| Full name: DET1 and DDB1 associated 1 | Alias Symbol: PCIA1|MGC2594 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 79016 | HGNC ID: HGNC:28360 | Ensembl Gene: ENSG00000130311 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DDA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDA1 | 79016 | 218260_at | 0.3364 | 0.2480 | |
| GSE20347 | DDA1 | 79016 | 218260_at | -0.2676 | 0.1575 | |
| GSE23400 | DDA1 | 79016 | 218260_at | 0.0483 | 0.5418 | |
| GSE26886 | DDA1 | 79016 | 227472_at | 0.2575 | 0.0315 | |
| GSE29001 | DDA1 | 79016 | 218260_at | 0.0651 | 0.7016 | |
| GSE38129 | DDA1 | 79016 | 218260_at | 0.0208 | 0.9172 | |
| GSE45670 | DDA1 | 79016 | 227472_at | 0.2056 | 0.0250 | |
| GSE53622 | DDA1 | 79016 | 13730 | 0.1900 | 0.0038 | |
| GSE53624 | DDA1 | 79016 | 13730 | 0.3604 | 0.0000 | |
| GSE63941 | DDA1 | 79016 | 218260_at | 2.4132 | 0.0001 | |
| GSE77861 | DDA1 | 79016 | 218260_at | 0.2740 | 0.2082 | |
| GSE97050 | DDA1 | 79016 | A_24_P262738 | 0.4584 | 0.1809 | |
| SRP007169 | DDA1 | 79016 | RNAseq | -0.7649 | 0.0452 | |
| SRP008496 | DDA1 | 79016 | RNAseq | -0.4743 | 0.0475 | |
| SRP064894 | DDA1 | 79016 | RNAseq | 0.2093 | 0.2791 | |
| SRP133303 | DDA1 | 79016 | RNAseq | 0.2810 | 0.0630 | |
| SRP159526 | DDA1 | 79016 | RNAseq | -0.0871 | 0.6353 | |
| SRP193095 | DDA1 | 79016 | RNAseq | 0.2186 | 0.0384 | |
| SRP219564 | DDA1 | 79016 | RNAseq | 0.2618 | 0.2575 | |
| TCGA | DDA1 | 79016 | RNAseq | 0.0986 | 0.0441 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DDA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDA1 | 79016 | 4 | 4 | 22 | |
| GSE20123 | DDA1 | 79016 | 3 | 2 | 25 | |
| GSE43470 | DDA1 | 79016 | 2 | 6 | 35 | |
| GSE46452 | DDA1 | 79016 | 47 | 1 | 11 | |
| GSE47630 | DDA1 | 79016 | 4 | 8 | 28 | |
| GSE54993 | DDA1 | 79016 | 15 | 4 | 51 | |
| GSE54994 | DDA1 | 79016 | 6 | 14 | 33 | |
| GSE60625 | DDA1 | 79016 | 9 | 0 | 2 | |
| GSE74703 | DDA1 | 79016 | 2 | 4 | 30 | |
| GSE74704 | DDA1 | 79016 | 0 | 2 | 18 | |
| TCGA | DDA1 | 79016 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of DDA1:
Generating mutation plots.
Highly correlated genes for DDA1:
Showing top 20/649 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDA1 | MRPL38 | 0.755616 | 4 | 0 | 4 |
| DDA1 | TMEM203 | 0.730134 | 3 | 0 | 3 |
| DDA1 | USP5 | 0.727102 | 5 | 0 | 5 |
| DDA1 | DDX11 | 0.722404 | 4 | 0 | 3 |
| DDA1 | MAPK1 | 0.71417 | 3 | 0 | 3 |
| DDA1 | ZNF837 | 0.693983 | 3 | 0 | 3 |
| DDA1 | ZNF771 | 0.683109 | 3 | 0 | 3 |
| DDA1 | RPL18 | 0.68181 | 3 | 0 | 3 |
| DDA1 | RAVER1 | 0.680634 | 5 | 0 | 4 |
| DDA1 | TRAPPC2L | 0.678671 | 3 | 0 | 3 |
| DDA1 | PRELID1 | 0.678546 | 3 | 0 | 3 |
| DDA1 | MRPL12 | 0.677868 | 3 | 0 | 3 |
| DDA1 | ZNF668 | 0.677831 | 5 | 0 | 5 |
| DDA1 | SLC4A2 | 0.672406 | 4 | 0 | 4 |
| DDA1 | ANP32B | 0.671707 | 5 | 0 | 5 |
| DDA1 | SMU1 | 0.670972 | 3 | 0 | 3 |
| DDA1 | MRPL3 | 0.669587 | 3 | 0 | 3 |
| DDA1 | EHMT2 | 0.668117 | 3 | 0 | 3 |
| DDA1 | DNAJC19 | 0.667145 | 3 | 0 | 3 |
| DDA1 | FAM86C1 | 0.666282 | 4 | 0 | 4 |
For details and further investigation, click here
