| Full name: proline rich coiled-coil 1 | Alias Symbol: FLJ32875 | ||
| Type: protein-coding gene | Cytoband: 5q23.2 | ||
| Entrez ID: 133619 | HGNC ID: HGNC:28164 | Ensembl Gene: ENSG00000164244 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRRC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRC1 | 133619 | 224643_at | 0.0238 | 0.9722 | |
| GSE20347 | PRRC1 | 133619 | 221734_at | -0.3443 | 0.0071 | |
| GSE23400 | PRRC1 | 133619 | 221734_at | -0.0100 | 0.8825 | |
| GSE26886 | PRRC1 | 133619 | 224643_at | -0.6288 | 0.0193 | |
| GSE29001 | PRRC1 | 133619 | 221734_at | -0.0983 | 0.7712 | |
| GSE38129 | PRRC1 | 133619 | 221734_at | -0.0762 | 0.5653 | |
| GSE45670 | PRRC1 | 133619 | 224643_at | -0.1897 | 0.1241 | |
| GSE53622 | PRRC1 | 133619 | 115887 | 0.1328 | 0.0052 | |
| GSE53624 | PRRC1 | 133619 | 115887 | 0.1633 | 0.0007 | |
| GSE63941 | PRRC1 | 133619 | 224643_at | -1.3344 | 0.0007 | |
| GSE77861 | PRRC1 | 133619 | 224643_at | -0.5325 | 0.0764 | |
| GSE97050 | PRRC1 | 133619 | A_23_P92948 | 0.4326 | 0.1399 | |
| SRP007169 | PRRC1 | 133619 | RNAseq | 0.0120 | 0.9746 | |
| SRP008496 | PRRC1 | 133619 | RNAseq | 0.0002 | 0.9991 | |
| SRP064894 | PRRC1 | 133619 | RNAseq | 0.3206 | 0.0542 | |
| SRP133303 | PRRC1 | 133619 | RNAseq | 0.4468 | 0.0068 | |
| SRP159526 | PRRC1 | 133619 | RNAseq | -0.1621 | 0.4659 | |
| SRP193095 | PRRC1 | 133619 | RNAseq | -0.3418 | 0.0056 | |
| SRP219564 | PRRC1 | 133619 | RNAseq | 0.2985 | 0.3382 | |
| TCGA | PRRC1 | 133619 | RNAseq | -0.0475 | 0.2895 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRRC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRRC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRC1 | 133619 | 1 | 12 | 17 | |
| GSE20123 | PRRC1 | 133619 | 1 | 12 | 17 | |
| GSE43470 | PRRC1 | 133619 | 3 | 8 | 32 | |
| GSE46452 | PRRC1 | 133619 | 0 | 27 | 32 | |
| GSE47630 | PRRC1 | 133619 | 0 | 21 | 19 | |
| GSE54993 | PRRC1 | 133619 | 9 | 1 | 60 | |
| GSE54994 | PRRC1 | 133619 | 2 | 14 | 37 | |
| GSE60625 | PRRC1 | 133619 | 0 | 0 | 11 | |
| GSE74703 | PRRC1 | 133619 | 2 | 6 | 28 | |
| GSE74704 | PRRC1 | 133619 | 1 | 6 | 13 | |
| TCGA | PRRC1 | 133619 | 2 | 40 | 54 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of PRRC1:
Generating mutation plots.
Highly correlated genes for PRRC1:
Showing top 20/732 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRC1 | MRFAP1L1 | 0.779044 | 3 | 0 | 3 |
| PRRC1 | TNFRSF21 | 0.776824 | 3 | 0 | 3 |
| PRRC1 | TTC39B | 0.772413 | 3 | 0 | 3 |
| PRRC1 | VPS35 | 0.767644 | 3 | 0 | 3 |
| PRRC1 | DHRS7 | 0.754331 | 3 | 0 | 3 |
| PRRC1 | SAMD9L | 0.739647 | 3 | 0 | 3 |
| PRRC1 | METAP2 | 0.735068 | 3 | 0 | 3 |
| PRRC1 | LYSMD3 | 0.727539 | 7 | 0 | 7 |
| PRRC1 | NDFIP2 | 0.724544 | 4 | 0 | 4 |
| PRRC1 | ENC1 | 0.721277 | 3 | 0 | 3 |
| PRRC1 | C6orf62 | 0.718608 | 6 | 0 | 6 |
| PRRC1 | IMPACT | 0.716844 | 3 | 0 | 3 |
| PRRC1 | TMEM161B | 0.716318 | 5 | 0 | 4 |
| PRRC1 | UGP2 | 0.709675 | 4 | 0 | 4 |
| PRRC1 | LY75 | 0.709669 | 3 | 0 | 3 |
| PRRC1 | ZNF92 | 0.70919 | 3 | 0 | 3 |
| PRRC1 | DCUN1D4 | 0.70765 | 3 | 0 | 3 |
| PRRC1 | RIOK2 | 0.707344 | 6 | 0 | 6 |
| PRRC1 | TMEM19 | 0.706371 | 5 | 0 | 4 |
| PRRC1 | CNP | 0.706191 | 3 | 0 | 3 |
For details and further investigation, click here
