| Full name: translocase of outer mitochondrial membrane 20 | Alias Symbol: KIAA0016|TOM20|MOM19|MAS20 | ||
| Type: protein-coding gene | Cytoband: 1q42.3 | ||
| Entrez ID: 9804 | HGNC ID: HGNC:20947 | Ensembl Gene: ENSG00000173726 | OMIM ID: 601848 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TOMM20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOMM20 | 9804 | 200662_s_at | 0.4763 | 0.0639 | |
| GSE20347 | TOMM20 | 9804 | 200662_s_at | 0.3769 | 0.0076 | |
| GSE23400 | TOMM20 | 9804 | 200662_s_at | 0.5798 | 0.0000 | |
| GSE26886 | TOMM20 | 9804 | 200662_s_at | 0.5817 | 0.0500 | |
| GSE29001 | TOMM20 | 9804 | 200662_s_at | 0.5386 | 0.1388 | |
| GSE38129 | TOMM20 | 9804 | 200662_s_at | 0.5278 | 0.0000 | |
| GSE45670 | TOMM20 | 9804 | 200662_s_at | -0.1799 | 0.1511 | |
| GSE53622 | TOMM20 | 9804 | 87355 | -0.1550 | 0.0293 | |
| GSE53624 | TOMM20 | 9804 | 87355 | 0.2830 | 0.0000 | |
| GSE63941 | TOMM20 | 9804 | 200662_s_at | 0.0788 | 0.8490 | |
| GSE77861 | TOMM20 | 9804 | 200662_s_at | 0.5555 | 0.0329 | |
| GSE97050 | TOMM20 | A_21_P0013326 | -0.3285 | 0.3615 | ||
| SRP007169 | TOMM20 | 9804 | RNAseq | 0.3406 | 0.3793 | |
| SRP008496 | TOMM20 | 9804 | RNAseq | 0.5538 | 0.0404 | |
| SRP064894 | TOMM20 | 9804 | RNAseq | 0.0693 | 0.6245 | |
| SRP133303 | TOMM20 | 9804 | RNAseq | 0.1582 | 0.3120 | |
| SRP159526 | TOMM20 | 9804 | RNAseq | 0.2826 | 0.4799 | |
| SRP193095 | TOMM20 | 9804 | RNAseq | -0.0313 | 0.7654 | |
| SRP219564 | TOMM20 | 9804 | RNAseq | 0.1605 | 0.4967 | |
| TCGA | TOMM20 | 9804 | RNAseq | 0.0053 | 0.9040 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TOMM20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOMM20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOMM20 | 9804 | 10 | 0 | 20 | |
| GSE20123 | TOMM20 | 9804 | 11 | 0 | 19 | |
| GSE43470 | TOMM20 | 9804 | 8 | 0 | 35 | |
| GSE46452 | TOMM20 | 9804 | 4 | 2 | 53 | |
| GSE47630 | TOMM20 | 9804 | 15 | 0 | 25 | |
| GSE54993 | TOMM20 | 9804 | 0 | 6 | 64 | |
| GSE54994 | TOMM20 | 9804 | 16 | 0 | 37 | |
| GSE60625 | TOMM20 | 9804 | 0 | 0 | 11 | |
| GSE74703 | TOMM20 | 9804 | 8 | 0 | 28 | |
| GSE74704 | TOMM20 | 9804 | 5 | 0 | 15 | |
| TCGA | TOMM20 | 9804 | 44 | 3 | 49 |
Total number of gains: 121; Total number of losses: 11; Total Number of normals: 356.
Somatic mutations of TOMM20:
Generating mutation plots.
Highly correlated genes for TOMM20:
Showing top 20/1502 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOMM20 | SMCR8 | 0.786357 | 4 | 0 | 4 |
| TOMM20 | UHMK1 | 0.770204 | 4 | 0 | 4 |
| TOMM20 | RP9 | 0.768192 | 3 | 0 | 3 |
| TOMM20 | SORL1 | 0.763593 | 3 | 0 | 3 |
| TOMM20 | PPTC7 | 0.746389 | 3 | 0 | 3 |
| TOMM20 | SNRPE | 0.736776 | 9 | 0 | 8 |
| TOMM20 | DDHD1 | 0.728496 | 4 | 0 | 4 |
| TOMM20 | CCDC127 | 0.727329 | 3 | 0 | 3 |
| TOMM20 | CDCA2 | 0.726907 | 3 | 0 | 3 |
| TOMM20 | WDR81 | 0.724009 | 4 | 0 | 4 |
| TOMM20 | DDX55 | 0.71865 | 4 | 0 | 4 |
| TOMM20 | PDRG1 | 0.716659 | 3 | 0 | 3 |
| TOMM20 | VMA21 | 0.716608 | 4 | 0 | 4 |
| TOMM20 | PRDM15 | 0.716071 | 3 | 0 | 3 |
| TOMM20 | TMEM138 | 0.715018 | 4 | 0 | 4 |
| TOMM20 | HSP90AB1 | 0.713838 | 6 | 0 | 6 |
| TOMM20 | CPT1A | 0.710433 | 3 | 0 | 3 |
| TOMM20 | ILF2 | 0.710303 | 9 | 0 | 8 |
| TOMM20 | METTL23 | 0.710175 | 5 | 0 | 5 |
| TOMM20 | QSOX2 | 0.70932 | 5 | 0 | 5 |
For details and further investigation, click here
