| Full name: PDZ and LIM domain 1 | Alias Symbol: CLP-36|hCLIM1|CLP36 | ||
| Type: protein-coding gene | Cytoband: 10q23.33 | ||
| Entrez ID: 9124 | HGNC ID: HGNC:2067 | Ensembl Gene: ENSG00000107438 | OMIM ID: 605900 |
| Drug and gene relationship at DGIdb | |||
Expression of PDLIM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDLIM1 | 9124 | 208690_s_at | -0.2212 | 0.7823 | |
| GSE20347 | PDLIM1 | 9124 | 208690_s_at | -0.1963 | 0.4203 | |
| GSE23400 | PDLIM1 | 9124 | 208690_s_at | 0.1633 | 0.1014 | |
| GSE26886 | PDLIM1 | 9124 | 208690_s_at | 0.1506 | 0.4662 | |
| GSE29001 | PDLIM1 | 9124 | 208690_s_at | -0.1444 | 0.5885 | |
| GSE38129 | PDLIM1 | 9124 | 208690_s_at | 0.0667 | 0.7608 | |
| GSE45670 | PDLIM1 | 9124 | 208690_s_at | 0.3126 | 0.0991 | |
| GSE53622 | PDLIM1 | 9124 | 14939 | 0.0992 | 0.4812 | |
| GSE53624 | PDLIM1 | 9124 | 14939 | 0.0772 | 0.3457 | |
| GSE63941 | PDLIM1 | 9124 | 208690_s_at | 0.4329 | 0.5109 | |
| GSE77861 | PDLIM1 | 9124 | 208690_s_at | 0.2534 | 0.4802 | |
| GSE97050 | PDLIM1 | 9124 | A_23_P149992 | 0.9157 | 0.1998 | |
| SRP007169 | PDLIM1 | 9124 | RNAseq | 0.0962 | 0.8649 | |
| SRP008496 | PDLIM1 | 9124 | RNAseq | -0.0657 | 0.8464 | |
| SRP064894 | PDLIM1 | 9124 | RNAseq | 0.0266 | 0.9056 | |
| SRP133303 | PDLIM1 | 9124 | RNAseq | 0.2324 | 0.2468 | |
| SRP159526 | PDLIM1 | 9124 | RNAseq | -0.2020 | 0.7184 | |
| SRP193095 | PDLIM1 | 9124 | RNAseq | 0.2346 | 0.1554 | |
| SRP219564 | PDLIM1 | 9124 | RNAseq | 0.3094 | 0.3512 | |
| TCGA | PDLIM1 | 9124 | RNAseq | 0.1213 | 0.0499 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDLIM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDLIM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDLIM1 | 9124 | 1 | 8 | 21 | |
| GSE20123 | PDLIM1 | 9124 | 1 | 7 | 22 | |
| GSE43470 | PDLIM1 | 9124 | 0 | 7 | 36 | |
| GSE46452 | PDLIM1 | 9124 | 0 | 11 | 48 | |
| GSE47630 | PDLIM1 | 9124 | 2 | 14 | 24 | |
| GSE54993 | PDLIM1 | 9124 | 7 | 0 | 63 | |
| GSE54994 | PDLIM1 | 9124 | 2 | 10 | 41 | |
| GSE60625 | PDLIM1 | 9124 | 0 | 0 | 11 | |
| GSE74703 | PDLIM1 | 9124 | 0 | 5 | 31 | |
| GSE74704 | PDLIM1 | 9124 | 0 | 4 | 16 | |
| TCGA | PDLIM1 | 9124 | 6 | 26 | 64 |
Total number of gains: 19; Total number of losses: 92; Total Number of normals: 377.
Somatic mutations of PDLIM1:
Generating mutation plots.
Highly correlated genes for PDLIM1:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDLIM1 | ZBED5 | 0.788848 | 3 | 0 | 3 |
| PDLIM1 | SLCO3A1 | 0.783561 | 3 | 0 | 3 |
| PDLIM1 | GPHN | 0.775625 | 3 | 0 | 3 |
| PDLIM1 | RNF26 | 0.741912 | 3 | 0 | 3 |
| PDLIM1 | LGALS8 | 0.73832 | 3 | 0 | 3 |
| PDLIM1 | DLG5 | 0.727644 | 3 | 0 | 3 |
| PDLIM1 | SKA3 | 0.727143 | 3 | 0 | 3 |
| PDLIM1 | ATIC | 0.724726 | 3 | 0 | 3 |
| PDLIM1 | EIF5A | 0.711589 | 3 | 0 | 3 |
| PDLIM1 | SFT2D3 | 0.711292 | 3 | 0 | 3 |
| PDLIM1 | ABCB6 | 0.704727 | 3 | 0 | 3 |
| PDLIM1 | SBF2 | 0.70356 | 3 | 0 | 3 |
| PDLIM1 | PGAP2 | 0.697087 | 4 | 0 | 3 |
| PDLIM1 | TADA3 | 0.693496 | 4 | 0 | 3 |
| PDLIM1 | RNF40 | 0.690709 | 3 | 0 | 3 |
| PDLIM1 | TMEM170A | 0.689966 | 3 | 0 | 3 |
| PDLIM1 | TPM3 | 0.687901 | 3 | 0 | 3 |
| PDLIM1 | PIGL | 0.687571 | 3 | 0 | 3 |
| PDLIM1 | KLHL13 | 0.682286 | 4 | 0 | 3 |
| PDLIM1 | NARS2 | 0.680606 | 4 | 0 | 3 |
For details and further investigation, click here
