| Full name: La ribonucleoprotein domain family member 6 | Alias Symbol: acheron|FLJ11196 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 55323 | HGNC ID: HGNC:24012 | Ensembl Gene: ENSG00000166173 | OMIM ID: 611300 |
| Drug and gene relationship at DGIdb | |||
Expression of LARP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARP6 | 55323 | 236565_s_at | 1.5519 | 0.0493 | |
| GSE20347 | LARP6 | 55323 | 218651_s_at | 1.1454 | 0.0005 | |
| GSE23400 | LARP6 | 55323 | 218651_s_at | 0.0979 | 0.2826 | |
| GSE26886 | LARP6 | 55323 | 236565_s_at | 5.0243 | 0.0000 | |
| GSE29001 | LARP6 | 55323 | 218651_s_at | 0.5723 | 0.0537 | |
| GSE38129 | LARP6 | 55323 | 218651_s_at | 0.3891 | 0.3213 | |
| GSE45670 | LARP6 | 55323 | 236565_s_at | 1.2590 | 0.0098 | |
| GSE53622 | LARP6 | 55323 | 69960 | 1.4980 | 0.0000 | |
| GSE53624 | LARP6 | 55323 | 69960 | 2.2538 | 0.0000 | |
| GSE63941 | LARP6 | 55323 | 236565_s_at | -1.3860 | 0.0612 | |
| GSE77861 | LARP6 | 55323 | 236565_s_at | 1.6808 | 0.0027 | |
| GSE97050 | LARP6 | 55323 | A_33_P3237977 | 0.3238 | 0.2827 | |
| SRP007169 | LARP6 | 55323 | RNAseq | 4.8560 | 0.0000 | |
| SRP008496 | LARP6 | 55323 | RNAseq | 5.0162 | 0.0000 | |
| SRP064894 | LARP6 | 55323 | RNAseq | 1.2285 | 0.0005 | |
| SRP133303 | LARP6 | 55323 | RNAseq | 1.4612 | 0.0000 | |
| SRP159526 | LARP6 | 55323 | RNAseq | 2.5733 | 0.0000 | |
| SRP193095 | LARP6 | 55323 | RNAseq | 2.4985 | 0.0000 | |
| SRP219564 | LARP6 | 55323 | RNAseq | 1.2793 | 0.0306 | |
| TCGA | LARP6 | 55323 | RNAseq | -0.1960 | 0.0986 |
Upregulated datasets: 14; Downregulated datasets: 0.
Survival by LARP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LARP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARP6 | 55323 | 7 | 1 | 22 | |
| GSE20123 | LARP6 | 55323 | 7 | 1 | 22 | |
| GSE43470 | LARP6 | 55323 | 4 | 6 | 33 | |
| GSE46452 | LARP6 | 55323 | 3 | 7 | 49 | |
| GSE47630 | LARP6 | 55323 | 8 | 10 | 22 | |
| GSE54993 | LARP6 | 55323 | 5 | 6 | 59 | |
| GSE54994 | LARP6 | 55323 | 5 | 8 | 40 | |
| GSE60625 | LARP6 | 55323 | 4 | 4 | 3 | |
| GSE74703 | LARP6 | 55323 | 4 | 3 | 29 | |
| GSE74704 | LARP6 | 55323 | 3 | 1 | 16 | |
| TCGA | LARP6 | 55323 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 62; Total Number of normals: 366.
Somatic mutations of LARP6:
Generating mutation plots.
Highly correlated genes for LARP6:
Showing top 20/1882 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARP6 | CHIC1 | 0.822127 | 3 | 0 | 3 |
| LARP6 | RAB34 | 0.790889 | 3 | 0 | 3 |
| LARP6 | A4GALT | 0.775666 | 3 | 0 | 3 |
| LARP6 | SLC41A1 | 0.775087 | 7 | 0 | 7 |
| LARP6 | CD276 | 0.772617 | 5 | 0 | 5 |
| LARP6 | ZCCHC7 | 0.767088 | 3 | 0 | 3 |
| LARP6 | PYCR2 | 0.761759 | 3 | 0 | 3 |
| LARP6 | FMNL2 | 0.760961 | 7 | 0 | 7 |
| LARP6 | KIAA0100 | 0.755949 | 4 | 0 | 4 |
| LARP6 | KNSTRN | 0.75531 | 6 | 0 | 6 |
| LARP6 | AIMP2 | 0.754424 | 4 | 0 | 4 |
| LARP6 | ZCCHC3 | 0.751803 | 4 | 0 | 4 |
| LARP6 | SLC35B2 | 0.746692 | 3 | 0 | 3 |
| LARP6 | NF1 | 0.745112 | 3 | 0 | 3 |
| LARP6 | SHISA2 | 0.744964 | 6 | 0 | 6 |
| LARP6 | DNM1L | 0.741754 | 4 | 0 | 3 |
| LARP6 | CLN5 | 0.739602 | 3 | 0 | 3 |
| LARP6 | FCGR3A | 0.737217 | 3 | 0 | 3 |
| LARP6 | DDHD1 | 0.734911 | 8 | 0 | 8 |
| LARP6 | TP53I13 | 0.734518 | 7 | 0 | 6 |
For details and further investigation, click here
