| Full name: DEAD-box helicase 25 | Alias Symbol: GRTH | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 29118 | HGNC ID: HGNC:18698 | Ensembl Gene: ENSG00000109832 | OMIM ID: 607663 |
| Drug and gene relationship at DGIdb | |||
Expression of DDX25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX25 | 29118 | 219945_at | -0.1271 | 0.5492 | |
| GSE20347 | DDX25 | 29118 | 219945_at | -0.0098 | 0.9043 | |
| GSE23400 | DDX25 | 29118 | 219945_at | -0.0830 | 0.0014 | |
| GSE26886 | DDX25 | 29118 | 219945_at | 0.0874 | 0.4348 | |
| GSE29001 | DDX25 | 29118 | 219945_at | -0.0548 | 0.7539 | |
| GSE38129 | DDX25 | 29118 | 219945_at | -0.0650 | 0.2994 | |
| GSE45670 | DDX25 | 29118 | 219945_at | -0.1357 | 0.0978 | |
| GSE53622 | DDX25 | 29118 | 154927 | -0.4728 | 0.0012 | |
| GSE53624 | DDX25 | 29118 | 154927 | -0.7404 | 0.0000 | |
| GSE63941 | DDX25 | 29118 | 219945_at | 0.2414 | 0.0696 | |
| GSE77861 | DDX25 | 29118 | 219945_at | -0.0487 | 0.6892 | |
| SRP133303 | DDX25 | 29118 | RNAseq | -0.3819 | 0.0339 | |
| SRP193095 | DDX25 | 29118 | RNAseq | -0.3941 | 0.0292 | |
| TCGA | DDX25 | 29118 | RNAseq | -1.6193 | 0.2906 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX25 | 29118 | 0 | 13 | 17 | |
| GSE20123 | DDX25 | 29118 | 0 | 13 | 17 | |
| GSE43470 | DDX25 | 29118 | 2 | 7 | 34 | |
| GSE46452 | DDX25 | 29118 | 3 | 26 | 30 | |
| GSE47630 | DDX25 | 29118 | 2 | 19 | 19 | |
| GSE54993 | DDX25 | 29118 | 10 | 0 | 60 | |
| GSE54994 | DDX25 | 29118 | 5 | 19 | 29 | |
| GSE60625 | DDX25 | 29118 | 0 | 3 | 8 | |
| GSE74703 | DDX25 | 29118 | 1 | 5 | 30 | |
| GSE74704 | DDX25 | 29118 | 0 | 9 | 11 | |
| TCGA | DDX25 | 29118 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of DDX25:
Generating mutation plots.
Highly correlated genes for DDX25:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX25 | LINC00312 | 0.621805 | 3 | 0 | 3 |
| DDX25 | KHDRBS2 | 0.621089 | 5 | 0 | 5 |
| DDX25 | FOXG1 | 0.618665 | 3 | 0 | 3 |
| DDX25 | CLEC10A | 0.617468 | 4 | 0 | 3 |
| DDX25 | CCDC30 | 0.610921 | 4 | 0 | 3 |
| DDX25 | OR1C1 | 0.608736 | 3 | 0 | 3 |
| DDX25 | SPP2 | 0.601086 | 3 | 0 | 3 |
| DDX25 | KIR2DS2 | 0.596339 | 4 | 0 | 4 |
| DDX25 | TMEM145 | 0.595371 | 3 | 0 | 3 |
| DDX25 | ART4 | 0.591928 | 3 | 0 | 3 |
| DDX25 | LINGO3 | 0.590257 | 4 | 0 | 3 |
| DDX25 | MATN4 | 0.586521 | 4 | 0 | 3 |
| DDX25 | DSCR4 | 0.584481 | 5 | 0 | 4 |
| DDX25 | GNG13 | 0.583257 | 4 | 0 | 3 |
| DDX25 | LINC00334 | 0.580034 | 4 | 0 | 3 |
| DDX25 | KIR2DL2 | 0.572768 | 5 | 0 | 4 |
| DDX25 | ACVR2B-AS1 | 0.571306 | 4 | 0 | 3 |
| DDX25 | GPR12 | 0.569897 | 3 | 0 | 3 |
| DDX25 | TRH | 0.569107 | 6 | 0 | 5 |
| DDX25 | KIR2DL1 | 0.567922 | 3 | 0 | 3 |
For details and further investigation, click here
