| Full name: heterogeneous nuclear ribonucleoprotein L | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 3191 | HGNC ID: HGNC:5045 | Ensembl Gene: ENSG00000104824 | OMIM ID: 603083 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HNRNPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HNRNPL | 3191 | 35201_at | 0.3849 | 0.5964 | |
| GSE20347 | HNRNPL | 3191 | 35201_at | 0.1477 | 0.1441 | |
| GSE23400 | HNRNPL | 3191 | 35201_at | 0.2025 | 0.0000 | |
| GSE26886 | HNRNPL | 3191 | 35201_at | -0.1455 | 0.5179 | |
| GSE29001 | HNRNPL | 3191 | 35201_at | -0.0024 | 0.9895 | |
| GSE38129 | HNRNPL | 3191 | 35201_at | 0.2258 | 0.1776 | |
| GSE45670 | HNRNPL | 3191 | 35201_at | 0.2924 | 0.0350 | |
| GSE63941 | HNRNPL | 3191 | 35201_at | -0.4630 | 0.2316 | |
| GSE77861 | HNRNPL | 3191 | 35201_at | 0.1689 | 0.3255 | |
| GSE97050 | HNRNPL | 3191 | A_32_P109572 | 0.2401 | 0.2858 | |
| SRP007169 | HNRNPL | 3191 | RNAseq | 0.5701 | 0.0965 | |
| SRP008496 | HNRNPL | 3191 | RNAseq | 0.3318 | 0.1294 | |
| SRP064894 | HNRNPL | 3191 | RNAseq | 0.3554 | 0.0136 | |
| SRP133303 | HNRNPL | 3191 | RNAseq | 0.2739 | 0.0356 | |
| SRP159526 | HNRNPL | 3191 | RNAseq | 0.2949 | 0.1231 | |
| SRP193095 | HNRNPL | 3191 | RNAseq | 0.1341 | 0.0555 | |
| SRP219564 | HNRNPL | 3191 | RNAseq | 0.2726 | 0.1360 | |
| TCGA | HNRNPL | 3191 | RNAseq | 0.1487 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HNRNPL expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPL | 3191 | 7 | 4 | 19 | |
| GSE20123 | HNRNPL | 3191 | 7 | 3 | 20 | |
| GSE43470 | HNRNPL | 3191 | 4 | 10 | 29 | |
| GSE46452 | HNRNPL | 3191 | 47 | 2 | 10 | |
| GSE47630 | HNRNPL | 3191 | 9 | 5 | 26 | |
| GSE54993 | HNRNPL | 3191 | 17 | 3 | 50 | |
| GSE54994 | HNRNPL | 3191 | 6 | 9 | 38 | |
| GSE60625 | HNRNPL | 3191 | 9 | 0 | 2 | |
| GSE74703 | HNRNPL | 3191 | 4 | 6 | 26 | |
| GSE74704 | HNRNPL | 3191 | 7 | 1 | 12 | |
| TCGA | HNRNPL | 3191 | 15 | 15 | 66 |
Total number of gains: 132; Total number of losses: 58; Total Number of normals: 298.
Somatic mutations of HNRNPL:
Generating mutation plots.
Highly correlated genes for HNRNPL:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPL | ARHGAP17 | 0.744899 | 3 | 0 | 3 |
| HNRNPL | IGSF6 | 0.73423 | 3 | 0 | 3 |
| HNRNPL | ZNF609 | 0.727284 | 3 | 0 | 3 |
| HNRNPL | SP3 | 0.718598 | 3 | 0 | 3 |
| HNRNPL | MGAT5 | 0.71589 | 3 | 0 | 3 |
| HNRNPL | AP3D1 | 0.710825 | 3 | 0 | 3 |
| HNRNPL | GATAD2A | 0.710533 | 3 | 0 | 3 |
| HNRNPL | PNKP | 0.700325 | 3 | 0 | 3 |
| HNRNPL | DGKQ | 0.696436 | 3 | 0 | 3 |
| HNRNPL | PRR14L | 0.695251 | 4 | 0 | 3 |
| HNRNPL | HERC4 | 0.69168 | 3 | 0 | 3 |
| HNRNPL | ARL13B | 0.690043 | 3 | 0 | 3 |
| HNRNPL | CDK9 | 0.689318 | 5 | 0 | 3 |
| HNRNPL | LDLR | 0.682796 | 3 | 0 | 3 |
| HNRNPL | NLK | 0.673916 | 4 | 0 | 3 |
| HNRNPL | YWHAH | 0.670326 | 4 | 0 | 4 |
| HNRNPL | PHF5A | 0.669573 | 4 | 0 | 3 |
| HNRNPL | NOSIP | 0.668089 | 5 | 0 | 4 |
| HNRNPL | GMPR2 | 0.667433 | 3 | 0 | 3 |
| HNRNPL | ACIN1 | 0.654475 | 5 | 0 | 3 |
For details and further investigation, click here
