 | |
| GSE23400 | KCNK7 | 10089 | 220412_x_at | -0.3588 | 0.0000 | |
| GSE26886 | KCNK7 | 10089 | 224008_s_at | -0.7197 | 0.0008 | |
| GSE29001 | KCNK7 | 10089 | 220412_x_at | -0.5698 | 0.0545 | |
| GSE38129 | KCNK7 | 10089 | 220412_x_at | -0.3401 | 0.0563 | |
| GSE45670 | KCNK7 | 10089 | 224055_x_at | -0.4133 | 0.1536 | |
| GSE53622 | KCNK7 | 10089 | 96953 | -1.3869 | 0.0000 | |
| GSE53624 | KCNK7 | 10089 | 96953 | -1.9197 | 0.0000 | |
| GSE63941 | KCNK7 | 10089 | 220412_x_at | 0.2871 | 0.2276 | |
| GSE77861 | KCNK7 | 10089 | 224055_x_at | -0.7099 | 0.0634 | |
| GSE97050 | KCNK7 | 10089 | A_33_P3213797 | -0.2155 | 0.3366 | |
| SRP007169 | KCNK7 | 10089 | RNAseq | -2.3381 | 0.0015 | |
| SRP008496 | KCNK7 | 10089 | RNAseq | -2.7603 | 0.0000 | |
| SRP064894 | KCNK7 | 10089 | RNAseq | -2.5202 | 0.0000 | |
| SRP133303 | KCNK7 | 10089 | RNAseq | -2.2825 | 0.0000 | |
| SRP159526 | KCNK7 | 10089 | RNAseq | -1.9694 | 0.0067 | |
| SRP219564 | KCNK7 | 10089 | RNAseq | -2.9360 | 0.0000 | |
| TCGA | KCNK7 | 10089 | RNAseq | 0.4580 | 0.1328 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by KCNK7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNK7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNK7 | 10089 | 8 | 5 | 17 | |
| GSE20123 | KCNK7 | 10089 | 8 | 5 | 17 | |
| GSE43470 | KCNK7 | 10089 | 4 | 1 | 38 | |
| GSE46452 | KCNK7 | 10089 | 11 | 3 | 45 | |
| GSE47630 | KCNK7 | 10089 | 7 | 5 | 28 | |
| GSE54993 | KCNK7 | 10089 | 3 | 0 | 67 | |
| GSE54994 | KCNK7 | 10089 | 7 | 5 | 41 | |
| GSE60625 | KCNK7 | 10089 | 0 | 3 | 8 | |
| GSE74703 | KCNK7 | 10089 | 3 | 0 | 33 | |
| GSE74704 | KCNK7 | 10089 | 6 | 3 | 11 | |
| TCGA | KCNK7 | 10089 | 23 | 7 | 66 |
Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.
Somatic mutations of KCNK7:
Generating mutation plots.
Highly correlated genes for KCNK7:
Showing top 20/847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNK7 | HMGB4 | 0.830419 | 3 | 0 | 3 |
| KCNK7 | NCCRP1 | 0.812491 | 3 | 0 | 3 |
| KCNK7 | DCD | 0.783091 | 3 | 0 | 3 |
| KCNK7 | RNF222 | 0.781058 | 3 | 0 | 3 |
| KCNK7 | HES5 | 0.779638 | 4 | 0 | 4 |
| KCNK7 | KPRP | 0.776512 | 3 | 0 | 3 |
| KCNK7 | FAM163B | 0.772331 | 3 | 0 | 3 |
| KCNK7 | SDCBP2 | 0.766405 | 3 | 0 | 3 |
| KCNK7 | OTOP3 | 0.764506 | 3 | 0 | 3 |
| KCNK7 | RDH12 | 0.761803 | 7 | 0 | 6 |
| KCNK7 | SPRR2A | 0.754784 | 3 | 0 | 3 |
| KCNK7 | SPRR2E | 0.748071 | 3 | 0 | 3 |
| KCNK7 | SPRR2F | 0.747098 | 3 | 0 | 3 |
| KCNK7 | NOTO | 0.745284 | 3 | 0 | 3 |
| KCNK7 | SPINK7 | 0.739032 | 7 | 0 | 7 |
| KCNK7 | TMPRSS11A | 0.735534 | 3 | 0 | 3 |
| KCNK7 | CES2 | 0.732954 | 8 | 0 | 8 |
| KCNK7 | C6orf132 | 0.731429 | 6 | 0 | 6 |
| KCNK7 | C3orf20 | 0.725736 | 4 | 0 | 3 |
| KCNK7 | CNFN | 0.724997 | 6 | 0 | 6 |
For details and further investigation, click here
