| Full name: transmembrane protein 145 | Alias Symbol: FLJ90805 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 284339 | HGNC ID: HGNC:26912 | Ensembl Gene: ENSG00000167619 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM145:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM145 | 284339 | 1553479_at | 0.0599 | 0.8934 | |
| GSE26886 | TMEM145 | 284339 | 1553479_at | 0.3243 | 0.0132 | |
| GSE45670 | TMEM145 | 284339 | 1553479_at | 0.1597 | 0.1288 | |
| GSE53622 | TMEM145 | 284339 | 87586 | 0.2753 | 0.0000 | |
| GSE53624 | TMEM145 | 284339 | 87586 | 0.4345 | 0.0000 | |
| GSE63941 | TMEM145 | 284339 | 1553479_at | 0.3704 | 0.0460 | |
| GSE77861 | TMEM145 | 284339 | 1553479_at | 0.0002 | 0.9985 | |
| GSE97050 | TMEM145 | 284339 | A_33_P3257279 | 0.0501 | 0.8194 | |
| SRP159526 | TMEM145 | 284339 | RNAseq | 1.7313 | 0.0015 | |
| TCGA | TMEM145 | 284339 | RNAseq | -0.3183 | 0.5799 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM145 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM145:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM145 | 284339 | 4 | 5 | 21 | |
| GSE20123 | TMEM145 | 284339 | 4 | 4 | 22 | |
| GSE43470 | TMEM145 | 284339 | 4 | 11 | 28 | |
| GSE46452 | TMEM145 | 284339 | 47 | 1 | 11 | |
| GSE47630 | TMEM145 | 284339 | 8 | 6 | 26 | |
| GSE54993 | TMEM145 | 284339 | 17 | 4 | 49 | |
| GSE54994 | TMEM145 | 284339 | 7 | 12 | 34 | |
| GSE60625 | TMEM145 | 284339 | 9 | 0 | 2 | |
| GSE74703 | TMEM145 | 284339 | 4 | 7 | 25 | |
| GSE74704 | TMEM145 | 284339 | 4 | 2 | 14 | |
| TCGA | TMEM145 | 284339 | 13 | 16 | 67 |
Total number of gains: 121; Total number of losses: 68; Total Number of normals: 299.
Somatic mutations of TMEM145:
Generating mutation plots.
Highly correlated genes for TMEM145:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM145 | BSN | 0.758308 | 4 | 0 | 4 |
| TMEM145 | FTO | 0.735692 | 3 | 0 | 3 |
| TMEM145 | DNAH11 | 0.7301 | 3 | 0 | 3 |
| TMEM145 | TESK1 | 0.727874 | 3 | 0 | 3 |
| TMEM145 | RAB11B | 0.70287 | 3 | 0 | 3 |
| TMEM145 | AATK | 0.702344 | 4 | 0 | 4 |
| TMEM145 | CHST8 | 0.696819 | 3 | 0 | 3 |
| TMEM145 | TCP11L1 | 0.691896 | 3 | 0 | 3 |
| TMEM145 | MRPL45 | 0.685712 | 3 | 0 | 3 |
| TMEM145 | TP53I11 | 0.685437 | 3 | 0 | 3 |
| TMEM145 | CREB3 | 0.679886 | 3 | 0 | 3 |
| TMEM145 | PDAP1 | 0.679181 | 3 | 0 | 3 |
| TMEM145 | DENND5B | 0.678031 | 3 | 0 | 3 |
| TMEM145 | OCEL1 | 0.67746 | 3 | 0 | 3 |
| TMEM145 | ZNF414 | 0.675905 | 4 | 0 | 4 |
| TMEM145 | ZNF837 | 0.673297 | 3 | 0 | 3 |
| TMEM145 | GSK3A | 0.67122 | 4 | 0 | 4 |
| TMEM145 | KLHL31 | 0.66567 | 3 | 0 | 3 |
| TMEM145 | VWA1 | 0.662076 | 3 | 0 | 3 |
| TMEM145 | CNIH2 | 0.660387 | 3 | 0 | 3 |
For details and further investigation, click here
