| Full name: dynein cytoplasmic 2 light intermediate chain 1 | Alias Symbol: D2LIC|LIC3|CGI-60|DKFZP564A033 | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 51626 | HGNC ID: HGNC:24595 | Ensembl Gene: ENSG00000138036 | OMIM ID: 617083 |
| Drug and gene relationship at DGIdb | |||
Expression of DYNC2LI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNC2LI1 | 51626 | 203762_s_at | -0.0738 | 0.8757 | |
| GSE20347 | DYNC2LI1 | 51626 | 203763_at | 0.3101 | 0.0928 | |
| GSE23400 | DYNC2LI1 | 51626 | 203762_s_at | 0.0014 | 0.9660 | |
| GSE26886 | DYNC2LI1 | 51626 | 203763_at | 1.2447 | 0.0001 | |
| GSE29001 | DYNC2LI1 | 51626 | 203763_at | 0.2440 | 0.6449 | |
| GSE38129 | DYNC2LI1 | 51626 | 203762_s_at | 0.3431 | 0.0880 | |
| GSE45670 | DYNC2LI1 | 51626 | 203763_at | -0.2586 | 0.0803 | |
| GSE53622 | DYNC2LI1 | 51626 | 29253 | 0.1709 | 0.0457 | |
| GSE53624 | DYNC2LI1 | 51626 | 29253 | 0.1111 | 0.3476 | |
| GSE63941 | DYNC2LI1 | 51626 | 203762_s_at | -0.7207 | 0.1598 | |
| GSE77861 | DYNC2LI1 | 51626 | 203763_at | 0.3070 | 0.0150 | |
| GSE97050 | DYNC2LI1 | 51626 | A_23_P502170 | -0.1759 | 0.5191 | |
| SRP007169 | DYNC2LI1 | 51626 | RNAseq | 0.5105 | 0.2839 | |
| SRP008496 | DYNC2LI1 | 51626 | RNAseq | 0.4542 | 0.1165 | |
| SRP064894 | DYNC2LI1 | 51626 | RNAseq | 0.1118 | 0.3093 | |
| SRP133303 | DYNC2LI1 | 51626 | RNAseq | 0.2953 | 0.1362 | |
| SRP159526 | DYNC2LI1 | 51626 | RNAseq | 0.4384 | 0.0046 | |
| SRP193095 | DYNC2LI1 | 51626 | RNAseq | -0.1654 | 0.1662 | |
| SRP219564 | DYNC2LI1 | 51626 | RNAseq | 0.1529 | 0.5249 | |
| TCGA | DYNC2LI1 | 51626 | RNAseq | -0.0349 | 0.5722 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DYNC2LI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNC2LI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNC2LI1 | 51626 | 10 | 1 | 19 | |
| GSE20123 | DYNC2LI1 | 51626 | 9 | 1 | 20 | |
| GSE43470 | DYNC2LI1 | 51626 | 4 | 0 | 39 | |
| GSE46452 | DYNC2LI1 | 51626 | 1 | 4 | 54 | |
| GSE47630 | DYNC2LI1 | 51626 | 7 | 0 | 33 | |
| GSE54993 | DYNC2LI1 | 51626 | 0 | 5 | 65 | |
| GSE54994 | DYNC2LI1 | 51626 | 10 | 0 | 43 | |
| GSE60625 | DYNC2LI1 | 51626 | 0 | 3 | 8 | |
| GSE74703 | DYNC2LI1 | 51626 | 4 | 0 | 32 | |
| GSE74704 | DYNC2LI1 | 51626 | 9 | 1 | 10 | |
| TCGA | DYNC2LI1 | 51626 | 36 | 2 | 58 |
Total number of gains: 90; Total number of losses: 17; Total Number of normals: 381.
Somatic mutations of DYNC2LI1:
Generating mutation plots.
Highly correlated genes for DYNC2LI1:
Showing top 20/850 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNC2LI1 | TMTC1 | 0.785173 | 3 | 0 | 3 |
| DYNC2LI1 | MSI2 | 0.761499 | 3 | 0 | 3 |
| DYNC2LI1 | DDHD1 | 0.759586 | 3 | 0 | 3 |
| DYNC2LI1 | MTERF3 | 0.7586 | 3 | 0 | 3 |
| DYNC2LI1 | TSC22D1 | 0.755837 | 3 | 0 | 3 |
| DYNC2LI1 | DNM1L | 0.752835 | 4 | 0 | 4 |
| DYNC2LI1 | KCNE3 | 0.725882 | 3 | 0 | 3 |
| DYNC2LI1 | ZNF146 | 0.719726 | 4 | 0 | 4 |
| DYNC2LI1 | DHX40 | 0.714821 | 5 | 0 | 5 |
| DYNC2LI1 | THEM4 | 0.714482 | 3 | 0 | 3 |
| DYNC2LI1 | RDH14 | 0.709896 | 3 | 0 | 3 |
| DYNC2LI1 | PTPN4 | 0.70442 | 4 | 0 | 3 |
| DYNC2LI1 | SMCR8 | 0.703781 | 3 | 0 | 3 |
| DYNC2LI1 | ZCCHC3 | 0.702096 | 4 | 0 | 4 |
| DYNC2LI1 | DOCK11 | 0.698418 | 3 | 0 | 3 |
| DYNC2LI1 | C15orf61 | 0.697439 | 3 | 0 | 3 |
| DYNC2LI1 | SOX5 | 0.696159 | 3 | 0 | 3 |
| DYNC2LI1 | PET117 | 0.693739 | 3 | 0 | 3 |
| DYNC2LI1 | ZC3H12C | 0.688601 | 4 | 0 | 3 |
| DYNC2LI1 | TTC7B | 0.687798 | 3 | 0 | 3 |
For details and further investigation, click here
