TRMT1

 

Full name: tRNA methyltransferase 1 Alias Symbol: FLJ20244|TRM1
Type: protein-coding gene Cytoband: 19p13.13
Entrez ID: 55621 HGNC ID: HGNC:25980 Ensembl Gene: ENSG00000104907 OMIM ID: 611669
Drug and gene relationship at DGIdb

 

Expression of TRMT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRMT1 55621 210463_x_at 0.6617 0.2830
GSE20347 TRMT1 55621 210463_x_at 0.5389 0.0006
GSE23400 TRMT1 55621 210463_x_at 0.5435 0.0000
GSE26886 TRMT1 55621 203701_s_at 0.2213 0.2331
GSE29001 TRMT1 55621 210463_x_at 0.7921 0.0507
GSE38129 TRMT1 55621 203701_s_at 0.4748 0.0002
GSE45670 TRMT1 55621 203701_s_at 0.4331 0.0067
GSE53622 TRMT1 55621 121711 0.4879 0.0000
GSE53624 TRMT1 55621 121711 0.6609 0.0000
GSE63941 TRMT1 55621 210463_x_at 0.9325 0.0659
GSE77861 TRMT1 55621 203701_s_at 0.6180 0.0081
GSE97050 TRMT1 55621 A_23_P16683 0.4807 0.2396
SRP007169 TRMT1 55621 RNAseq 1.2042 0.0591
SRP064894 TRMT1 55621 RNAseq 0.9262 0.0004
SRP133303 TRMT1 55621 RNAseq 0.2406 0.1714
SRP159526 TRMT1 55621 RNAseq 0.3833 0.3156
SRP193095 TRMT1 55621 RNAseq 0.5807 0.0000
SRP219564 TRMT1 55621 RNAseq 1.2936 0.0273
TCGA TRMT1 55621 RNAseq 0.2961 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TRMT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TRMT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRMT1 55621 4 2 24
GSE20123 TRMT1 55621 3 1 26
GSE43470 TRMT1 55621 2 6 35
GSE46452 TRMT1 55621 47 1 11
GSE47630 TRMT1 55621 4 7 29
GSE54993 TRMT1 55621 16 3 51
GSE54994 TRMT1 55621 6 13 34
GSE60625 TRMT1 55621 9 0 2
GSE74703 TRMT1 55621 2 4 30
GSE74704 TRMT1 55621 0 1 19
TCGA TRMT1 55621 18 13 65

Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.  

 

Somatic mutations of TRMT1:

 

Generating mutation plots.

 

Highly correlated genes for TRMT1:

 

Showing top 20/1311 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRMT1SLC39A30.760863303
TRMT1SCNM10.740223303
TRMT1DNMT10.73760210010
TRMT1ILF30.73423312012
TRMT1CEP410.732999303
TRMT1ELOF10.726278605
TRMT1LILRB20.724609303
TRMT1CRTC20.72348504
TRMT1TMEM63B0.720304403
TRMT1PHC20.711046404
TRMT1CHERP0.7078681109
TRMT1G2E30.703855505
TRMT1EBNA1BP20.702824303
TRMT1KRI10.70270612011
TRMT1DDX39A0.70232512010
TRMT1UBE2C0.70182410010
TRMT1TYK20.69929611011
TRMT1NOP20.69924112011
TRMT1GPR1070.698815303
TRMT1CDCA20.698065404

For details and further investigation, click here