| Full name: EMAP like 3 | Alias Symbol: FLJ35827|ELP95 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 256364 | HGNC ID: HGNC:26666 | Ensembl Gene: ENSG00000149499 | OMIM ID: 618118 |
| Drug and gene relationship at DGIdb | |||
Expression of EML3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EML3 | 256364 | 203442_x_at | -0.3931 | 0.4724 | |
| GSE20347 | EML3 | 256364 | 212969_x_at | -1.1623 | 0.0000 | |
| GSE23400 | EML3 | 256364 | 212969_x_at | -0.6006 | 0.0000 | |
| GSE26886 | EML3 | 256364 | 203442_x_at | -0.4395 | 0.0402 | |
| GSE29001 | EML3 | 256364 | 212969_x_at | -0.8788 | 0.0009 | |
| GSE38129 | EML3 | 256364 | 212969_x_at | -0.8685 | 0.0000 | |
| GSE45670 | EML3 | 256364 | 203442_x_at | -0.3848 | 0.0035 | |
| GSE53622 | EML3 | 256364 | 66901 | -0.3525 | 0.0000 | |
| GSE53624 | EML3 | 256364 | 66901 | -0.3711 | 0.0000 | |
| GSE63941 | EML3 | 256364 | 203442_x_at | 0.3379 | 0.3649 | |
| GSE77861 | EML3 | 256364 | 203442_x_at | -0.8142 | 0.0089 | |
| GSE97050 | EML3 | 256364 | A_23_P127793 | 0.3650 | 0.2569 | |
| SRP007169 | EML3 | 256364 | RNAseq | -2.3231 | 0.0000 | |
| SRP008496 | EML3 | 256364 | RNAseq | -1.9911 | 0.0000 | |
| SRP064894 | EML3 | 256364 | RNAseq | -0.5653 | 0.0002 | |
| SRP133303 | EML3 | 256364 | RNAseq | -1.0144 | 0.0000 | |
| SRP159526 | EML3 | 256364 | RNAseq | -0.9540 | 0.0000 | |
| SRP193095 | EML3 | 256364 | RNAseq | -0.4348 | 0.0030 | |
| SRP219564 | EML3 | 256364 | RNAseq | -0.4495 | 0.2110 | |
| TCGA | EML3 | 256364 | RNAseq | -0.0134 | 0.7936 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by EML3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EML3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EML3 | 256364 | 6 | 5 | 19 | |
| GSE20123 | EML3 | 256364 | 6 | 5 | 19 | |
| GSE43470 | EML3 | 256364 | 1 | 6 | 36 | |
| GSE46452 | EML3 | 256364 | 8 | 4 | 47 | |
| GSE47630 | EML3 | 256364 | 3 | 7 | 30 | |
| GSE54993 | EML3 | 256364 | 3 | 0 | 67 | |
| GSE54994 | EML3 | 256364 | 4 | 5 | 44 | |
| GSE60625 | EML3 | 256364 | 0 | 3 | 8 | |
| GSE74703 | EML3 | 256364 | 1 | 3 | 32 | |
| GSE74704 | EML3 | 256364 | 4 | 3 | 13 | |
| TCGA | EML3 | 256364 | 14 | 11 | 71 |
Total number of gains: 50; Total number of losses: 52; Total Number of normals: 386.
Somatic mutations of EML3:
Generating mutation plots.
Highly correlated genes for EML3:
Showing top 20/1148 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EML3 | ACAA1 | 0.758411 | 8 | 0 | 7 |
| EML3 | SLC35C1 | 0.757444 | 10 | 0 | 10 |
| EML3 | SFTA2 | 0.753546 | 4 | 0 | 4 |
| EML3 | CLIC3 | 0.753235 | 8 | 0 | 8 |
| EML3 | PPDPF | 0.752932 | 10 | 0 | 10 |
| EML3 | RHOF | 0.748731 | 3 | 0 | 3 |
| EML3 | SH3GL1 | 0.741679 | 12 | 0 | 11 |
| EML3 | FUT6 | 0.740799 | 10 | 0 | 10 |
| EML3 | CES2 | 0.738873 | 8 | 0 | 8 |
| EML3 | SCNN1B | 0.734747 | 10 | 0 | 9 |
| EML3 | PLEKHG6 | 0.732804 | 9 | 0 | 8 |
| EML3 | SULT2B1 | 0.73256 | 8 | 0 | 8 |
| EML3 | EPB41L4A | 0.730893 | 7 | 0 | 6 |
| EML3 | TRIP10 | 0.730766 | 11 | 0 | 10 |
| EML3 | USP6NL | 0.730455 | 8 | 0 | 8 |
| EML3 | ULK3 | 0.727827 | 6 | 0 | 6 |
| EML3 | PSCA | 0.727561 | 8 | 0 | 8 |
| EML3 | SPNS2 | 0.726524 | 4 | 0 | 4 |
| EML3 | PLEKHM1 | 0.720832 | 10 | 0 | 9 |
| EML3 | SLURP1 | 0.720729 | 10 | 0 | 9 |
For details and further investigation, click here
