| Full name: ornithine decarboxylase antizyme 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 51686 | HGNC ID: HGNC:8097 | Ensembl Gene: ENSG00000143450 | OMIM ID: 605138 |
| Drug and gene relationship at DGIdb | |||
Expression of OAZ3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OAZ3 | 51686 | 222075_s_at | -0.1318 | 0.8200 | |
| GSE20347 | OAZ3 | 51686 | 222075_s_at | -0.3885 | 0.0017 | |
| GSE23400 | OAZ3 | 51686 | 222075_s_at | -0.2249 | 0.0000 | |
| GSE26886 | OAZ3 | 51686 | 222075_s_at | -0.1606 | 0.3591 | |
| GSE29001 | OAZ3 | 51686 | 222075_s_at | -0.1461 | 0.4869 | |
| GSE38129 | OAZ3 | 51686 | 222075_s_at | -0.3085 | 0.0202 | |
| GSE45670 | OAZ3 | 51686 | 222075_s_at | -0.0432 | 0.8699 | |
| GSE53622 | OAZ3 | 51686 | 39341 | -0.2651 | 0.0006 | |
| GSE53624 | OAZ3 | 51686 | 39341 | -0.4798 | 0.0000 | |
| GSE63941 | OAZ3 | 51686 | 222075_s_at | -0.7256 | 0.1301 | |
| GSE77861 | OAZ3 | 51686 | 222075_s_at | -0.4174 | 0.0344 | |
| GSE97050 | OAZ3 | 51686 | A_32_P226078 | -0.1272 | 0.5931 | |
| SRP133303 | OAZ3 | 51686 | RNAseq | -0.1645 | 0.5517 | |
| SRP159526 | OAZ3 | 51686 | RNAseq | -0.2803 | 0.5937 | |
| SRP219564 | OAZ3 | 51686 | RNAseq | -0.3379 | 0.5616 | |
| TCGA | OAZ3 | 51686 | RNAseq | -0.0074 | 0.9743 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OAZ3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OAZ3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OAZ3 | 51686 | 15 | 0 | 15 | |
| GSE20123 | OAZ3 | 51686 | 15 | 0 | 15 | |
| GSE43470 | OAZ3 | 51686 | 8 | 2 | 33 | |
| GSE46452 | OAZ3 | 51686 | 2 | 1 | 56 | |
| GSE47630 | OAZ3 | 51686 | 15 | 0 | 25 | |
| GSE54993 | OAZ3 | 51686 | 0 | 4 | 66 | |
| GSE54994 | OAZ3 | 51686 | 15 | 0 | 38 | |
| GSE60625 | OAZ3 | 51686 | 0 | 0 | 11 | |
| GSE74703 | OAZ3 | 51686 | 7 | 1 | 28 | |
| GSE74704 | OAZ3 | 51686 | 7 | 0 | 13 | |
| TCGA | OAZ3 | 51686 | 38 | 2 | 56 |
Total number of gains: 122; Total number of losses: 10; Total Number of normals: 356.
Somatic mutations of OAZ3:
Generating mutation plots.
Highly correlated genes for OAZ3:
Showing top 20/157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OAZ3 | DEFA5 | 0.667854 | 3 | 0 | 3 |
| OAZ3 | EPB41 | 0.651588 | 3 | 0 | 3 |
| OAZ3 | FAM166A | 0.639769 | 3 | 0 | 3 |
| OAZ3 | SFT2D2 | 0.622876 | 5 | 0 | 5 |
| OAZ3 | MTA2 | 0.616422 | 4 | 0 | 4 |
| OAZ3 | GNG5 | 0.616064 | 6 | 0 | 5 |
| OAZ3 | SMPD2 | 0.609783 | 7 | 0 | 6 |
| OAZ3 | SPACA4 | 0.60941 | 3 | 0 | 3 |
| OAZ3 | MC5R | 0.606366 | 3 | 0 | 3 |
| OAZ3 | SERP2 | 0.604681 | 3 | 0 | 3 |
| OAZ3 | DDI1 | 0.60403 | 3 | 0 | 3 |
| OAZ3 | UCP1 | 0.599296 | 3 | 0 | 3 |
| OAZ3 | SEMA4A | 0.597771 | 5 | 0 | 3 |
| OAZ3 | NFE4 | 0.595296 | 3 | 0 | 3 |
| OAZ3 | SLC25A20 | 0.588328 | 6 | 0 | 4 |
| OAZ3 | ACAA1 | 0.582348 | 7 | 0 | 4 |
| OAZ3 | TOM1L2 | 0.582115 | 4 | 0 | 3 |
| OAZ3 | COMMD8 | 0.580458 | 4 | 0 | 4 |
| OAZ3 | TSSK2 | 0.579298 | 4 | 0 | 3 |
| OAZ3 | TSHB | 0.577271 | 4 | 0 | 4 |
For details and further investigation, click here
