| Full name: TruB pseudouridine synthase family member 2 | Alias Symbol: CLONE24922 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 26995 | HGNC ID: HGNC:17170 | Ensembl Gene: ENSG00000167112 | OMIM ID: 610727 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRUB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRUB2 | 26995 | 223109_at | 0.4149 | 0.3033 | |
| GSE26886 | TRUB2 | 26995 | 223109_at | 0.1254 | 0.4509 | |
| GSE45670 | TRUB2 | 26995 | 223109_at | 0.3451 | 0.0039 | |
| GSE53622 | TRUB2 | 26995 | 37370 | 0.2965 | 0.0000 | |
| GSE53624 | TRUB2 | 26995 | 37370 | 0.3621 | 0.0000 | |
| GSE63941 | TRUB2 | 26995 | 223109_at | 0.5731 | 0.0473 | |
| GSE77861 | TRUB2 | 26995 | 223109_at | 0.3630 | 0.0342 | |
| GSE97050 | TRUB2 | 26995 | A_23_P169428 | 0.3644 | 0.2839 | |
| SRP007169 | TRUB2 | 26995 | RNAseq | 0.4928 | 0.2606 | |
| SRP008496 | TRUB2 | 26995 | RNAseq | 0.3901 | 0.1476 | |
| SRP064894 | TRUB2 | 26995 | RNAseq | 0.6695 | 0.0095 | |
| SRP133303 | TRUB2 | 26995 | RNAseq | 0.1941 | 0.2785 | |
| SRP159526 | TRUB2 | 26995 | RNAseq | 0.6239 | 0.0010 | |
| SRP193095 | TRUB2 | 26995 | RNAseq | 0.1292 | 0.2146 | |
| SRP219564 | TRUB2 | 26995 | RNAseq | 0.2522 | 0.4851 | |
| TCGA | TRUB2 | 26995 | RNAseq | 0.0976 | 0.0870 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRUB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRUB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRUB2 | 26995 | 6 | 9 | 15 | |
| GSE20123 | TRUB2 | 26995 | 6 | 9 | 15 | |
| GSE43470 | TRUB2 | 26995 | 5 | 7 | 31 | |
| GSE46452 | TRUB2 | 26995 | 6 | 13 | 40 | |
| GSE47630 | TRUB2 | 26995 | 3 | 16 | 21 | |
| GSE54993 | TRUB2 | 26995 | 3 | 3 | 64 | |
| GSE54994 | TRUB2 | 26995 | 11 | 8 | 34 | |
| GSE60625 | TRUB2 | 26995 | 0 | 0 | 11 | |
| GSE74703 | TRUB2 | 26995 | 5 | 5 | 26 | |
| GSE74704 | TRUB2 | 26995 | 3 | 7 | 10 | |
| TCGA | TRUB2 | 26995 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 101; Total Number of normals: 312.
Somatic mutations of TRUB2:
Generating mutation plots.
Highly correlated genes for TRUB2:
Showing top 20/889 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRUB2 | PEX13 | 0.787576 | 3 | 0 | 3 |
| TRUB2 | SMAD1 | 0.764292 | 3 | 0 | 3 |
| TRUB2 | NIPBL | 0.762862 | 3 | 0 | 3 |
| TRUB2 | ADAM15 | 0.75123 | 3 | 0 | 3 |
| TRUB2 | THADA | 0.744869 | 3 | 0 | 3 |
| TRUB2 | DVL1 | 0.74363 | 3 | 0 | 3 |
| TRUB2 | MED26 | 0.740023 | 4 | 0 | 4 |
| TRUB2 | CRCP | 0.734374 | 3 | 0 | 3 |
| TRUB2 | AP3D1 | 0.727604 | 3 | 0 | 3 |
| TRUB2 | PLEKHM2 | 0.726356 | 3 | 0 | 3 |
| TRUB2 | TMEM223 | 0.726167 | 4 | 0 | 4 |
| TRUB2 | BCL2L1 | 0.724774 | 3 | 0 | 3 |
| TRUB2 | MRPS28 | 0.72166 | 3 | 0 | 3 |
| TRUB2 | CHD4 | 0.718026 | 3 | 0 | 3 |
| TRUB2 | ANAPC7 | 0.709559 | 3 | 0 | 3 |
| TRUB2 | TRPM4 | 0.708423 | 3 | 0 | 3 |
| TRUB2 | LCMT1 | 0.706208 | 3 | 0 | 3 |
| TRUB2 | SNRNP35 | 0.703879 | 3 | 0 | 3 |
| TRUB2 | DKC1 | 0.700442 | 3 | 0 | 3 |
| TRUB2 | BTF3L4 | 0.696383 | 3 | 0 | 3 |
For details and further investigation, click here
