| Full name: importin 9 | Alias Symbol: Imp9|FLJ10402 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 55705 | HGNC ID: HGNC:19425 | Ensembl Gene: ENSG00000198700 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IPO9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IPO9 | 55705 | 217885_at | 0.9860 | 0.0269 | |
| GSE20347 | IPO9 | 55705 | 217885_at | 1.0346 | 0.0000 | |
| GSE23400 | IPO9 | 55705 | 217885_at | 0.7438 | 0.0000 | |
| GSE26886 | IPO9 | 55705 | 217885_at | 1.2099 | 0.0000 | |
| GSE29001 | IPO9 | 55705 | 217885_at | 1.0317 | 0.0001 | |
| GSE38129 | IPO9 | 55705 | 217885_at | 0.9429 | 0.0000 | |
| GSE45670 | IPO9 | 55705 | 217885_at | 0.6769 | 0.0000 | |
| GSE53622 | IPO9 | 55705 | 42352 | -0.3651 | 0.0283 | |
| GSE53624 | IPO9 | 55705 | 42352 | 0.0922 | 0.5725 | |
| GSE63941 | IPO9 | 55705 | 217885_at | 1.5185 | 0.0001 | |
| GSE77861 | IPO9 | 55705 | 217885_at | 1.0238 | 0.0003 | |
| SRP007169 | IPO9 | 55705 | RNAseq | 1.2237 | 0.0001 | |
| SRP008496 | IPO9 | 55705 | RNAseq | 1.0646 | 0.0000 | |
| SRP064894 | IPO9 | 55705 | RNAseq | 0.7650 | 0.0000 | |
| SRP133303 | IPO9 | 55705 | RNAseq | 0.6848 | 0.0000 | |
| SRP159526 | IPO9 | 55705 | RNAseq | 1.0271 | 0.0000 | |
| SRP193095 | IPO9 | 55705 | RNAseq | 0.7864 | 0.0000 | |
| SRP219564 | IPO9 | 55705 | RNAseq | 0.6155 | 0.0418 | |
| TCGA | IPO9 | 55705 | RNAseq | 0.1585 | 0.0004 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by IPO9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IPO9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IPO9 | 55705 | 11 | 0 | 19 | |
| GSE20123 | IPO9 | 55705 | 11 | 0 | 19 | |
| GSE43470 | IPO9 | 55705 | 6 | 0 | 37 | |
| GSE46452 | IPO9 | 55705 | 3 | 1 | 55 | |
| GSE47630 | IPO9 | 55705 | 14 | 0 | 26 | |
| GSE54993 | IPO9 | 55705 | 0 | 6 | 64 | |
| GSE54994 | IPO9 | 55705 | 15 | 0 | 38 | |
| GSE60625 | IPO9 | 55705 | 0 | 0 | 11 | |
| GSE74703 | IPO9 | 55705 | 6 | 0 | 30 | |
| GSE74704 | IPO9 | 55705 | 5 | 0 | 15 | |
| TCGA | IPO9 | 55705 | 44 | 5 | 47 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of IPO9:
Generating mutation plots.
Highly correlated genes for IPO9:
Showing top 20/1580 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IPO9 | PLXNA1 | 0.822717 | 8 | 0 | 8 |
| IPO9 | MSTO1 | 0.815026 | 4 | 0 | 4 |
| IPO9 | FBRSL1 | 0.810307 | 4 | 0 | 4 |
| IPO9 | NSL1 | 0.797266 | 7 | 0 | 7 |
| IPO9 | CENPF | 0.797223 | 9 | 0 | 9 |
| IPO9 | HNRNPU | 0.796036 | 7 | 0 | 7 |
| IPO9 | SLC39A3 | 0.78931 | 3 | 0 | 3 |
| IPO9 | TEAD2 | 0.787843 | 3 | 0 | 3 |
| IPO9 | DENND4B | 0.785925 | 8 | 0 | 8 |
| IPO9 | LPCAT1 | 0.776037 | 8 | 0 | 8 |
| IPO9 | FUCA2 | 0.773876 | 3 | 0 | 3 |
| IPO9 | DHX9 | 0.769099 | 9 | 0 | 9 |
| IPO9 | TCF3 | 0.768395 | 9 | 0 | 9 |
| IPO9 | SAC3D1 | 0.768113 | 8 | 0 | 8 |
| IPO9 | U2SURP | 0.762846 | 9 | 0 | 9 |
| IPO9 | BRAT1 | 0.762022 | 4 | 0 | 4 |
| IPO9 | TMEM138 | 0.761554 | 4 | 0 | 4 |
| IPO9 | ANP32E | 0.761285 | 9 | 0 | 9 |
| IPO9 | TMEM9 | 0.759523 | 5 | 0 | 5 |
| IPO9 | RBM12B | 0.75887 | 5 | 0 | 5 |
For details and further investigation, click here
