ADRM1

 

Full name: adhesion regulating molecule 1 Alias Symbol: GP110|Rpn13|ARM1
Type: protein-coding gene Cytoband: 20q13.33
Entrez ID: 11047 HGNC ID: HGNC:15759 Ensembl Gene: ENSG00000130706 OMIM ID: 610650
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ADRM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ADRM1 11047 201281_at 0.8071 0.0106
GSE20347 ADRM1 11047 201281_at 0.4340 0.0004
GSE23400 ADRM1 11047 201281_at 0.4732 0.0000
GSE26886 ADRM1 11047 201281_at 0.9911 0.0001
GSE29001 ADRM1 11047 201281_at 0.3720 0.0969
GSE38129 ADRM1 11047 201281_at 0.5300 0.0000
GSE45670 ADRM1 11047 201281_at 0.5583 0.0002
GSE53622 ADRM1 11047 86811 0.4936 0.0000
GSE53624 ADRM1 11047 86811 0.5782 0.0000
GSE63941 ADRM1 11047 201281_at 0.9610 0.0122
GSE77861 ADRM1 11047 201281_at 0.5821 0.0084
GSE97050 ADRM1 11047 A_23_P68665 0.7817 0.1310
SRP007169 ADRM1 11047 RNAseq -0.4822 0.1347
SRP008496 ADRM1 11047 RNAseq -0.3057 0.1043
SRP064894 ADRM1 11047 RNAseq 0.5835 0.0114
SRP133303 ADRM1 11047 RNAseq 0.5490 0.0000
SRP159526 ADRM1 11047 RNAseq 0.4421 0.0223
SRP193095 ADRM1 11047 RNAseq 0.5504 0.0000
SRP219564 ADRM1 11047 RNAseq 0.3936 0.2241
TCGA ADRM1 11047 RNAseq 0.2474 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ADRM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ADRM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ADRM1 11047 13 2 15
GSE20123 ADRM1 11047 14 2 14
GSE43470 ADRM1 11047 11 1 31
GSE46452 ADRM1 11047 35 0 24
GSE47630 ADRM1 11047 25 1 14
GSE54993 ADRM1 11047 0 17 53
GSE54994 ADRM1 11047 29 0 24
GSE60625 ADRM1 11047 0 0 11
GSE74703 ADRM1 11047 10 0 26
GSE74704 ADRM1 11047 11 0 9
TCGA ADRM1 11047 43 4 49

Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.  

 

Somatic mutations of ADRM1:

 

Generating mutation plots.

 

Highly correlated genes for ADRM1:

 

Showing top 20/2123 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ADRM1SMAD10.821543303
ADRM1SOCS70.774308303
ADRM1EBNA1BP20.773794303
ADRM1KTI120.770494303
ADRM1C8orf760.767929404
ADRM1PACS10.765433404
ADRM1NACC10.764031505
ADRM1TRADD0.762845303
ADRM1SSBP40.762838404
ADRM1PSMG30.762482707
ADRM1DHX370.760175606
ADRM1IRF2BPL0.754501303
ADRM1RAVER10.753437505
ADRM1MRGBP0.75190911010
ADRM1BRMS10.74552410010
ADRM1DNMT3A0.743869303
ADRM1ZNF4960.737262404
ADRM1WDR40.736488505
ADRM1CDCA20.736224505
ADRM1GTPBP100.735989303

For details and further investigation, click here