| Full name: DiGeorge syndrome critical region gene 5 | Alias Symbol: NCRNA00037|LINC00037 | ||
| Type: non-coding RNA | Cytoband: 22q11.21 | ||
| Entrez ID: 26220 | HGNC ID: HGNC:16757 | Ensembl Gene: ENSG00000237517 | OMIM ID: 618040 |
| Drug and gene relationship at DGIdb | |||
Expression of DGCR5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGCR5 | 26220 | 228804_at | 0.3516 | 0.3119 | |
| GSE20347 | DGCR5 | 26220 | 215244_at | -0.0271 | 0.7380 | |
| GSE23400 | DGCR5 | 26220 | 215244_at | -0.1776 | 0.0000 | |
| GSE26886 | DGCR5 | 26220 | 228804_at | 0.4076 | 0.0035 | |
| GSE29001 | DGCR5 | 26220 | 215244_at | -0.1035 | 0.4677 | |
| GSE38129 | DGCR5 | 26220 | 215244_at | -0.0936 | 0.4319 | |
| GSE45670 | DGCR5 | 26220 | 228804_at | 0.0186 | 0.8948 | |
| GSE53622 | DGCR5 | 26220 | 23173 | 1.1939 | 0.0000 | |
| GSE53624 | DGCR5 | 26220 | 23173 | 0.6978 | 0.0000 | |
| GSE63941 | DGCR5 | 26220 | 228804_at | 0.2095 | 0.3546 | |
| GSE77861 | DGCR5 | 26220 | 228804_at | 0.0350 | 0.8627 | |
| SRP133303 | DGCR5 | 26220 | RNAseq | 0.6656 | 0.0395 | |
| SRP159526 | DGCR5 | 26220 | RNAseq | 2.7592 | 0.0004 | |
| SRP219564 | DGCR5 | 26220 | RNAseq | 2.1232 | 0.0080 | |
| TCGA | DGCR5 | 26220 | RNAseq | 1.7872 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by DGCR5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGCR5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGCR5 | 26220 | 4 | 8 | 18 | |
| GSE20123 | DGCR5 | 26220 | 4 | 8 | 18 | |
| GSE43470 | DGCR5 | 26220 | 5 | 7 | 31 | |
| GSE46452 | DGCR5 | 26220 | 32 | 2 | 25 | |
| GSE47630 | DGCR5 | 26220 | 8 | 5 | 27 | |
| GSE54993 | DGCR5 | 26220 | 3 | 6 | 61 | |
| GSE54994 | DGCR5 | 26220 | 12 | 7 | 34 | |
| GSE60625 | DGCR5 | 26220 | 5 | 0 | 6 | |
| GSE74703 | DGCR5 | 26220 | 5 | 5 | 26 | |
| GSE74704 | DGCR5 | 26220 | 2 | 5 | 13 | |
| TCGA | DGCR5 | 26220 | 27 | 17 | 52 |
Total number of gains: 107; Total number of losses: 70; Total Number of normals: 311.
Somatic mutations of DGCR5:
Generating mutation plots.
Highly correlated genes for DGCR5:
Showing top 20/657 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGCR5 | OXT | 0.729377 | 4 | 0 | 4 |
| DGCR5 | DGKD | 0.718273 | 3 | 0 | 3 |
| DGCR5 | AMACR | 0.706553 | 3 | 0 | 3 |
| DGCR5 | SSTR4 | 0.703106 | 4 | 0 | 4 |
| DGCR5 | SPTBN5 | 0.695701 | 3 | 0 | 3 |
| DGCR5 | CHD2 | 0.687152 | 3 | 0 | 3 |
| DGCR5 | GIT1 | 0.684545 | 4 | 0 | 4 |
| DGCR5 | SAMD4B | 0.682607 | 5 | 0 | 5 |
| DGCR5 | FSCN3 | 0.681686 | 5 | 0 | 4 |
| DGCR5 | G6PC2 | 0.67976 | 4 | 0 | 3 |
| DGCR5 | RGSL1 | 0.678608 | 4 | 0 | 4 |
| DGCR5 | ADAM30 | 0.677557 | 5 | 0 | 4 |
| DGCR5 | ELFN1 | 0.675967 | 3 | 0 | 3 |
| DGCR5 | RFPL2 | 0.669864 | 3 | 0 | 3 |
| DGCR5 | FOXD3-AS1 | 0.667635 | 3 | 0 | 3 |
| DGCR5 | DPP7 | 0.662864 | 3 | 0 | 3 |
| DGCR5 | BEST1 | 0.661353 | 4 | 0 | 3 |
| DGCR5 | CAMKV | 0.660709 | 5 | 0 | 5 |
| DGCR5 | OR10H3 | 0.65869 | 4 | 0 | 3 |
| DGCR5 | PHLDB1 | 0.657673 | 4 | 0 | 4 |
For details and further investigation, click here
