| Full name: discs large MAGUK scaffold protein 3 | Alias Symbol: NE-Dlg|SAP102|SAP-102|NEDLG|KIAA1232|MRX90|PPP1R82 | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 1741 | HGNC ID: HGNC:2902 | Ensembl Gene: ENSG00000082458 | OMIM ID: 300189 |
| Drug and gene relationship at DGIdb | |||
DLG3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04390 | Hippo signaling pathway |
Expression of DLG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLG3 | 1741 | 212727_at | -0.3195 | 0.5096 | |
| GSE20347 | DLG3 | 1741 | 212727_at | -0.3020 | 0.0155 | |
| GSE23400 | DLG3 | 1741 | 212727_at | -0.2606 | 0.0000 | |
| GSE26886 | DLG3 | 1741 | 212727_at | -0.7615 | 0.0181 | |
| GSE29001 | DLG3 | 1741 | 212727_at | -0.4228 | 0.1933 | |
| GSE38129 | DLG3 | 1741 | 212727_at | -0.3012 | 0.0056 | |
| GSE45670 | DLG3 | 1741 | 212727_at | -0.4318 | 0.0104 | |
| GSE53622 | DLG3 | 1741 | 60589 | -1.0813 | 0.0000 | |
| GSE53624 | DLG3 | 1741 | 60589 | -0.8402 | 0.0000 | |
| GSE63941 | DLG3 | 1741 | 212727_at | 0.6143 | 0.2965 | |
| GSE77861 | DLG3 | 1741 | 212727_at | -0.0116 | 0.9441 | |
| GSE97050 | DLG3 | 1741 | A_24_P945283 | -0.9608 | 0.1076 | |
| SRP007169 | DLG3 | 1741 | RNAseq | -1.4673 | 0.0031 | |
| SRP008496 | DLG3 | 1741 | RNAseq | -1.4922 | 0.0000 | |
| SRP064894 | DLG3 | 1741 | RNAseq | -0.8123 | 0.0000 | |
| SRP133303 | DLG3 | 1741 | RNAseq | -0.7327 | 0.0053 | |
| SRP159526 | DLG3 | 1741 | RNAseq | -0.7891 | 0.0002 | |
| SRP193095 | DLG3 | 1741 | RNAseq | -0.9043 | 0.0000 | |
| SRP219564 | DLG3 | 1741 | RNAseq | -0.7982 | 0.0032 | |
| TCGA | DLG3 | 1741 | RNAseq | -0.2855 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by DLG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLG3:
No record found for this gene.
Somatic mutations of DLG3:
Generating mutation plots.
Highly correlated genes for DLG3:
Showing top 20/714 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLG3 | FIS1 | 0.804971 | 3 | 0 | 3 |
| DLG3 | PRKAG1 | 0.797082 | 3 | 0 | 3 |
| DLG3 | C5orf51 | 0.762775 | 3 | 0 | 3 |
| DLG3 | SMAD3 | 0.753192 | 3 | 0 | 3 |
| DLG3 | ING4 | 0.753011 | 3 | 0 | 3 |
| DLG3 | MRPS33 | 0.745385 | 3 | 0 | 3 |
| DLG3 | GLCE | 0.737893 | 4 | 0 | 4 |
| DLG3 | RASSF9 | 0.728346 | 3 | 0 | 3 |
| DLG3 | GOLPH3 | 0.727917 | 3 | 0 | 3 |
| DLG3 | CHCHD1 | 0.727797 | 3 | 0 | 3 |
| DLG3 | COPZ1 | 0.719969 | 4 | 0 | 4 |
| DLG3 | CCDC25 | 0.718015 | 3 | 0 | 3 |
| DLG3 | BBIP1 | 0.713009 | 3 | 0 | 3 |
| DLG3 | ADAM11 | 0.711198 | 3 | 0 | 3 |
| DLG3 | SCARB2 | 0.707682 | 3 | 0 | 3 |
| DLG3 | PPM1L | 0.702399 | 6 | 0 | 6 |
| DLG3 | USP24 | 0.699677 | 3 | 0 | 3 |
| DLG3 | ASB9 | 0.697745 | 3 | 0 | 3 |
| DLG3 | GDPD1 | 0.696979 | 4 | 0 | 3 |
| DLG3 | XPO7 | 0.696878 | 3 | 0 | 3 |
For details and further investigation, click here
