| Full name: DNA damage inducible 1 homolog 1 | Alias Symbol: FLJ36017 | ||
| Type: protein-coding gene | Cytoband: 11q22.3 | ||
| Entrez ID: 414301 | HGNC ID: HGNC:18961 | Ensembl Gene: ENSG00000170967 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DDI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDI1 | 414301 | 239299_at | -0.2088 | 0.3212 | |
| GSE26886 | DDI1 | 414301 | 239299_at | -0.1913 | 0.0539 | |
| GSE45670 | DDI1 | 414301 | 239299_at | -0.0418 | 0.6212 | |
| GSE53622 | DDI1 | 414301 | 108557 | -0.0715 | 0.5130 | |
| GSE53624 | DDI1 | 414301 | 108557 | 0.4066 | 0.0000 | |
| GSE63941 | DDI1 | 414301 | 239299_at | -0.0392 | 0.8376 | |
| GSE77861 | DDI1 | 414301 | 239299_at | -0.1470 | 0.1435 | |
| TCGA | DDI1 | 414301 | RNAseq | -3.5702 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DDI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDI1 | 414301 | 2 | 10 | 18 | |
| GSE20123 | DDI1 | 414301 | 2 | 10 | 18 | |
| GSE43470 | DDI1 | 414301 | 3 | 5 | 35 | |
| GSE46452 | DDI1 | 414301 | 3 | 26 | 30 | |
| GSE47630 | DDI1 | 414301 | 2 | 19 | 19 | |
| GSE54993 | DDI1 | 414301 | 9 | 1 | 60 | |
| GSE54994 | DDI1 | 414301 | 4 | 19 | 30 | |
| GSE60625 | DDI1 | 414301 | 0 | 3 | 8 | |
| GSE74703 | DDI1 | 414301 | 2 | 3 | 31 | |
| GSE74704 | DDI1 | 414301 | 2 | 6 | 12 | |
| TCGA | DDI1 | 414301 | 8 | 45 | 43 |
Total number of gains: 37; Total number of losses: 147; Total Number of normals: 304.
Somatic mutations of DDI1:
Generating mutation plots.
Highly correlated genes for DDI1:
Showing top 20/60 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDI1 | AMACR | 0.66383 | 3 | 0 | 3 |
| DDI1 | TPRN | 0.648502 | 3 | 0 | 3 |
| DDI1 | SH3GL1 | 0.637572 | 4 | 0 | 4 |
| DDI1 | RALYL | 0.625043 | 3 | 0 | 3 |
| DDI1 | CES2 | 0.622031 | 3 | 0 | 3 |
| DDI1 | ZNF528 | 0.619288 | 4 | 0 | 3 |
| DDI1 | EML3 | 0.618846 | 4 | 0 | 3 |
| DDI1 | CYP4F12 | 0.606288 | 4 | 0 | 3 |
| DDI1 | GALR3 | 0.605876 | 3 | 0 | 3 |
| DDI1 | OAZ3 | 0.60403 | 3 | 0 | 3 |
| DDI1 | ST3GAL3 | 0.603344 | 4 | 0 | 3 |
| DDI1 | MIR210HG | 0.595677 | 3 | 0 | 3 |
| DDI1 | EPS8L2 | 0.594696 | 4 | 0 | 3 |
| DDI1 | USH1G | 0.591927 | 4 | 0 | 4 |
| DDI1 | RARG | 0.59178 | 4 | 0 | 4 |
| DDI1 | TRIP10 | 0.585964 | 4 | 0 | 3 |
| DDI1 | TPD52L1 | 0.584598 | 4 | 0 | 3 |
| DDI1 | PITRM1-AS1 | 0.582257 | 4 | 0 | 3 |
| DDI1 | DEFA5 | 0.579675 | 4 | 0 | 3 |
| DDI1 | PAK6 | 0.578701 | 4 | 0 | 3 |
For details and further investigation, click here
